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62 Possible Causes for Decreased Platelet Count, T-Lymphocyte Count Increased

  • Infectious Mononucleosis

    , which is a decrease in platelets, the part of your blood that begins the clotting process inflammation of the heart complications that involve the nervous system, such as[healthline.com] […] protein in red blood cells Thrombocytopenia — a low count of platelets, which are blood cells involved in clotting Heart problems — an inflammation of the heart muscle (myocarditis[mayoclinic.com] Rare complications According to the Mayo Clinic, mono can also cause some of these extremely rare complications: anemia, which is a decrease in your red blood cell count thrombocytopenia[healthline.com]

  • Primary Immune Deficiency Disorder

    Skin infections become more common as the number of CD4 T- lymphocytes reduces. Mild reduction in CD4 T- lymphocyte count ( 200) is part of normal ageing.[dermnetnz.org] Moderate reduction in CD4 T- lymphocyte count (200-50) occurs in some elderly patients, newborn babies, and in primary immunodeficiency diseases.[dermnetnz.org] This leads to an increased incidence of herpes zoster (shingles) and in countries where it is prevalent, old-world or classic Kaposi sarcoma.[dermnetnz.org]

  • Multiple Myeloma

    Decreases in blood cell counts. DARZALEX can decrease white blood cell counts which help fight infections and blood cells called platelets which help to clot blood.[darzalex.com] […] absolute neutrophil count, decreased phosphorus, anemia, neutropenia, decreased total white blood cell count, decreased platelets, diarrhea, fatigue, thrombocytopenia, pyrexia[investors.amgen.com] Patients may also have: Anemia (low red blood cell count) Leukopenia (low white blood cell count) Thrombocytopenia (low platelet count) Hypercalcemia (high calcium level in[orthoinfo.aaos.org]

  • Acute Lymphoblastic Leukemia

    The increase in the ALC was primarily from activated CTL019 T lymphocytes. Patient 1 was a 7-year-old girl with a second recurrence of ALL.[doi.org] After 16 months, the results of routine blood tests showed reduced hemoglobin levels and decreased platelet counts.[ncbi.nlm.nih.gov] The bleeding in ALL is due to decreased platelet counts and occurs in the skin and mucosal surfaces, manifesting as purpura and ecchymosis .[lecturio.com]

  • Wiskott Aldrich Syndrome

    Diagnosis Presentation: Children 1-2 years present with easy bruising, bleeding tendencies, decreased platelet counts. Bacterial infection is also seen.[rarediseasesindia.org] Eltrombopag treatment resulted in an increased platelet count in 5 out of 8 patients.[ncbi.nlm.nih.gov] Immunoglobulin levels Platelet count and volume assessment WBC function tests (eg, neutrophil chemotaxis, T-cell function) Diagnosis of Wiskott-Aldrich syndrome is based on[msdmanuals.com]

  • Influenza

    Deterioration of CD4 T-lymphocyte cell counts or progression of HIV disease has not been demonstrated among HIV-infected persons after influenza vaccination compared with[cdc.gov] […] leukocyte, platelet, and particularly, lymphocyte counts at the time of admission.[doi.org] Deterioration of CD4 T-lymphocyte cell counts or progression of HIV disease have not been demonstrated among HIV-infected persons after influenza vaccination compared with[cdc.gov]

  • Hepatitis

    Biomarkers In the case of NASH, the number of serum platelets decreases as the fibrosis advances. In the case of HCV infection, platelet counts also decrease.[doi.org] It has been suggested that patients should initially receive 1 unit per 10 kg body weight and the effect of this transfusion be assessed by the platelet count obtained one[web.archive.org] […] hour later. 58 However, post-transfusion platelet increments do not necessarily correlate with decreased risk of bleeding as platelet function may vary and it has been shown[web.archive.org]

  • Aplastic Anemia

    CD3 T-lymphocyte ratios decreased only in the KQ group, while CD3 CD4 CD8 Tlymphocytes increased only in the KC group after 6 months (P 0.05).[ncbi.nlm.nih.gov] After 11 cycles of PEM maintenance therapy, the patient's platelet count decreased, and progressed to pancytopenia within two months.[ncbi.nlm.nih.gov] Transfusions are given when red cell counts decrease, patients with adequate platelet counts who have blood clots may receive blood thinners, and low white cell and platelet[marrowforums.org]

  • Exchange Transfusion

    The values of hemoglobin and hematocrite were reduced, red blood cell count was similar, while the white blood cell particularly the monocyte count was increased compared[ncbi.nlm.nih.gov] […] the mean platelet count fell significantly, after simple transfusion in the ST RCE group.[ncbi.nlm.nih.gov] counts decrease to Because many of the complications of exchange transfusion are probably unavoidable, the best way to reduce complications is to prevent the need for exchange[pediatrics.aappublications.org]

  • Autoimmune Thrombocytopenia

    Analysis of lymphocyte subsets revealed an increased number of CD3 gamma/delta T cells.[ncbi.nlm.nih.gov] Although platelet counts gradually decreased within a few days post-transfusion, bleeding was stopped in all cases.[ncbi.nlm.nih.gov] However, the patient's platelet count decreased to 9 x 10(9) cells/L on day 222. The platelet-associated immunoglobulin G (PAIgG) values were elevated.[ncbi.nlm.nih.gov]

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