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27 Possible Causes for Decreased Platelet Count, Pernicious Anemia not due to Intrinsic Factor Deficiency

  • Vitamin B12 Deficiency

    In pernicious anemia, the intrinsic factor necessary for vitamin B12 absorption is lacking, often due to an autoimmune factor.[livestrong.com] Other laboratory findings associated with megaloblastic anemia include decreased white blood cell (WBC) count and platelet count.[labtestsonline.org] […] term pernicious anemia is sometimes used colloquially to refer to any anemia caused by vitamin B12 deficiency.[uofmhealth.org]

  • Pernicious Anemia

    Technically, the term "pernicious anemia" refers to vitamin B12 deficiency due to a lack of intrinsic factor.[web.archive.org] RBC and WBC counts are low. Platelet count is low. Red blood cell indices are usually normal.[labtestsonline.org] The differential white blood count shows a decrease in most types of cells but not lymphocytes .[labtestsonline.org]

  • Iron Deficiency Anemia

    A vitamin B12 deficiency due to pernicious anemia (positive intrinsic factor antibodies) was also highlighted, but this was not enough to explain the anemia without macrocytosis[ncbi.nlm.nih.gov] The biological assessment initially showed a profound microcytic, aregenerative, iron deficiency anemia.[ncbi.nlm.nih.gov]

  • Folate-Deficiency Anemia

    Megaloblastic anemia due to vitamin B12 deficiency caused by a lack of intrinsic factor is specifically referred to as pernicious anemia.[med-ed.virginia.edu] Significant blood test findings include macrocytosis, decreased reticulocyte count, abnormal platelets, and a serum folate less than 4 mg/ml.[innvista.com] Megaloblastic anemia is most often due to a B12 or folate deficiency, but the cause of the deficiency must be determined for proper treatment.[med-ed.virginia.edu]

  • Thrombotic Thrombocytopenic Purpura

    Severe vitamin B 12 deficiency is most often caused by a loss of intrinsic factor due to autoimmune gastritis (“pernicious anemia”), 2 as was the case with our patient.[consultant360.com] In one case, after an initial response to plasma exchange, a decrease in platelet count was observed on Day 7.[ncbi.nlm.nih.gov] […] to achieve a platelet count response.[doi.org]

  • Anemia due to Vitamin B6 Deficiency

    Pernicious anemia definition and facts Pernicious anemia is defined as a type of vitamin B12 deficiency that results from impaired uptake of vitamin B-12 due to the lack of[medicinenet.com] Platelet Count Platelets are fragments of cells that participate in clotting. They initiate repair of blood vessel walls.[drkaslow.com] […] a substance known as intrinsic factor (IF) produced by the stomach lining.[medicinenet.com]

  • Congenital Intrinsic Factor Deficiency

    anemia - Gastric intrinsic factor deficiency - Hereditary juvenile meganoblastic anemia due to intrinsic factor deficiency - IFD - Intrinsic factor deficiency Classification[csbg.cnb.csic.es] Vit.B12 is given parenterally at a dose of 1mg- followup shows decrease in MCV,reticulocytosis and improvement in platelet and neutrophil counts.[slideshare.net] pernicious anemia Congenital deficiency of intrinsic factor Megaloblastic anemia due to congenital deficiency of intrinsic factor Megaloblastic anemia due to inborn errors[healthprovidersdata.com]

  • Anemia

    Pernicious anemia is caused by a lack of intrinsic factor, which is required to absorb vitamin B12 from food.[en.wikipedia.org] Some decrease in factors V and VII is noted in comparison with whole blood. Each unit of platelets raises the platelet count by approximately 10,000/µL.[emedicine.com] A blood sample will provide an overall count of your white blood cells , red blood cells and platelets .[radiologyinfo.org]

  • Constitutional Anemia due to Iron Metabolism Disorder

    […] to intrinsic factor deficiency ; Anemia, pernicious; Pernicious anemia ; Addison anemia ; Biermer anemia ; Pernicious (congenital) anemia ; Congenital intrinsic factor deficiency[icd10data.com] H and H Decreased MCV, MCH and MCHC increased RDW developing condition Decreased (variable) retic count production problem increased platelets variable wbc count smear: microcytes[quizlet.com] anemia 2016 2017 2018 2019 Billable/Specific Code Applicable To Vegan anemia Vitamin B12 deficiency anemia due to intrinsic factor deficiency Vitamin B12 defic anemia due[icd10data.com]

  • Megaloblastic Anemia

    Megaloblastic anemia that arises due to lack of intrinsic factor is called pernicious anemia.[medindia.net] The platelet count may be reduced. Neutrophil granulocytes may show multisegmented nuclei ("senile neutrophil").[en.wikipedia.org] Megaloblastic anemia that arises due to lack of intrinsic factor is called pernicious anemia .[medindia.net]

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