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27 Possible Causes for Deep White Matter Changes, Dementia, Rhythmic Slowing

  • Stroke

    Early features include: loss of grey-white matter differentiation, and hypoattenuation of deep nuclei: lentiform nucleus changes seen as early as 1 hour after occlusion, visible[radiopaedia.org] Rhythmic slow discharges in the electroencephalogram. J Neurol Neurosurg Psychiatry 1945;8:65. [ Links ] 19. Faure J, Droogleever-Fortuyn, Gastaut H.[scielo.br] Stroke is a strong, independent, and potentially modifiable risk factor for all-cause dementia.[ncbi.nlm.nih.gov]

  • Metabolic Encephalopathy

    white matter changes may be seen, with the appearance of hyperintensity on T2 sequences in the region of internal capsule, corona radiata, and splenium of corpus callosum[neurologyindia.com] The neurological disease complex associated with virus infection occurs in a large proportion of infected patients and is commonly referred to as HIV-1 associated dementia[ncbi.nlm.nih.gov] Infection of the nervous system by HIV-1 commonly causes a broad range of cognitive, behavioral, and motor abnormalities called, in its most severe form, HIV-1-associated dementia[ncbi.nlm.nih.gov]

  • Dementia

    It may be particularly related to frontal deep white matter lesions. 16 Cognitive and behavioral changes in SVD are due to disruption of the frontal cortico-subcortical circuit[doi.org] […] as a public health priority; increasing awareness of dementia and establishing dementia-friendly initiatives; reducing the risk of dementia; diagnosis, treatment and care[who.int] Memory loss is a common symptom of dementia. However, memory loss by itself does not mean you have dementia.[web.archive.org]

  • Toxic Encephalopathy

    white matter changes may be seen, with the appearance of hyperintensity on T2 sequences in the region of internal capsule, corona radiata, and splenium of corpus callosum[neurologyindia.com] , and alcoholic dementia.[ncbi.nlm.nih.gov] What Is Dementia From Toxic Substances?[dementia.org]

  • Hyponatremia

    In the brain MRI, millimeter-sized chronic microangiopathic ischemic signal changes were observed in the periventricular deep white matter; no mass image was seen in the pituitary[reumatologiaclinica.org] Independent of adjusting factors, hyponatremia patients had 2.36-fold higher chances of suffering dementia, including Alzheimer's disease (AD) and non-AD dementia, than the[ncbi.nlm.nih.gov] Stroke is notorious for doubling the risk of suffering dementia (post-stroke dementia), including both AD and non-AD dementia[ 37 ].[journals.plos.org]

  • Meningoencephalitis

    Nevertheless, autopsy of the patient revealed frank ischemic changes (subacute infarcts) in the deep hemispheric white matter ( Fig 3 G ).[ajnr.org] An EEG showed moderate diffuse background slowing and frequent runs of frontally predominant rhythmic delta waves consistent with seizure activity.[jamanetwork.com] We illustrated a 53-year-old man diagnosed with dementia. Neuroimaging and cerebrospinal fluid studies disclosed meningoencephalitis.[ncbi.nlm.nih.gov]

  • Normal Pressure Hydrocephalus

    White matter changes (WMC) INPH is known to be associated with deep white matter changes (DWMC) and smooth periventricular hyperintensity (PVH) [ 51 ] on MRI ( Figure 2B )[intechopen.com] In 13 cases the EEG was abnormal, the abnormality most frequently observed being a of the rhythmic slow wave type, consisting of bursts of monorhythmic theta or delta waves[link.springer.com] Frequency 6 – 10 % of all dementia patients.[alzheimer-europe.org]

  • Diffuse Cerebral Sclerosis of Schilder

    change in the deep white matter.[doi.org] Sequential EEG studies: show progressive deterioration in background organisation, with predominantly high-voltage irregular slowing.[patient.info] The clinical course tends to be progressive and includes dementia, cortical blindness, cortical deafness, spastic hemiplegia, and pseudobulbar palsy.[icd9data.com]

  • Herpes Simplex Encephalitis

    The frontal dysexecutive syndrome and personality change could be explained by the involvement of frontal lobe white matter and the sensory symptoms, diplopia, and increased[jamanetwork.com] […] with the patient’s rhythmic lip smacking movements.[karger.com] Abstract A very challenging problem in the domain of the cognitive neurosciences is to explain why herpes simplex encephalitis and semantic dementia show, respectively, a[ncbi.nlm.nih.gov]

  • Subacute Sclerosing Panencephalitis

    Later, high signal changes in deep white matter and severe cerebral atrophy were observed.[doi.org] ., high-voltage slow-wave complexes interspersed with short rhythmic waves) [Figure 1].[ijpm.info] Onset of dementia before 65 years of age is termed as young-onset dementia (YOD).[ncbi.nlm.nih.gov]

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