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37 Possible Causes for Degeneration of Epidermal Basal Cells, Eosinophilia, Eruptions

  • Erythema Multiforme

    We report a case of an erythema multiforme drug eruption associated with erythrodermic psoriasis induced by SOF and DCV.[] […] cytopenia, vasculitis, acute allergic interstitial nephritis, occupational contact dermatitis, photoallergic dermatitis, maculopapular eruption, erythroderma, Drug rash with eosinophilia[] Pathologic findings include liquefactive degeneration of the basal epidermal cells, necrotic keratinocytes, and exocytosis of lymphocytes.[]

  • Pityriasis Circinata

    Gianotti-Crosti syndrome, pityriasis rosea, asymmetrical periflexural exanthem, unilateral mediothoracic exanthem, eruptive pseudoangiomatosis and papular-purpuric gloves[] In the drug induced form there is no herald patch, individual lesions tend to be violet-red in colour, pruritus is more severe, and eosinophilia may be present.[] Besides, histology shows epidermal atrophy and basal layer degeneration.[]

  • Systemic Lupus Erythematosus

    We postulate that this eruption was related to SLE and anticardiolipin antibodies.[] In rare cases, pleural eosinophilia is associated with connective tissue disease.[] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[]

  • Erythema Annulare Centrifugum

    EAC with cancers or paraneoplastic erythema annulare centrifugum eruptions (PEACE), is more likely to be associated with lymphoproliferative malignancies such as lymphomas[] Histopathology demonstrates epidermal atrophy, basal cell degeneration, and mononuclear cell infiltrate in the dermis.[] A 65-year-old male presented with a history of disseminated erythema annulare centrifugum lesions and a high peripheral blood eosinophilia (55%).[]

  • Actinic Lichen Planus

    , polymorphous light eruption, and erythema dyschronicum perstans. 5 The clinician also must exclude the possibility of a drug-induced photosensitive lichenoid eruption by[] Carcinoma Bowen's Disease Chronic Actinic Skin Damage Cornu Cutaneum Discoid Lupus Erythematosus (DLE) Disseminated Superficial Actinic Porokeratosis Facial Granuloma with Eosinophilia[] Histology classically demonstrates hyperkeratosis, epidermal thinning, vacuolar degeneration of the basal cell layer, lymphohistiocytic band-like infiltrate, variable Civatte[]

  • Photosensitivity Disorder

    Polymorphous light eruption This eruption is a reaction to sunlight (primarily UVA light) that is not fully understood.[] The syndrome typically includes skin rash and fever, often with hepatitis, arthralgias, lymphadenopathy, or haematological disorders (mainly eosinophilia and atypical lymphocytosis[] Microscopic evaluation revealed epidermal erosion and ulceration, with severe epidermal basal cell degeneration and necrosis, and superficial dermatitis (python and skink)[]

  • Bullous Lichen Planus

    There were significant differences between familial and non-familial BLP in age of onset, duration of disease and extension of eruption (P[] Degeneration of basal epidermal cells leads to exposure of the basement membrane antigens.[] Histopathology showed a subepidermal blistering disease with tissue eosinophilia consistent with lichen planus pemphigoides (LPP)(Figure 2); direct immunofluorescence was[]

  • Vasculitis

    Drug eruption was been confirmed by means of a challenge test, together with histopathological and clinical findings.[] All serologic studies were normal except for increased levels of rheumatoid factor and eosinophilia.[] There is sparse scattered lymphocytic infiltration centred around the basal layer /- vacuolar degeneration of the basal layer.[]

  • Chronic Lichenoid Pityriasis

    […] diseases characterized by the formation of fine, branny scales. acute lichenoid pityriasis an acute or subacute, sometimes relapsing, widespread macular, papular, or vesicular eruption[] Acquired digital fibrokeratoma Angiolymphoid hyperplasia with eosinophilia vs. Angiosarcoma Angiolymphoid hyperplasia with eosinophilia vs.[] Epidermal changes include spongiosis and, characteristically, vacuolar degeneration of stratum basale. [22] Lymphocytic exocytosis into the epidermis is seen in EM as also[]

  • Bazex Syndrome

    Bazex syndrome, a rare paraneoplastic syndrome characterized by psoriasiform eruptions, palmoplantar keratosis, and symmetric onychodystrophy, is most prevalent with squamous[] […] and never of mesodermal origin, possible histopathological changes including the presence of necrotic foci, scattered vacuolar degeneration of basal cells, cytoplasmic eosinophilia[] The mild eosinophilia subsided and levels of SCC antigen, IgE, and soluble interleukin-2 receptor were reduced.[]

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