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25 Possible Causes for Degeneration of Epidermal Basal Cells, Eosinophilia, Erythema Multiforme

  • Systemic Lupus Erythematosus

    However, some mothers taking MMF were being treated for immune-mediated conditions such as systemic lupus erythematosus (SLE) and erythema multiforme.[] In rare cases, pleural eosinophilia is associated with connective tissue disease.[] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[]

  • Erythema Multiforme

    , erythema multiforme type Febrile mucocutaneous syndrome Erythema multiforme bullosum Dermatostomatitis, erythema multiforme type Erythema polymorphe, erythema multiforme[] […] cytopenia, vasculitis, acute allergic interstitial nephritis, occupational contact dermatitis, photoallergic dermatitis, maculopapular eruption, erythroderma, Drug rash with eosinophilia[] Pathologic findings include liquefactive degeneration of the basal epidermal cells, necrotic keratinocytes, and exocytosis of lymphocytes.[]

  • Pityriasis Circinata

    Erythema multiforme. Pityriasis versicolor. Pityriasis lichenoides. Tinea corporis. Discoid (nummular) eczema. Seborrhoeic dermatitis. Drug eruptions. Erythema migrans.[] In the drug induced form there is no herald patch, individual lesions tend to be violet-red in colour, pruritus is more severe, and eosinophilia may be present.[] Besides, histology shows epidermal atrophy and basal layer degeneration.[]

  • Erythema Annulare Centrifugum

    NOS Erythroderma NOS annulare L53.1 (centrifugum) (rheumaticum) ICD-10-CM Codes Adjacent To L53.1 L51 Erythema multiforme L51.0 Nonbullous erythema multiforme L51.1 Stevens-Johnson[] A 65-year-old male presented with a history of disseminated erythema annulare centrifugum lesions and a high peripheral blood eosinophilia (55%).[] Histopathology demonstrates epidermal atrophy, basal cell degeneration, and mononuclear cell infiltrate in the dermis.[]

  • Bullous Lichen Planus

    Histologically, erythema multiforme shares common features with lichenoid reactions, such as necrotic keratinocytes.[] Histopathology showed a subepidermal blistering disease with tissue eosinophilia consistent with lichen planus pemphigoides (LPP)(Figure 2); direct immunofluorescence was[] Degeneration of basal epidermal cells leads to exposure of the basement membrane antigens.[]

  • Chilblain Lupus Erythematosus

    Transformation to systemic LE occurs more often in those who develop both forms of cutaneous LE simultaneously and in the erythema multiforme syndrome.[] Blood tests: FBC may show raised white count/eosinophilia or lymphopenia. Anaemia may be seen. ESR is often raised ( 65% of cases).[] In particular, skin histopathology of DLE shows classical features: vacuolar degeneration of basal cell layer; thickened basement membrane; orthokeratosis with follicular[]

  • Chronic Lichenoid Pityriasis

    PR with erythema multiforme (EM)-like lesions is a very rarely reported variant.[] Acquired digital fibrokeratoma Angiolymphoid hyperplasia with eosinophilia vs. Angiosarcoma Angiolymphoid hyperplasia with eosinophilia vs.[] […] in only 3-7% of patients, with some cases featuring Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, or ‘drug rash with eosinophilia[]

  • Vasculitis

    multiforme, Mucha-Habermann disease, some viral infections, collagen vascular disease, PLEVA and erythema multiforme Fibrin thrombi: present in segmented, hyalinizing vasculitis[] All serologic studies were normal except for increased levels of rheumatoid factor and eosinophilia.[] There is sparse scattered lymphocytic infiltration centred around the basal layer /- vacuolar degeneration of the basal layer.[]

  • Erythema Marginatum

    . #4 Erythema multiforme: Usu. drug reactions.[] Another patient experienced exacerbations of EAC premenstrually as a type of autoimmune progesterone dermatitis. [27] Hypereosinophilic syndrome: A patient with 31% eosinophilia[] Histopathology demonstrates epidermal atrophy, basal cell degeneration, and mononuclear cell infiltrate in the dermis.[]

  • Actinic Lichen Planus

    The incidence of erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis.[] Carcinoma Bowen's Disease Chronic Actinic Skin Damage Cornu Cutaneum Discoid Lupus Erythematosus (DLE) Disseminated Superficial Actinic Porokeratosis Facial Granuloma with Eosinophilia[] Histology classically demonstrates hyperkeratosis, epidermal thinning, vacuolar degeneration of the basal cell layer, lymphohistiocytic band-like infiltrate, variable Civatte[]

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