Create issue ticket

46 Possible Causes for Decreased Platelet Count, Virus Associated Hemophagocytic Syndrome

  • Sickle Cell Disease

    count, platelet count and reticulocyte count (p   0.00, p   0.03, p   0.02, respectively).[ncbi.nlm.nih.gov] Hydroxyurea increases the concentration of fetal Hb (Hb F), decreases the leukocyte count, decreases the platelet count, and improves blood rheology.[clinicaladvisor.com] Benefits include increasing haemoglobin concentrations, and decreasing platelet and white cell counts. [ 1 ] Concerns remain about its myelosuppressive and teratogenic effects[patient.info]

  • Malignant Histiocytosis

    The differential diagnosis among hemophagocytic syndromes and particularly between the virus-associated hemophagocytic syndrome (VAHS) and the malignant histiocytosis (HM)[ncbi.nlm.nih.gov] @article{bcdd39714f824a70a344d180d388782a, title "Hyperferritinemia in malignant histiocytosis and virus-associated hemophagocytic syndrome", abstract "There are few clinical[jhu.pure.elsevier.com] Abstract Data on 28 patients with malignant histiocytosis (MH), fourteen patients with virus-associated hemophagocytic syndrome (VAHS) and two patients with familial erythrophagocytic[ncbi.nlm.nih.gov]

  • Infectious Mononucleosis

    Severe chronic active Epstein-Barr virus infection accompanied by virus-associated hemophagocytic syndrome, cerebellar ataxia and encephalitis.[emedicine.medscape.com] , which is a decrease in platelets, the part of your blood that begins the clotting process inflammation of the heart complications that involve the nervous system, such as[healthline.com] […] protein in red blood cells Thrombocytopenia — a low count of platelets, which are blood cells involved in clotting Heart problems — an inflammation of the heart muscle (myocarditis[mayoclinic.com]

  • Chronic Active Hepatitis B

    Bone marrow biopsy showed hypocellularity, histiocytic hyperplasia, and hemophagocytosis consistent with a virus-associated hemophagocytic syndrome (VAHS).[ncbi.nlm.nih.gov] To our knowledge this is the first report of a hemophagocytic syndrome in that setting.[ncbi.nlm.nih.gov] The condition was interpreted as VAHS associated with chronic active hepatitis B and acute hepatitis C virus infection.[ncbi.nlm.nih.gov]

  • Pancytopenia

    Virus-associated hemophagocytic syndrome and hemorrhagic jejunal ulcer caused by cytomegalovirus infection in a noncompromised host; a case report of unusual entity.[scielo.br] counts.[njlm.net] Craig F, Clare N, Sklar J, Banks P (1991) T-cell lymphoma and the virus-associated hemophagocytic syndrome. Am J Clin Pathol 97: 189–194. View Article Google Scholar 16.[journals.plos.org]

  • Drug Hypersensitivity

    […] of Epstein-Barr Virus and/or Cytomegalovirus Leading to Hemophagocytic Syndrome in One of Two Patients, Annals of Dermatology, 30, 1, (71), (2018).[doi.org] Jianhua Liang, Hui Qu, Xiaowen Wang, Aiping Wang, Lingling Liu, Ping Tu, Ruoyu Li and Mingyue Wang, Drug Reaction with Eosinophilia and Systemic Symptoms Associated with Reactivation[doi.org]

  • Castleman Disease

    […] lymphoma; HLH-MAS, hemophagocytic lymphohistiocytosis- macrophage activation syndrome; IgG4, IgG4-related disease; JIA, juvenile idiopathic arthritis; M-HLH, malignancy-associated[doi.org] The observed side effects were low platelet counts and low fibrin levels, with no macrophage activation syndrome ( Fig. 1 ) and an episode of herpes zoster.[mct.aacrjournals.org] count (thrombocytopenia) Elevated lymphocytes and plasma cells (polyclonal lymphocytosis and plasmacytosis) Elevated BUN and creatinine (decreased kidney function) Proteinuria[cdcn.org]

  • Precursor-Cell Lymphoblastic Leukemia

    Late-onset fatal Epstein-Barr virusassociated hemophagocytic syndrome following cord blood cell transplantation for adult acute lymphoblastic leukemia .[ajcp.oxfordjournals.org] After 16 months, the results of routine blood tests showed reduced hemoglobin levels and decreased platelet counts.[ncbi.nlm.nih.gov] The bleeding in ALL is due to decreased platelet counts and occurs in the skin and mucosal surfaces, manifesting as purpura and ecchymosis .[lecturio.com]

  • Hodgkin Lymphoma

    Hodgkin lymphoma-associated hemophagocytic syndrome: a disorder strongly correlated with Epstein-Barr virus. Clin Infect Dis. 2008 Aug 15. 47(4):531-4. [Medline].[emedicine.medscape.com]

  • Severe Aplastic Anemia

    In virus-associated hemophagocytic syndrome with an acute parvovirus B19 infection, raised levels of cytokines such as interferon γ would impair regulation of the phagocytic[omicsonline.org] Transfusions are given when red cell counts decrease, patients with adequate platelet counts who have blood clots may receive blood thinners, and low white cell and platelet[marrowforums.org] RBC and WBC counts are low. Platelet count is low. Red blood cell indices are usually normal.[labtestsonline.org]

Further symptoms