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37 Possible Causes for Degeneration of Epidermal Basal Cells, Eosinophilia, Eosinophils Increased

  • Systemic Lupus Erythematosus

    In rare cases, pleural eosinophilia is associated with connective tissue disease.[ncbi.nlm.nih.gov] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[medical-dictionary.thefreedictionary.com] A thoracocentesis revealed an exudate with eosinophilia. Direct cytological examination showed LE cells. SLE was rapidly considered.[ncbi.nlm.nih.gov]

  • Erythema Multiforme

    […] cytopenia, vasculitis, acute allergic interstitial nephritis, occupational contact dermatitis, photoallergic dermatitis, maculopapular eruption, erythroderma, Drug rash with eosinophilia[aaaai.org] Pathologic findings include liquefactive degeneration of the basal epidermal cells, necrotic keratinocytes, and exocytosis of lymphocytes.[onlinelibrary.wiley.com] Hydroxychloroquine was discontinued and the dose of prednisone was increased to 60 mg/day.[oatext.com]

  • Vasculitis

    All serologic studies were normal except for increased levels of rheumatoid factor and eosinophilia.[ncbi.nlm.nih.gov] There is sparse scattered lymphocytic infiltration centred around the basal layer /- vacuolar degeneration of the basal layer.[dermnetnz.org] The presence of asthma, peripheral blood eosinophilia with elevated IgE levels, pulmonary eosinophilia in BAL fluid, and the presence of eosinophils in tissue, make it unique[pulmonologyadvisor.com]

  • Pityriasis Circinata

    In the drug induced form there is no herald patch, individual lesions tend to be violet-red in colour, pruritus is more severe, and eosinophilia may be present.[doi.org] Besides, histology shows epidermal atrophy and basal layer degeneration.[ncbi.nlm.nih.gov] […] dermal eosinophils. [18] Nummular eczema Lesions are discrete, round, more likely to have generalized scale rather than collarette, usually xerotic. [3] [17] Clinical diagnosis[online.epocrates.com]

  • Erythema Annulare Centrifugum

    A 65-year-old male presented with a history of disseminated erythema annulare centrifugum lesions and a high peripheral blood eosinophilia (55%).[ncbi.nlm.nih.gov] Histopathology demonstrates epidermal atrophy, basal cell degeneration, and mononuclear cell infiltrate in the dermis.[ijpd.in] The skin lesions cleared within one month but the pruritus and eosinophilia required seven full months of therapy.[ncbi.nlm.nih.gov]

  • Graft-versus-Host-Disease

    But other patients with chronic GVHD never have eosinophilia, so the lack of eosinophilia does not influence the diagnosis of chronic GVHD.[cancertherapyadvisor.com] Skin biopsies were consistent with GVHD, showing vacuolar degeneration of the basal layer of the epithelium, epidermal infiltration by lymphocytes and necrotic eosinophilic[ncbi.nlm.nih.gov] Eosinophilia correlates with the presence or development of chronic graft-versus-host disease in children . Transplantation 2004; 77 : 1096–1100. 32.[nature.com]

  • Bazex Syndrome

    The mild eosinophilia subsided and levels of SCC antigen, IgE, and soluble interleukin-2 receptor were reduced.[obesity.thehealthwell.info] […] and never of mesodermal origin, possible histopathological changes including the presence of necrotic foci, scattered vacuolar degeneration of basal cells, cytoplasmic eosinophilia[bmccancer.biomedcentral.com] […] epidermal and never of mesodermal origin, possible histopathological changes including the presence of necrotic foci, scattered vacuolar degeneration of basal cells, cytoplasmic eosinophilia[bmccancer.biomedcentral.com]

  • Junctional Epidermolysis Bullosa

    To our knowledge, our patient is the first with JEB-nH to be treated successfully with an oral steroid to control his skin affliction, symptoms and eosinophilia.[ncbi.nlm.nih.gov] […] layer caused by degeneration of individual epidermal cells Dystrophic EB: pretibial lesion Electron microscopy description Electron microscopy images Images hosted on other[pathologyoutlines.com] Symptoms almost disappeared at the age of 3 years but reappeared with increased severity after 6 months.[ncbi.nlm.nih.gov]

  • Lichen Simplex Chronicus

    The infection produces peripheral eosinophilia and cutaneous eruptions, as well as gastrointestinal or respiratory symptoms.[ncbi.nlm.nih.gov] Moreover, basal cell degeneration is confined to tips of rete ridges and band like infiltration is conspicuously absent in HLP.[omicsonline.org] In some areas, the cells of the prickle cell layer exhibited increased eosinophilia.[jamanetwork.com]

  • Lupus Erythematosus

    Other diagnoses included in these codes but without sufficient sample sizes to analyze individually are Felty’s syndrome, eosinophilia myalgia syndrome, juvenile chronic polyarthritis[doi.org] […] of basal cells; 4) a predominantly lymphocytic infiltrate along the dermal-epidermal junction, around the fair follicles and eccrine ducts, in an interstitial pattern; 14[scielo.br] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[medical-dictionary.thefreedictionary.com]

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