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111 Possible Causes for Deep Plantar Crease

  • Costello Syndrome

    Both patients had manifestations of Costello syndrome with thick, lax skin on the dorsal aspects of hands and feet, deep palmar and plantar creases, curly hair, hyperkeratoses[ncbi.nlm.nih.gov] We describe a 34-year-old woman with mental retardation, short stature, macrocephaly, a "coarse" face, hoarse voice, and redundant skin with deep palmar and plantar creases[ncbi.nlm.nih.gov] Costello syndrome is a rare, distinctive, multiple congenital anomaly syndrome, characterized by soft, loose skin with deep palmar and plantar creases, loose joints, distinctive[ncbi.nlm.nih.gov]

  • Waters-West Syndrome

    plantar creases Abdomen Spleen: hepatosplenomegaly Skeletal Feet: increased space between first and second toes Clinical features from OMIM: 600461 Genetic tests related[malacards.org] plantar creases, and increased space between the first and second toes.[orpha.net] plantar creases 33 HP:0001869 25 abnormal external genitalia 33 HP:0000811 26 hepatosplenomegaly 33 HP:0001433 Symptoms via clinical synopsis from OMIM: 58 Abdomen External[malacards.org]

  • Mowat-Wilson Syndrome

    plantar creases Deep wrinkles in soles of feet 0001869 Ectopic kidney Abnormal kidney location Displaced kidney [ more ] 0000086 Finger syndactyly 0006101 Hallux valgus Bunion[rarediseases.info.nih.gov] […] in size of the outer layer of the brain due to loss of brain cells 0002120 Cleft palate Cleft roof of mouth 0000175 Cleft upper lip Harelip 0000204 Constipation 0002019 Deep[rarediseases.info.nih.gov]

  • Talipes Cavus

    Clinically, complex clubfoot is characterized as short, stubby foot, having rigid equinus, severe adduction and plantar flexion of all metatarsals, a deep crease above the[vestnik.szd.si]

  • Hypertrichotic Osteochondrodysplasia

    plantar creases Deep wrinkles in soles of feet 0001869 Delayed skeletal maturation Delayed bone maturation Delayed skeletal development [ more ] 0002750 Epicanthus Eye folds[rarediseases.info.nih.gov] She also had unusual, deep plantar creases, not previously reported in Cantu syndrome. Robertson et al. (1999) reviewed reported cases of Cantu syndrome.[genome.jp] plantar creases Ovoid vertebral bodies Broad hallux phalanx Short hallux Abnormal heart valve morphology Thin ribs Elevated alkaline phosphatase Bicuspid aortic valve Low[mendelian.co]

  • Foot Deformity

    […] surface, and a deep crease on the lateral dorsal side of the foot.[aafp.org] […] might be present in up to 60 percent of children with congenital vertical talus. 10, 13 The foot examination usually reveals a rigid foot with a “reversed” arch, a convex plantar[aafp.org]

  • Cardiomegaly

    She also had unusual, deep plantar creases, not reported previously in Cantú syndrome.[ncbi.nlm.nih.gov]

  • Kleiner Holmes Syndrome

    plantar creases Deep plantar creases HP:0001869 - 26.1.4 Abnormal dermatoglyphics on feet - - - 26.1.5 Absent feet - - - 26.1.6 Asymmetric feet - - - 26.1.7 Split/cleft foot[compbio.charite.de] Term HPO ID Comment 26.1.0 Feet, general abnormalities - - - 26.1.1 Flat arches of feet - - - 26.1.2 High arches of feet (pes cavus) Pes cavus HP:0001761 - 26.1.3 Abnormal/deep[compbio.charite.de]

  • Kohlschütter-Tönz Syndrome

    Excessive wrinkled skin Deep plantar creases Intention tremor Cortical visual impairment Generalized joint laxity Truncal ataxia Abnormality of vision Palmoplantar cutis[mendelian.co] […] palmar crease Nail dysplasia Trigonocephaly Dental malocclusion Hypoplasia of the musculature Short nail Knee flexion contracture Venous thrombosis Decreased liver function[mendelian.co] […] laxa Telangiectasia Hemangioma Prominent nasolabial fold Reduced protein S activity Fragile nails Abnormal macular morphology Deep venous thrombosis Type I transferrin isoform[mendelian.co]

  • Mosaic Trisomy 1

    Figure 1: Dysmorphic features and deep palmo-plantar creases.[omicsonline.org] […] palmar and plantar creases ( Figures 1a-1c ).[omicsonline.org] […] palmar-plantar creases, and cardiac-renal abnormalities.[omicsonline.org]

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