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186 Possible Causes for Degeneration of Epidermal Basal Cells, Discoid Rash

  • Systemic Lupus Erythematosus

    Malar rash – a rash over the cheeks and nose, often in the shape of a butterfly Discoid rash – a rash that appears as red, raised, disk-shaped patches Photosensitivity – a[web.archive.org] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[medical-dictionary.thefreedictionary.com] Symptoms may include: malar rash- a rash shaped like a butterfly that is usually found on the bridge of the nose and the cheeks. discoid rash- a raised rash found on the head[web.archive.org]

  • Discoid Lupus Erythematosus

    Other symptoms of discoid lupus include change in skin pigment or color and hair loss. The discoid rash is non-itchy, raised and scaly.[empowher.com] A skin biopsy from her cheek revealed hyperkeratosis, focal epidermal atrophy, basal cell degeneration and dilated follicular orifices filled with compact keratin.[ncbi.nlm.nih.gov] […] membrane (best demonstrated by periodic acid-Schiff staining) and vacuolar degeneration of the basal cells along with perivascular and peri-appendageal inflammatory cell[doi.org]

  • Lupus Erythematosus

    (discoid rash) Rash resulting from sensitivity to the sun (photosensitivity) Ulcers in the nose or mouth Two or more joints affected by arthritis with swelling, tenderness[emedicinehealth.com] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[medical-dictionary.thefreedictionary.com] Discoid rash Erythematous raised patches with adherent keratotic scaling and follicular plugging; atrophic scarring may occur in older lesions 3.[pedclerk.bsd.uchicago.edu]

  • Tinea Corporis

    BACKGROUND: Tinea corporis gladiatorum has been an infrequently reported condition in the dermatological literature. Two previous reports have investigated wrestlers during recognized epidemics of tinea corporis gladiatorum, but no study has examined wrestlers to determine the point prevalence of tinea corporis[…][ncbi.nlm.nih.gov]

    Missing: Degeneration of Epidermal Basal Cells
  • Chilblain Lupus Erythematosus

    Most common presenting symptoms Skin ( 70% of cases) Malar rash (“ butterfly rash ”) with sparing of the nasolabial folds Photosensitivity Discoid rash Oral ulcers Joints[amboss.com] In particular, skin histopathology of DLE shows classical features: vacuolar degeneration of basal cell layer; thickened basement membrane; orthokeratosis with follicular[ped-rheum.biomedcentral.com] . • Skin disease is the second most frequent clinical manifestation of LE 1 malar rash 2 discoid rash 3 photosensitivity 4 oral ulcers 5 arthritis 6 serositis 7 renal disorder[slideshare.net]

  • Pediatric Systemic Lupus Erythematosus

    Transient features include photosensitive discoid rash, cytopenia, hepatosplenomegaly, myocarditis, and pericarditis; the permanent features include congenital complete heart[ncbi.nlm.nih.gov] […] and flare of other organ involvement Lupus can affect any organ 1997 ACR SLE Criteria • • • • • Malar Rash Discoid Rash Photosensitivity Oral/nasal ulcers Non-erosive arthritis[slideblast.com] Discoid rash Erythematous raised patches with adherent keratotic scaling and follicular plugging; atrophic scarring may occur in older lesions 3.[pedclerk.bsd.uchicago.edu]

    Missing: Degeneration of Epidermal Basal Cells
  • Photosensitivity Disorder

    Systemic lupus erythematosus is characterized by photosensitivity, malar rash, and discoid lupus erythematosus like skin lesions which can be aggravated in tropical climate[ijdvl.com] Microscopic evaluation revealed epidermal erosion and ulceration, with severe epidermal basal cell degeneration and necrosis, and superficial dermatitis (python and skink)[ncbi.nlm.nih.gov]

  • Tuberculid

    […] and malar rash, photosensitivity, coarse speckled nuclear antinuclear antibody and thrombocytopenia.[scielo.br] The earlobe biopsy showed epidermal hyperkeratosis and parakeratosis, liquefaction degeneration of the basal cells, and follicular keratotic plugging, and the blood vessels[cmj.yiigle.com] Focal lymphocytic infiltrate and focal vacuolar degeneration of the basal cell layer were seen at the dermal-epidermal junction.[cyberleninka.org]

  • Cutaneous Lupus Erythematosus

    (n 2 [15%]), oral ulcers (n 2 [15%]), and discoid rash (n 1 [8%]).[archderm.jamanetwork.com] Of the 13 patients, 1 (8%) solely met the ACR criteria because of malar rash, discoid rash, photosensitivity, and oral ulcers, and 3 (23%) met the ACR criteria for malar rash[archderm.jamanetwork.com] Almost 25% did not have any other criteria aside from photosensitivity, malar rash, discoid rash, oral ulcers, and positive ANA and other antibody titers.[archderm.jamanetwork.com]

    Missing: Degeneration of Epidermal Basal Cells
  • Erythema Annulare Centrifugum

    The differential diagnosis of EAC includes subacute cutaneous lupus, discoid lupus, erythema migrans, pityriasis rosea, tinea corporis and erythema multiforme.[clinicaladvisor.com] Histopathology demonstrates epidermal atrophy, basal cell degeneration, and mononuclear cell infiltrate in the dermis.[ijpd.in] With malignancy, however, the course of EAC tends to parallel that of the underlying cancer, with rash resolution occurring with tumor suppression and recurring with relapse[clinicaladvisor.com]

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