Create issue ticket

1,618 Possible Causes for Decreased Platelet Count, Susceptibility to Hematologic Malignancies Increased, Swollen Knee

  • Gaucher Disease

    In addition to the classic manifestations, patients suffer from increased susceptibility to hematologic and nonhematologic malignancies.[ncbi.nlm.nih.gov] Platelet Count [britannica.com] Serum Decreased Platelet Count [en.wikipedia.org] Serum Decreased Platelet Count Decreased platelet counts (thrombocytopenia) as well as low[symptoma.com] Decreased platelet counts (thrombocytopenia) as well as low hemoglobin (anemia) and decreased white blood cell counts (leukopenia) result in easy bruisability and hence black-and-blue[scientificamerican.com]

  • Common Variable Immunodeficiency

    On admission he presented with three tender and swollen joints (right knee, shoulder, ankle), moderately elevated C-reactive protein (CRP) levels (5 to 29 mg/dl) and severe[arthritis-research.biomedcentral.com] […] to infections, autoimmune diseases, hematologic malignancy, or death caused by infection in other family members should increase the provider’s index of suspicion for CVID[mdedge.com] […] malignant diseases. 15 Although the majority of CVID cases occur sporadically, family history is helpful in securing the correct diagnosis. 15 Known immunodeficiency, unusual susceptibility[mdedge.com]

  • Fracture

    Ann Anat. 2018 Mar;216:120-124. doi: 10.1016/j.aanat.2017.12.005. Epub 2018 Jan 1. Author information 1 Studio Fonzar, Strada dei Tigli, 54, 33030 Campoformido, UD, Italy. Electronic address: federica.fonzar@gmail.com. 2 Department of Stomatology, Universitat de València (Spain) Clínica Odontológica, Calle Gascó Oliag, 1, 46010[…][ncbi.nlm.nih.gov]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Henoch-Schönlein Purpura

    , ankles) - swollen, painful joints; may cause difficulty in weight-bearing Gastrointestinal tract Abdominal pain is common, and is generally intermittent and colicky in nature[pch.health.wa.gov.au] When accompanied by a decrease in the circulating platelets, it is called thrombocytopenic purpura ; when there is no decrease in the platelet count, it is called nonthrombocytopenic[medical-dictionary.thefreedictionary.com] […] joints can occur due to inflammation, usually affecting the knees and ankles Kidneys Protein and blood may be found in the urine due to inflammation in the kidneys.[gosh.nhs.uk]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Hemophilia

    Often there is no pain at first, but if it continues, the joint may become hot to the touch, swollen, and painful to move.[my.clevelandclinic.org] The occurrence of joint bleeds increases as a baby begins to walk; these episodes can vary in severity, from swelling with mild pain to extremely swollen with severe pain.[physio-pedia.com] People with hemophilia may have any type of internal bleeding, but most often it is in the muscles and joints, such as the elbows, knees, hips, shoulders, and ankles.[my.clevelandclinic.org]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Multiple Myeloma

    Decreases in blood cell counts. DARZALEX can decrease white blood cell counts which help fight infections and blood cells called platelets which help to clot blood.[darzalex.com] […] absolute neutrophil count, decreased phosphorus, anemia, neutropenia, decreased total white blood cell count, decreased platelets, diarrhea, fatigue, thrombocytopenia, pyrexia[investors.amgen.com] Patients may also have: Anemia (low red blood cell count) Leukopenia (low white blood cell count) Thrombocytopenia (low platelet count) Hypercalcemia (high calcium level in[orthoinfo.aaos.org]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Systemic Lupus Erythematosus

    […] blood cell count (leukopenia), decrease in lymphocytes (lymphopenia), or decrease in blood platelets ( thrombocytopenia ).[webmd.com] (CBC) – may reveal anemia and decreased numbers of white blood cells and platelets, which can occur with lupus Comprehensive metabolic panel (CMP) – indicates current status[labtestsonline.org] Inflammation of the lining around the lungs (pleuritis) or of the lining around the heart (pericarditis) Blood disorder, either low red blood cell count ( anemia ), low white[webmd.com]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Felty's Syndrome

    A flare-up of arthritis and a decrease in platelet counts were observed.[ncbi.nlm.nih.gov] A flare-up of arthritis and a decrease in platelet counts were observed. 1994 S.[karger.com] Viruses Chickenpox, mumps, rubella, Epstein-Barr virus, or parvovirus can decrease your platelet count for a while. People who have AIDS often develop thrombocytopenia.[nhlbi.nih.gov]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Serum Sickness

    Serum sickness is a type III hypersensitivity reaction mediated by immune complex deposition with subsequent complement activation, small-vessel vasculitis, and tissue inflammation. Although the overall incidence of serum sickness is declining because of decreased use of heterologous sera and improved vaccinations, rare[…][ncbi.nlm.nih.gov]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Portal Cirrhosis

    […] disease progresses, the following symptoms may occur: itchy skin, dry eyes and mouth, fatigue, high cholesterol, greasy diarrhea, hypothyroidism, osteoporosis, ascites, swollen[marylandhearingcenter.com] Reduced levels of platelets or decreased white blood cell count. Cleveland Clinic News & More Cleveland Clinic News & More[my.clevelandclinic.org] When the spleen enlarges, the number (count) of white blood cells can decrease (increasing the risk of infections), and the number (count) of platelets can decrease (increasing[merckmanuals.com]

    Missing: Susceptibility to Hematologic Malignancies Increased