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5,285 Possible Causes for Decreased Platelet Count, Peripheral Neuropathy, Susceptibility to Hematologic Malignancies Increased

  • Gaucher Disease

    In addition to the classic manifestations, patients suffer from increased susceptibility to hematologic and nonhematologic malignancies.[ncbi.nlm.nih.gov] Comorbidities for peripheral neuropathy were excluded.[ncbi.nlm.nih.gov] Platelet Count [britannica.com] Serum Decreased Platelet Count [en.wikipedia.org] Serum Decreased Platelet Count Decreased platelet counts (thrombocytopenia) as well as low[symptoma.com]

  • Vitamin B12 Deficiency

    Vitamin B12 deficiency, which may present without anemia and as a peripheral neuropathy, is often misdiagnosed as diabetic neuropathy, although the clinical findings are usually[ncbi.nlm.nih.gov] Other laboratory findings associated with megaloblastic anemia include decreased white blood cell (WBC) count and platelet count.[labtestsonline.org] Participation included measuring vitamin B12 levels and assessing peripheral neuropathy using Neuropathy Total Symptom Score-6 (NTSS-6) questionnaire.[ncbi.nlm.nih.gov]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Chronic Alcoholism

    A consecutive sample of 62 chronic alcoholics was studied, 18 females and 44 males, aged between 28 and 69 years to assess the incidence and distribution of peripheral neuropathy[ncbi.nlm.nih.gov] FBC, clotting screen, renal testing and LFTs: Suspect excessive alcohol use if mean corpuscular volume (MCV) is raised and platelet count may be decreased or elevated liver[patient.info] The results show that alcohol-related neuropathy, especially when subclinical, seems to be frequent and mostly characterized by axonal degeneration of peripheral nerve fibres[ncbi.nlm.nih.gov]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Infectious Mononucleosis

    Neurologic complications are rare but may include encephalitis, seizures, Guillain-Barré syndrome, peripheral neuropathy, viral meningitis, myelitis, cranial nerve palsies[merck.com] , which is a decrease in platelets, the part of your blood that begins the clotting process inflammation of the heart complications that involve the nervous system, such as[healthline.com] A diagnosis of acute symmetrical sensorimotor peripheral neuropathy (Guillain-Barré syndrome) was made. The results of CSF cultures were negative.[dx.doi.org]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Pernicious Anemia

    Pernicious Anemia Macrocytic anemia, glossitis, peripheral neuropathy, weakness, hyperreflexia, ataxia, and other neurological manifestations characterize classical vitamin[clinlabnavigator.com] RBC and WBC counts are low. Platelet count is low. Red blood cell indices are usually normal.[labtestsonline.org] Cobalamin deficiency–related neurological impairment can vary in clinical presentation, including acute combined system degeneration, peripheral neuropathy, and psychosis.[emedicine.medscape.com]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Multiple Myeloma

    The mechanism of the development of the peripheral neuropathy is poorly understood.[ncbi.nlm.nih.gov] Decreases in blood cell counts. DARZALEX can decrease white blood cell counts which help fight infections and blood cells called platelets which help to clot blood.[darzalex.com] […] absolute neutrophil count, decreased phosphorus, anemia, neutropenia, decreased total white blood cell count, decreased platelets, diarrhea, fatigue, thrombocytopenia, pyrexia[investors.amgen.com]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Portal Cirrhosis

    Reduced levels of platelets or decreased white blood cell count. Cleveland Clinic News & More Cleveland Clinic News & More[my.clevelandclinic.org] When the spleen enlarges, the number (count) of white blood cells can decrease (increasing the risk of infections), and the number (count) of platelets can decrease (increasing[merckmanuals.com] […] anemia and thrombocytopenia ( low platelet count in the bloodstream).[medicinenet.com]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Sarcoidosis

    Peripheral neuropathy is a rare, yet treatable manifestation of sarcoidosis, a multisystem disorder characterized by the presence of non-caseating granulomas that are seldom[ncbi.nlm.nih.gov] Splenic enlargement is observed in 5–10%, it is usually minimal and asymptomatic and causes rarely decrease in the count of platelets, red and white cells [ 37 ].[dx.doi.org] Sarcoid neuropathy. In: Dyck PJ, Thomas PK, Lambert EH, Bunge R, editors. Peripheral neuropathy. 2nd ed. Phliadelphia: W. B. Saunders; 1984. p. 2018 –26.[dx.doi.org]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Leukemia

    Peripheral neuropathyPeripheral neuropathy, or numbness, tingling or pain in the hands and feet, can last months after therapy with agents such as Oncovin.[hopkinsmedicine.org] Decrease in blood cell counts. Decreased blood counts (white blood cells, platelets, and red blood cells) are common with IMBRUVICA , but can also be severe.[imbruvica.com] Testing for peripheral neuropathy before and while on levodopa is also very important. Patients should also be regularly monitored for dyskinesia.[ncbi.nlm.nih.gov]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Systemic Lupus Erythematosus

    neuropathy.[ncbi.nlm.nih.gov] […] blood cell count (leukopenia), decrease in lymphocytes (lymphopenia), or decrease in blood platelets ( thrombocytopenia ).[webmd.com] Inflammation of the lining around the lungs (pleuritis) or of the lining around the heart (pericarditis) Blood disorder , either low red blood cell count ( anemia ), low white[webmd.com]

    Missing: Susceptibility to Hematologic Malignancies Increased

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