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13 Possible Causes for Degeneration of Epidermal Basal Cells, Eosinophilia, Exanthema

  • Systemic Lupus Erythematosus

    A 42-year-old woman was admitted to our hospital with complaints of exanthema, arthralgia, shortness of breath, and hemoptysis.[] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[] In rare cases, pleural eosinophilia is associated with connective tissue disease.[]

  • Erythema Multiforme

    […] skin syndrome, Impetigo, Boil, Carbuncle ) · Strep ( Impetigo ) · Corynebacterium ( Erythrasma ) Viral skin disease Wart · Molluscum contagiosum · Erythema infectiosum · Exanthema[] Pathologic findings include liquefactive degeneration of the basal epidermal cells, necrotic keratinocytes, and exocytosis of lymphocytes.[] […] cytopenia, vasculitis, acute allergic interstitial nephritis, occupational contact dermatitis, photoallergic dermatitis, maculopapular eruption, erythroderma, Drug rash with eosinophilia[]

  • Vasculitis

    All serologic studies were normal except for increased levels of rheumatoid factor and eosinophilia.[] […] disease include fever lasting over 5 days, bilateral congestion of the conjunctiva, erythema of the lips, buccal mucosa and the tongue, cervical lymphadenopathy, polymorphous exanthema[] There is sparse scattered lymphocytic infiltration centred around the basal layer /- vacuolar degeneration of the basal layer.[]

  • Pityriasis Circinata

    In the drug induced form there is no herald patch, individual lesions tend to be violet-red in colour, pruritus is more severe, and eosinophilia may be present.[] Pityriasis Rosea (PR) History:(i) Close contacts with similar eruptions: Mostly uncommon because most cases of PR are sporadic(ii) Medication intake: Could cause a similar exanthema[] Besides, histology shows epidermal atrophy and basal layer degeneration.[]

  • Graft-versus-Host-Disease

    Acute cutaneous GvHD, consisting of symmetrical maculopapular exanthema with prominent acral erythema and accentuated lesions on the face and pinnae, was clinically suspected[] Skin biopsies were consistent with GVHD, showing vacuolar degeneration of the basal layer of the epithelium, epidermal infiltration by lymphocytes and necrotic eosinophilic[] But other patients with chronic GVHD never have eosinophilia, so the lack of eosinophilia does not influence the diagnosis of chronic GVHD.[]

  • Photosensitivity Disorder

    The syndrome typically includes skin rash and fever, often with hepatitis, arthralgias, lymphadenopathy, or haematological disorders (mainly eosinophilia and atypical lymphocytosis[] Delayed type 4 allergic hypersensitivity reactions including aculopapular exanthema, erythematous rash, urticarial eruption, erythema multiforme, photodermatitis, eczema and[] Microscopic evaluation revealed epidermal erosion and ulceration, with severe epidermal basal cell degeneration and necrosis, and superficial dermatitis (python and skink)[]

  • Lichen Sclerosus

    Diffuse fasciitis with eosinophilia associated with morphea and lichen sclerosus et atrophicus. Acta Derm Venereol (Stockh) 1985; 65: 80-3. Tafelkruyer J, Claessens FLE.[] […] with hydropic degeneration of basal cell, flattening of rete ridges, pronounced edema, and homogenization of collagen in upper dermis with lymphocytic infiltrate in mid-dermis[] […] likely in similar diseases such as acrodermatitis chronica atrophicans. 157 Eosinophils are an unusual finding, 35, 158 but, Janovski and Ames 159 found significant tissue eosinophilia[]

  • Human Herpesvirus 6

    Peripheral smear did not demonstrate eosinophilia but showed toxic granulation with atypical lymphocytes.[] Primary HHV-6 infection can cause acute encephalopathy without exanthema subitum.[] Results from a skin biopsy specimen demonstrated focal hydropic and vacuolar degeneration of epidermal basal cells, with marked exocytosis of atypical lymphoid cells into[]

  • Chronic Lichenoid Pityriasis

    Acquired digital fibrokeratoma Angiolymphoid hyperplasia with eosinophilia vs. Angiosarcoma Angiolymphoid hyperplasia with eosinophilia vs.[] PMID: Exanthema* Humans; Parapsoriasis*. - A legjobb kezelés a bőr pikkelysömörében psoriasis guttata eczeem This work was supported in part by the Babcock Foundation psoriasis[] Epidermal changes include spongiosis and, characteristically, vacuolar degeneration of stratum basale. [22] Lymphocytic exocytosis into the epidermis is seen in EM as also[]

  • Erythema Marginatum

    Another patient experienced exacerbations of EAC premenstrually as a type of autoimmune progesterone dermatitis. [27] Hypereosinophilic syndrome: A patient with 31% eosinophilia[] Such characteristics are similar to other exanthema which may arise due to any viral infection or disease.[] Histopathology demonstrates epidermal atrophy, basal cell degeneration, and mononuclear cell infiltrate in the dermis.[]

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