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50 Possible Causes for Deeply Grooved Philtrum

  • Legius Syndrome

    Noonan like features include congenital heart problems, hyperextensibility, low muscle tone, low set and posteriorly rotated ears, deeply grooved philtrum, wide spaced eyes[inspire.com]

  • Noonan Syndrome

    grooved philtrum High wide peaks to vermillion border of upper lip Excess nuchal skin and low posterior hairline Children [ edit ] Facial appearance lacks expression (resembles[en.wikibooks.org] grooved philtrum (top lip line), high arched palate Excess skin in the back of the neck, low hairline at the nape of the neck High hairline at the front of the head, curly[dovemed.com] grooved philtrum Hypertelorism : Widely spaced eyes Depressed nasal bridge Down -slanting palpebral fissures Low set ears, posteriorly rotated High arched palate Misalignment[pedclerk.bsd.uchicago.edu]

  • Watson Syndrome

    grooved philtrum with high arched palate of the upper lip vermilion border (GSA), high arched palate (45%), micrognathia (25%), excess nuchal skin with low posterior hair[indianpediatrics.net] grooved philtrum High wide peaks to vermillion border of upper lip Excess nuchal skin and low posterior hairline Children [ edit ] Facial appearance lacks expression (resembles[en.wikibooks.org] Clinical features involve head and neck (macrocephaly, short neck, hypertelorism, broad forehead, down-slanted fissures, ptosis, puffy eyelids, triangular face, deeply grooved[accessanesthesiology.mhmedical.com]

  • Noonan Syndrome-Like Disorder with Juvenile Myelomonocytic Leukemia

    grooved philtrum (upper lip line) Learning delays Genetics [ edit ] About 90% of JMML patients have some sort of genetic abnormality in their leukemia cells that can be identified[en.wikipedia.org] grooved philtrum (top lip line) (over 90%) Micrognathia (undersized lower jaw) High arched palate Dental problems Articulation difficulties Poor tongue control Limbs/extremities[en.wikipedia.org] Undescended testicles in males Excess skin and low hair line on back of neck Widely set eyes Diamond-shaped eyebrows Ears that are low-set, backward-rotated, thick outer rim Deeply[en.wikipedia.org]

  • Disproportionate Short Stature - Ptosis - Valvular Heart Lesions

    grooved philtrum Hypertelorism : Widely spaced eyes Depressed nasal bridge Down -slanting palpebral fissures Low set ears, posteriorly rotated High arched palate Misalignment[pedclerk.bsd.uchicago.edu] grooved philtrum (top lip line) (over 90%) Micrognathia (undersized lower jaw) High arched palate Dental problems Articulation difficulties Poor tongue control Limbs/extremities[en.wikipedia.org] Syndrome - Short stature (50 – 70%) Normal birth weight and height Decreased height velocity in the first year of life Thought to be caused by low levels of growth hormone Deeply[pedclerk.bsd.uchicago.edu]

  • Congenital Mandibular Hypoplasia

    grooved philtrum, micrognathia, high arched palate ROEDEMA: oedema of hands/feet (early) STATURE: short, pectus excavatum, winging of scapula HEAD: excess skin on nape, low[quizlet.com] […] pathways on different genes (70%) - not same gene, therefore CLINICAL DIAGNOSIS 1 in 1,000 (similar to Tri 21) AKA Turner's for boys Feats: - Physical (MR SHEEN) MOUTH: deeply[quizlet.com]

  • Blepharofacioskeletal Syndrome

    She had a long face, broad forehead with a high anterior hairline, anteverted and prominent ears, malar hypoplasia, a broad nasal tip and columella, deeply grooved philtrum[researchgate.net]

  • Leontiasis Ossium

    grooved philtrum with high arched palate of the upper lip vermilion border (GSA), high arched palate (45%), micrognathia (25%), excess nuchal skin with low posterior hair[indianpediatrics.net] […] typical facies is characterized by hypotelorism, down-slanting palpebral fissures (95%) with thick hooded eyelids, low set posteriorly rotated ears with a thick helix (90%), a deeply[indianpediatrics.net]

  • Polydactyly of a Biphalangeal Thumb

    Patients 1 and 2 have high and broad forehead, deeply grooved philtrum, thick anteverted lobes and thick helix.[pubfacts.com]

  • Branchio-Oculo-Facial Syndrome

    deeply grooved - Protruding lips - Retinoschisis / retinal / chorioretinal coloboma - Skin hypoplasia / aplasia / atrophy Frequent - Abnormal cry / voice / phonation disorder[csbg.cnb.csic.es] […] port-wine stain - Conductive deafness / hearing loss - Dermoid sinus / dimple / pit (excluding sacral) - External ear anomalies - Low set ears / posteriorly rotated ears - Philtrum[csbg.cnb.csic.es]

Further symptoms