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1,227 Possible Causes for Decreased Platelet Count, Progressive or Intermittent Jaundice, Reticulocytes Increased

  • Hereditary Spherocytosis

    Reticulocyte count: Increased Treatment: Splenectomy is indicated for moderate to severe cases, but not mild cases.[medical-labs.net] Postoperative markedly elevated platelet count was maintained up to 6 months, and after that, platelet count gradually decreased to normal values.[ncbi.nlm.nih.gov] At the age of 10 months after confirming stability of platelet counts, tapering betamethasone resulted in gradually decreasing hemoglobin levels and platelet counts (hemoglobin[jhoonline.biomedcentral.com]

    Missing: Progressive or Intermittent Jaundice
  • HELLP Syndrome

    […] risk in preeclampsia Counts of 3 meet HELLP criterion Blood smear – evaluate for evidence of microangiopathic hemolysis Helmet cells Burr cells Schistocytes Reticulocyte[arupconsult.com] Despite considerable patient variation, most gravid women with HELLP syndrome had decreasing platelet counts until 24 to 48 hours after delivery.[ncbi.nlm.nih.gov] Postoperatively, the platelet count and antithrombin III level decreased, and computed tomography revealed intramuscular hematomas that possibly were related to vascular injury[ncbi.nlm.nih.gov]

    Missing: Progressive or Intermittent Jaundice
  • Primary Myelofibrosis

    The percentage of reticulocytes is mildly increased but may vary widely in a given case.[patient-help.com] Platelet counts initially may be high, normal, or decreased; however, thrombocytopenia tends to supervene as the disorder progresses.[merck.com] Side effects may include worsening anaemia or a low platelet count. Ruxolitinib is the only JAK2 inhibitor currently licenced for use in Australia.[leukaemia.org.au]

    Missing: Progressive or Intermittent Jaundice
  • Paroxysmal Nocturnal Hemoglobinuria

    Erythrocytes fractionated by centrifugation revealed increased glycolytic enzyme activities of hexokinase, G3PD, PGK, TPI, PK, LDH, G6PD, and 6PGD in the reticulocyte-rich[pediatrics.aappublications.org] If the PNH occurs in the setting of known (or suspected) aplastic anemia, abnormal white blood cell counts and decreased platelet counts may be seen at this.[en.wikipedia.org] Blockade of terminal complement components presumably prolongs the survival of type III erythrocytes (since there was no simultaneous increase in reticulocytes), which are[nejm.org]

    Missing: Progressive or Intermittent Jaundice
  • Autoimmune Hemolytic Anemia

    Over the course of the next 5 days, the Hb and Hct decreased to 4.1 g/dL and 12%, respectively, direct bili increased to 12.3 mg/day, reticulocytes slightly increased to 0.9%[ncbi.nlm.nih.gov] Median absolute reticulocyte counts decreased from 236 to 109 x 10(9)/L (P .01).[ncbi.nlm.nih.gov] Laboratory data showed low hemoglobin levels and slightly increased reticulocyte counts, while direct and indirect antiglobulin tests were positive.[ncbi.nlm.nih.gov]

    Missing: Progressive or Intermittent Jaundice
  • Bone Metastasis

    Bone metastases, or osseous metastatic disease, is a category of cancer metastases that results from primary tumor invasion to bone. Bone-originating primary tumors such as osteosarcoma, chondrosarcoma, and Ewing's sarcoma are rare. Unlike hematological malignancies that originate in the blood and form non-solid[…][en.wikipedia.org]

    Missing: Progressive or Intermittent Jaundice
  • Sickle Cell Disease

    With each course, fetal reticulocytes increased within 48-72 h, peaked in 7-11 d, and fell by 18-21 d.[doi.org] count, platelet count and reticulocyte count (p   0.00, p   0.03, p   0.02, respectively).[ncbi.nlm.nih.gov] On her third day of admission, due to hemoglobin (Hb) value of 6.9 g/dL with increase in reticulocytes, the patient was transfused with one unit of compatible leukodepleted[ncbi.nlm.nih.gov]

    Missing: Progressive or Intermittent Jaundice
  • Viral Hepatitis

    Viral hepatitis is liver inflammation due to a viral infection. It may present in acute form as a recent infection with relatively rapid onset, or in chronic form. The most common causes of viral hepatitis are the five unrelated hepatotropic viruses hepatitis A, B, C, D, and E. Other viruses can also cause liver[…][en.wikipedia.org]

    Missing: Progressive or Intermittent Jaundice
  • Hemolytic Uremic Syndrome

    reticulocytes reduced haptoglobins increased LDH unconjugated hyperbilirubinaemia with urinary urobilinogen variable neutrophilia increased urea and creatinine levels (greater[lifeinthefastlane.com] This results in platelet activation endothelial cell damage, and white blood cell activation, leading to systemic TMA, which manifests as decreased platelet count, hemolysis[en.wikipedia.org] L-lactate dehydrogenase level Leukocytosis Negative Coombs’ test Proteinuria on urinalysis Reticulocyte count moderately elevated Stool culture positive for Shiga toxin–roducing[aafp.org]

    Missing: Progressive or Intermittent Jaundice
  • Gaucher Disease

    Platelet Count [britannica.com] Serum Decreased Platelet Count [en.wikipedia.org] Serum Decreased Platelet Count Decreased platelet counts (thrombocytopenia) as well as low[symptoma.com] Decreased platelet counts (thrombocytopenia) as well as low hemoglobin (anemia) and decreased white blood cell counts (leukopenia) result in easy bruisability and hence black-and-blue[scientificamerican.com] […] blood cell count causing anemia Individuals with anemia may have fatigue, low energy, and decreased exercise tolerance Decreased platelet count can cause easy bruising Bone[dovemed.com]

    Missing: Progressive or Intermittent Jaundice

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