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13 Possible Causes for Degeneration of Epidermal Basal Cells, Eosinophilia, Exanthema

  • Systemic Lupus Erythematosus

    A 42-year-old woman was admitted to our hospital with complaints of exanthema, arthralgia, shortness of breath, and hemoptysis.[ncbi.nlm.nih.gov] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[medical-dictionary.thefreedictionary.com] In rare cases, pleural eosinophilia is associated with connective tissue disease.[ncbi.nlm.nih.gov]

  • Erythema Multiforme

    […] skin syndrome, Impetigo, Boil, Carbuncle ) · Strep ( Impetigo ) · Corynebacterium ( Erythrasma ) Viral skin disease Wart · Molluscum contagiosum · Erythema infectiosum · Exanthema[wikidoc.org] Pathologic findings include liquefactive degeneration of the basal epidermal cells, necrotic keratinocytes, and exocytosis of lymphocytes.[onlinelibrary.wiley.com] […] cytopenia, vasculitis, acute allergic interstitial nephritis, occupational contact dermatitis, photoallergic dermatitis, maculopapular eruption, erythroderma, Drug rash with eosinophilia[aaaai.org]

  • Vasculitis

    All serologic studies were normal except for increased levels of rheumatoid factor and eosinophilia.[ncbi.nlm.nih.gov] […] disease include fever lasting over 5 days, bilateral congestion of the conjunctiva, erythema of the lips, buccal mucosa and the tongue, cervical lymphadenopathy, polymorphous exanthema[symptoma.com] There is sparse scattered lymphocytic infiltration centred around the basal layer /- vacuolar degeneration of the basal layer.[dermnetnz.org]

  • Pityriasis Circinata

    In the drug induced form there is no herald patch, individual lesions tend to be violet-red in colour, pruritus is more severe, and eosinophilia may be present.[doi.org] Pityriasis Rosea (PR) History:(i) Close contacts with similar eruptions: Mostly uncommon because most cases of PR are sporadic(ii) Medication intake: Could cause a similar exanthema[dailyrounds.org] Besides, histology shows epidermal atrophy and basal layer degeneration.[wjgnet.com]

  • Graft-versus-Host-Disease

    Acute cutaneous GvHD, consisting of symmetrical maculopapular exanthema with prominent acral erythema and accentuated lesions on the face and pinnae, was clinically suspected[ncbi.nlm.nih.gov] Skin biopsies were consistent with GVHD, showing vacuolar degeneration of the basal layer of the epithelium, epidermal infiltration by lymphocytes and necrotic eosinophilic[ncbi.nlm.nih.gov] But other patients with chronic GVHD never have eosinophilia, so the lack of eosinophilia does not influence the diagnosis of chronic GVHD.[oncologynurseadvisor.com]

  • Photosensitivity Disorder

    The syndrome typically includes skin rash and fever, often with hepatitis, arthralgias, lymphadenopathy, or haematological disorders (mainly eosinophilia and atypical lymphocytosis[pmj.bmj.com] Delayed type 4 allergic hypersensitivity reactions including aculopapular exanthema, erythematous rash, urticarial eruption, erythema multiforme, photodermatitis, eczema and[diki.pl] Microscopic evaluation revealed epidermal erosion and ulceration, with severe epidermal basal cell degeneration and necrosis, and superficial dermatitis (python and skink)[ncbi.nlm.nih.gov]

  • Lichen Sclerosus

    Diffuse fasciitis with eosinophilia associated with morphea and lichen sclerosus et atrophicus. Acta Derm Venereol (Stockh) 1985; 65: 80-3. Tafelkruyer J, Claessens FLE.[cirp.org] […] with hydropic degeneration of basal cell, flattening of rete ridges, pronounced edema, and homogenization of collagen in upper dermis with lymphocytic infiltrate in mid-dermis[ncbi.nlm.nih.gov] […] likely in similar diseases such as acrodermatitis chronica atrophicans. 157 Eosinophils are an unusual finding, 35, 158 but, Janovski and Ames 159 found significant tissue eosinophilia[cirp.org]

  • Human Herpesvirus 6

    Peripheral smear did not demonstrate eosinophilia but showed toxic granulation with atypical lymphocytes.[ncbi.nlm.nih.gov] Primary HHV-6 infection can cause acute encephalopathy without exanthema subitum.[ncbi.nlm.nih.gov] Results from a skin biopsy specimen demonstrated focal hydropic and vacuolar degeneration of epidermal basal cells, with marked exocytosis of atypical lymphoid cells into[jamanetwork.com]

  • Chronic Lichenoid Pityriasis

    Acquired digital fibrokeratoma Angiolymphoid hyperplasia with eosinophilia vs. Angiosarcoma Angiolymphoid hyperplasia with eosinophilia vs.[derm101.com] PMID: Exanthema* Humans; Parapsoriasis*. - A legjobb kezelés a bőr pikkelysömörében psoriasis guttata eczeem This work was supported in part by the Babcock Foundation psoriasis[vukosuzevolifog.xpg.uol.com.br] Epidermal changes include spongiosis and, characteristically, vacuolar degeneration of stratum basale. [22] Lymphocytic exocytosis into the epidermis is seen in EM as also[e-ijd.org]

  • Erythema Marginatum

    Another patient experienced exacerbations of EAC premenstrually as a type of autoimmune progesterone dermatitis. [27] Hypereosinophilic syndrome: A patient with 31% eosinophilia[emedicine.medscape.com] Such characteristics are similar to other exanthema which may arise due to any viral infection or disease.[patienthelp.org] Histopathology demonstrates epidermal atrophy, basal cell degeneration, and mononuclear cell infiltrate in the dermis.[ijpd.in]

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