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73 Possible Causes for Deep White Matter Changes, Dementia, Generalized Motor Seizure

  • Binswanger Disease

    OBJECTIVES: To analyse the diagnostic and prognostic value of periventricular hyperintensity (PVH) and deep white matter hyperintensity (DWMH) magnetic resonance imaging ([ncbi.nlm.nih.gov] Clinically, Lacunar Dementia presents with gait difficulties, urinary incontinence, parkinsonian features, pseudobulbar palsy, emotional incontinence and dementia.[ncbi.nlm.nih.gov] The GFAP and MT-I-II expressions in subsets of reactive astrocytes in the cortico-subcortical layers together with regressive astroglial changes in the deep white matter suggest[content.iospress.com]

  • Stroke

    Early features include: loss of grey-white matter differentiation, and hypoattenuation of deep nuclei: lentiform nucleus changes seen as early as 1 hour after occlusion, visible[radiopaedia.org] Stroke is a strong, independent, and potentially modifiable risk factor for all-cause dementia.[ncbi.nlm.nih.gov] We increase understanding of the causes of cerebrovascular disease and improve the prevention of stroke and vascular dementia in routine clinical practice.[ndcn.ox.ac.uk]

  • Metabolic Encephalopathy

    ; and seizures.[ncbi.nlm.nih.gov] white matter changes may be seen, with the appearance of hyperintensity on T2 sequences in the region of internal capsule, corona radiata, and splenium of corpus callosum[neurologyindia.com] The neurological disease complex associated with virus infection occurs in a large proportion of infected patients and is commonly referred to as HIV-1 associated dementia[ncbi.nlm.nih.gov]

  • Dementia

    It may be particularly related to frontal deep white matter lesions. 16 Cognitive and behavioral changes in SVD are due to disruption of the frontal cortico-subcortical circuit[doi.org] […] as a public health priority; increasing awareness of dementia and establishing dementia-friendly initiatives; reducing the risk of dementia; diagnosis, treatment and care[who.int] Memory loss is a common symptom of dementia. However, memory loss by itself does not mean you have dementia.[web.archive.org]

  • Diffuse Cerebral Sclerosis of Schilder

    change in the deep white matter.[doi.org] The clinical course tends to be progressive and includes dementia, cortical blindness, cortical deafness, spastic hemiplegia, and pseudobulbar palsy.[icd9data.com] Signs and symptoms include dementia, cortical deafness and blindness, pseudobulbar palsy, and hemiplegia. (NCI Thesaurus) ALSO IN ENCYCLOPEDIA :[tititudorancea.com]

  • Creutzfeldt Jakob Disease

    Creutzfeldt Jakob disease is characterized by dementia, motor dysfunction, twitches, seizures, psychosis, and hallucinations.The duration of the disease is generally less[symptoma.com] Some other features, such as the presence of abnormal hyperintensity in the periaqueductal gray matter and posterior deep white matter tracts, were also common, and although[ajnr.org] Abstract Creutzfeldt-Jakob disease (CJD) is a rare prion disease that leads to a rapidly progressive dementia (RPD) and associated neurological features.[ncbi.nlm.nih.gov]

  • Herpes Simplex Encephalitis

    In children, the most common type of HSV is type 1, and generally affects the frontotemporal lobes of the brain affecting cognition and motor function.[encephalitis.info] The frontal dysexecutive syndrome and personality change could be explained by the involvement of frontal lobe white matter and the sensory symptoms, diplopia, and increased[jamanetwork.com] Abstract A very challenging problem in the domain of the cognitive neurosciences is to explain why herpes simplex encephalitis and semantic dementia show, respectively, a[ncbi.nlm.nih.gov]

  • Kearns-Sayre Syndrome

    We describe extensive white matter changes with abnormal signal intensity lesions involving the deep gray nuclei and myelinated white matter tracts in an 18-year-old female[ncbi.nlm.nih.gov] Occasionally, it is combined with other neurologic and endocrinologic symptoms such as ataxia, dementia, diabetes, and hyperaldosteronism.[ncbi.nlm.nih.gov] Brain MRI showed changes involving both the white matter and deep gray nuclei.[ncbi.nlm.nih.gov]

  • Subacute Sclerosing Panencephalitis

    Cognitive and behavioral decline was preceeded by 6-18 months in two children with intractable focal motor seizures with secondary generalization, one child with complex partial[ncbi.nlm.nih.gov] Later, high signal changes in deep white matter and severe cerebral atrophy were observed.[doi.org] Onset of dementia before 65 years of age is termed as young-onset dementia (YOD).[ncbi.nlm.nih.gov]

  • Tay-Sachs Disease

    MRI MRI is superior to CT in delineating deep white matter demyelination. Thalami may show changes consistent with calcification, best seen on T2* weighted sequences.[radiopaedia.org] Patient declines to dementia with seizures, with death by age 16 years.[patient.info] With MRI, deep white matter demyelination may be prominent; thalami may show changes consistent with calcification. No abnormal contrast enhancement is described 1-5.[radiopaedia.org]

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