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27 Possible Causes for Deep White Matter Changes, Dementia, Impaired Judgement

  • Alcohol Dementia

    […] logical thinking on tasks which require planning, organising, common sense judgement and social skills Problems with balance Decreased initiative and spontaneity.[dementiagippsland.com.au] The CT showed prominent sulci and gyri with deep white matter changes. There were no other abnormalities.[gponline.com] All about dementia types of dementia risk factors for dementia causes of dementia symptoms of dementia diagnosis of dementia dementia treatments long term dementia care alcohol-related[neurology.health-cares.net]

  • Stroke

    Early features include: loss of grey-white matter differentiation, and hypoattenuation of deep nuclei: lentiform nucleus changes seen as early as 1 hour after occlusion, visible[radiopaedia.org] Stroke is a strong, independent, and potentially modifiable risk factor for all-cause dementia.[ncbi.nlm.nih.gov] We increase understanding of the causes of cerebrovascular disease and improve the prevention of stroke and vascular dementia in routine clinical practice.[ndcn.ox.ac.uk]

  • Multi-Infarct Dementia

    Insight and judgement may be relatively well preserved.[azpsychiatry.info] Several pathogenic mechanisms appear implicated in the causation the deep white matter changes of Binswanger's disease, and hypoxia-ischemia resulting from watershed injury[web.archive.org] Mixed dementia consists of a combination between multi-infarct and Alzheimer's dementia.[symptoma.com]

  • Dementia

    Common dementia signs and symptoms Memory loss Impaired judgement Difficulties with abstract thinking Faulty reasoning Inappropriate behavior Loss of communication skills[helpguide.org] It may be particularly related to frontal deep white matter lesions. 16 Cognitive and behavioral changes in SVD are due to disruption of the frontal cortico-subcortical circuit[doi.org] […] as a public health priority; increasing awareness of dementia and establishing dementia-friendly initiatives; reducing the risk of dementia; diagnosis, treatment and care[who.int]

  • Normal Pressure Hydrocephalus

    White matter changes (WMC) INPH is known to be associated with deep white matter changes (DWMC) and smooth periventricular hyperintensity (PVH) [ 51 ] on MRI ( Figure 2B )[intechopen.com] Frequency 6 – 10 % of all dementia patients.[alzheimer-europe.org] White-matter changes: A distinction is drawn between periventricular and “deepwhite matter changes ( e49, e50 ); only the former are considered a sign of NPH.[ncbi.nlm.nih.gov]

  • Metabolic Encephalopathy

    white matter changes may be seen, with the appearance of hyperintensity on T2 sequences in the region of internal capsule, corona radiata, and splenium of corpus callosum[neurologyindia.com] The neurological disease complex associated with virus infection occurs in a large proportion of infected patients and is commonly referred to as HIV-1 associated dementia[ncbi.nlm.nih.gov] Infection of the nervous system by HIV-1 commonly causes a broad range of cognitive, behavioral, and motor abnormalities called, in its most severe form, HIV-1-associated dementia[ncbi.nlm.nih.gov]

  • Huntington's Disease

    Both deep grey matter and to a lesser degree white matter are involved in HD.[radiopaedia.org] Dementias: Advances in Neurology. 38 Vol. New York, NY: Raven; 1983. Meiser B, Dunn S.[web.archive.org] Dementias: Advances in Neurology. New York, NY: Raven; 1983. 38 Vol: Meiser B, Dunn S.[emedicine.medscape.com]

  • Creutzfeldt Jakob Disease

    Some other features, such as the presence of abnormal hyperintensity in the periaqueductal gray matter and posterior deep white matter tracts, were also common, and although[ajnr.org] Abstract Creutzfeldt-Jakob disease (CJD) is a rare prion disease that leads to a rapidly progressive dementia (RPD) and associated neurological features.[ncbi.nlm.nih.gov] We report a case of rapidly evolving neurological disease in a patient with neuropathological lesions of Creutzfeldt-Jakob disease (CJD), Lewy body dementia (LBD), chronic[ncbi.nlm.nih.gov]

  • Subacute Sclerosing Panencephalitis

    Later, high signal changes in deep white matter and severe cerebral atrophy were observed.[doi.org] Onset of dementia before 65 years of age is termed as young-onset dementia (YOD).[ncbi.nlm.nih.gov] Brain scans may be normal in the early phase, but eventually some changes affecting certain parts of the brain (the cerebral cortex, deep nuclei and white matter) can be detected[encephalitis.info]

  • Bipolar Disorder

    It affects memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement.[who.int] white matter abnormalities in individuals with BD ( Vederine et al. 2011 ; Torgerson et al. 2012).[ncbi.nlm.nih.gov] However, in some cases, dementia is caused by a non-neurodegenerative disease, such as an affective disorder. In these cases, the dementia can be reversible.[ncbi.nlm.nih.gov]

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