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60 Possible Causes for Deep White Matter Changes, Pyramidal Tract Signs

  • Stroke

    Early features include: loss of grey-white matter differentiation, and hypoattenuation of deep nuclei: lentiform nucleus changes seen as early as 1 hour after occlusion, visible[radiopaedia.org]

  • Primary Progressive Multiple Sclerosis

    Consistent with this reduction, we showed that changes in diffusion indices of tissue damage within major clinically relevant white matter (corpus callosum and corticospinal[ncbi.nlm.nih.gov] […] tract) and deep grey matter (thalamus) structures were significantly reduced during the treatment phase (P 0.02, corrected).[ncbi.nlm.nih.gov]

  • Binswanger Disease

    OBJECTIVES: To analyse the diagnostic and prognostic value of periventricular hyperintensity (PVH) and deep white matter hyperintensity (DWMH) magnetic resonance imaging ([ncbi.nlm.nih.gov] The GFAP and MT-I-II expressions in subsets of reactive astrocytes in the cortico-subcortical layers together with regressive astroglial changes in the deep white matter suggest[content.iospress.com] white-matter of the brain, loss of memory and cognition, and mood changes.[prep4usmle.com]

  • Hallervorden-Spatz Syndrome

    Table-1: Diagnostic features of Hallervorden spatz disease [11] Obligate Features Collaborate Features Exclusion Features Onset during first two decades Pyramidal tract signs[medresearch.in] Brain stem nuclei had similar changes. The high signal intensity lesions in the deep cerebral white matter and dentate nuclei were unchanged.[ajnr.org] tract signs. 1 Choreoathetotic movements or tremor may also be present but these features have not been described in isolation.[jnnp.bmj.com]

  • Marchiafava Bignami Disease

    Type A: acute to subacute onset of consciousness impairment, pyramidal tract signs, limb hypertonia, seizures, hyperintense swelling of the corpus callosum on T2-weighted[jcdr.net] white matter microstructural changes on MRI in relation to early-stage atherosclerosis.[med.u-fukui.ac.jp] Radiology has helped to identify two subgroups: Type A is characterised by coma, stupor and pyramidal tract features.[patient.info]

  • Infantile Neuroaxonal Dystrophy

    tract signs, marked hypotonia and early visual disturbances without epileptic seizures.[ncbi.nlm.nih.gov] In one patient (juvenile case) with lesions in the deep frontal white matter, an elevated diffusion pattern was evident.[ajnr.org] tract signs.[cags.org.ae]

  • Subacute Sclerosing Panencephalitis

    Later, high signal changes in deep white matter and severe cerebral atrophy were observed.[doi.org] Brain scans may be normal in the early phase, but eventually some changes affecting certain parts of the brain (the cerebral cortex, deep nuclei and white matter) can be detected[encephalitis.info] Diffusion weighted change on MRI may be associated with the white matter lesions [ 19 ] but there is little evidence currently.[ncbi.nlm.nih.gov]

  • Pineal Gland Cyst

    Pineal tumors also, but infrequently, present with cerebellar ataxia due to a compression of the superior cerebellar peduncle, and pyramidal tract signs.[plaza.umin.ac.jp] Today I received my results stating I have a few like foci of increased T2 signal in the deep periventricular white matter regions.[healthcaremagic.com] These are compatible with ischemic/gliotic changes, or could represent the sequela of migraine headaches. It also states I have a small simple pineal cyst ...[healthcaremagic.com]

  • Alexander Disease

    We report a case of genetically confirmed adult-onset AD with palatal myoclonus, pyramidal tract signs, cerebellar signs, and marked atrophy of the medulla oblongata and spinal[ncbi.nlm.nih.gov] Brain magnetic resonance imaging (MRI) showed atrophy of the medulla oblongata and mild cervical cord atrophy, deep white matter abnormalities, periventricular rim, and signal[ncbi.nlm.nih.gov] Adults may present with bulbar/pseudobulbar signs, pyramidal tract signs, cerebellar signs, dysautonomia, sleep disturbance, gait disturbance, hemiparesis/hemiplegia or quadriparesis[ncbi.nlm.nih.gov]

  • Demyelinating Disease

    The examination revealed bilateral optic neuritis with multiple left cranial nerve palsy (IX, X and XII), bilateral pyramidal tract signs (more prominent on the right side[jmedicalcasereports.com] white matter ischemia radiotherapy changes[radiopaedia.org] white matter ischemia radiotherapy changes Related Radiopaedia articles Promoted articles (advertising)[radiopaedia.org]

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