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218 Possible Causes for Decreased Proprioception, Peripheral Neuropathy

  • Friedreich Ataxia

    There is progressive ataxia, dysarthria, decreased proprioception/vibration sense and muscle weakness. The inheritance is autosomal recessive.[] neuropathy resembling Friedreich’s ataxia, and markedly reduced plasma levels of vitamin E.[] It is frequently associated with cardiomyopathy or diabetes. [ 1 ] There is progressive ataxia, dysarthria, decreased proprioception/vibration sense and muscle weakness.[]

  • Diabetic Peripheral Neuropathy

    Individuals who develop DPN often experience severe, uncontrolled pain in the lower extremities, insensate feet, and decreased proprioceptive skills.[] Peripheral neuropathy is the most common complication of diabetes.[] It causes decreased sensation, proprioception, reflexes, and strength in the lower extremities, leading to balance dysfunction.[]

  • Subacute Combined Degeneration of Spinal Cord

    The patient neurological examination shows a reduced power and decreased proprioception and vibration sense of hands due to vitamin...[] Neuropathological examination in such cases reveals loss of dorsal ganglionic neurons with degeneration of their peripheral and central axons (peripheral neuropathy and posterior[] Peripheral neuropathy: Vitamin deficiency can also be associated with peripheral neuropathy, so a variety of vitamin deficiency at the same time there are B12 deficiency in[]

  • Spinal Cord Compression

    […] lower extremity sensation, and decreased proprioception.[] The symptoms of cervical myelopathy can be similar to the symptoms of peripheral neuropathy, cubital tunnel syndrome, or carpal tunnel syndrome.[] It is important to get a complete examination and for a qualified health care professional to differentiate a peripheral neuropathy, cauda equina syndrome, and cervical myelopathy[]

  • Vitamin E Deficiency

    For example, protect the hands and feet from injury due to decreased vibratory sense and proprioception. Assist with energy-conservation techniques.[] A 24-year-old male, who suffered since childhood from a progressive form of ataxia associated with peripheral neuropathy, was found severely deficient in serum vitamin E.[] Absence of neuropathy or mild peripheral neuropathy was noted in more than half of the cohort.[]

  • Wernicke Encephalopathy

    proprioception.[] Wernicke’s Encephalopathy A clinical tetrad of: Acute confusional state ophthalmoplegia- commonly CN VI palsy nystagmus ataxic gait with associated features including: peripheral[] .  Gait ataxia – cerebellar damage, and vestibular paresis  Peripheral neuropathy – foot drop, and decreased proprioception 9.[]

  • Pernicious Anemia

    Cobalamin deficiency–related neurological impairment can vary in clinical presentation, including acute combined system degeneration, peripheral neuropathy, and psychosis.[] Pernicious Anemia Macrocytic anemia, glossitis, peripheral neuropathy, weakness, hyperreflexia, ataxia, and other neurological manifestations characterize classical vitamin[] neuropathy Progressive lesions on the spinal cord Memory loss Pernicious anemia diagnosis There are many tests that a doctor can perform in order to properly diagnose pernicious[]

  • Spinocerebellar Ataxia Type 1

    […] muscle tone Low muscle tone [ more ] 0001290 Hyperactive deep tendon reflexes 0006801 Hypermetric saccades 0007338 Hyporeflexia Decreased reflex response Decreased reflexes[] In SCA2, earlier onset and more severe ataxia were associated with peripheral neuropathy.[] These data confirm that SCA1 phenotype is characterised by early and prevalent pyramidal tract involvement and that peripheral neuropathy is a late and moderate complication[]

  • Multiple Sclerosis

    Peripheral neuropathy and diffuse white matter (WM) changes on brain MRI were also observed. Both patients had a preliminary diagnosis of primary progressive MS.[] If patient develops symptoms consistent with peripheral neuropathy, evaluate patient and consider discontinuing.[]

  • Hereditary Spastic Paraplegia

    Orthostatic intolerance, urinary symptoms, hyperreflexia in the biceps and knee jerk, and decreased proprioception in both limbs were observed on neurological examinations[] This study adds to the evidence associating the known occurrence of mild peripheral neuropathy in the adult onset SPG10 type of AD-HSP.[] Most patients with an SPG3A mutation present with a pure phenotype and early-onset disease, although complicated forms with peripheral neuropathy are also reported.[]

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