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39 Possible Causes for Degeneration of Epidermal Basal Cells, Eosinophilia

  • Systemic Lupus Erythematosus

    In rare cases, pleural eosinophilia is associated with connective tissue disease.[] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[] A thoracocentesis revealed an exudate with eosinophilia. Direct cytological examination showed LE cells. SLE was rapidly considered.[]

  • Erythema Multiforme

    […] cytopenia, vasculitis, acute allergic interstitial nephritis, occupational contact dermatitis, photoallergic dermatitis, maculopapular eruption, erythroderma, Drug rash with eosinophilia[] Pathologic findings include liquefactive degeneration of the basal epidermal cells, necrotic keratinocytes, and exocytosis of lymphocytes.[] Histologic Features: Basal cell hydropic degeneration, which may be severe enough to result in the formation of subepidermal clefts or vesicles Apoptosis of keratinocytes,[]

  • Vasculitis

    All serologic studies were normal except for increased levels of rheumatoid factor and eosinophilia.[] There is sparse scattered lymphocytic infiltration centred around the basal layer /- vacuolar degeneration of the basal layer.[] Anaemia, Leukocytosis, Eosinophilia. Antineutrophil cytoplasmic antibodies (ANCA). Elevated factor VIII - related antigen (von Willebrand factor).[]

  • Pityriasis Circinata

    In the drug induced form there is no herald patch, individual lesions tend to be violet-red in colour, pruritus is more severe, and eosinophilia may be present.[] Besides, histology shows epidermal atrophy and basal layer degeneration.[] Rarely, primary HIV infection, seborrhoeic dermatitis, drug rash, erythema multiforme and cutaneous T cell lymphoma may also be confused with PR.[]

  • Erythema Annulare Centrifugum

    Histopathology demonstrates epidermal atrophy, basal cell degeneration, and mononuclear cell infiltrate in the dermis.[] A 65-year-old male presented with a history of disseminated erythema annulare centrifugum lesions and a high peripheral blood eosinophilia (55%).[] The skin lesions cleared within one month but the pruritus and eosinophilia required seven full months of therapy.[]

  • Graft-versus-Host-Disease

    But other patients with chronic GVHD never have eosinophilia, so the lack of eosinophilia does not influence the diagnosis of chronic GVHD.[] Skin biopsies were consistent with GVHD, showing vacuolar degeneration of the basal layer of the epithelium, epidermal infiltration by lymphocytes and necrotic eosinophilic[] Eosinophilia correlates with the presence or development of chronic graft-versus-host disease in children . Transplantation 2004; 77 : 1096–1100. 32.[]

  • Bazex Syndrome

    […] and never of mesodermal origin, possible histopathological changes including the presence of necrotic foci, scattered vacuolar degeneration of basal cells, cytoplasmic eosinophilia[] The mild eosinophilia subsided and levels of SCC antigen, IgE, and soluble interleukin-2 receptor were reduced.[] […] where the pathomechanism of Acrotkeratosis paraneoplastica may be related to an immunological reaction as indicated by multiple factors: association with tumours always of epidermal[]

  • Lupus Erythematosus

    Other diagnoses included in these codes but without sufficient sample sizes to analyze individually are Felty’s syndrome, eosinophilia myalgia syndrome, juvenile chronic polyarthritis[] […] of basal cells; 4) a predominantly lymphocytic infiltrate along the dermal-epidermal junction, around the fair follicles and eccrine ducts, in an interstitial pattern; 14[] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[]

  • Junctional Epidermolysis Bullosa

    To our knowledge, our patient is the first with JEB-nH to be treated successfully with an oral steroid to control his skin affliction, symptoms and eosinophilia.[] […] layer caused by degeneration of individual epidermal cells Dystrophic EB: pretibial lesion Electron microscopy description Electron microscopy images Images hosted on other[] This suggests that in the case of JEB-nH with eosinophilia caused by some secondary immune activation, oral steroids may constitute an alternate therapy to improve aggravated[]

  • Lichen Simplex Chronicus

    The infection produces peripheral eosinophilia and cutaneous eruptions, as well as gastrointestinal or respiratory symptoms.[] Moreover, basal cell degeneration is confined to tips of rete ridges and band like infiltration is conspicuously absent in HLP.[] In some areas, the cells of the prickle cell layer exhibited increased eosinophilia.[]

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