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57 Possible Causes for Degeneration of Epidermal Basal Cells, Fever

  • Vasculitis

    We must better appreciate the limitations of positron emission tomography in investigating a fever of unknown origin.[] There is sparse scattered lymphocytic infiltration centred around the basal layer /- vacuolar degeneration of the basal layer.[] Clinical manifestations including fever, polyarthralgia, and lung hemorrhage were on remission with a decrease of dysregulated NETs.[]

  • Systemic Lupus Erythematosus

    […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[] The patient showed a high spiking fever and myalgia. Laboratory data revealed pancytopenia and immunological abnormalities.[] We present a case of a previously healthy, 17 year old Asian female who presented to the ED with 14 days of fever and fatigue after administration of the meningococcal vaccine[]

  • Erythema Multiforme

    Pathologic findings include liquefactive degeneration of the basal epidermal cells, necrotic keratinocytes, and exocytosis of lymphocytes.[] EM major often starts with a fever and joint aches. Besides the skin sores and mouth sores, there may be sores in the eyes, genitals, lung airways, or gut.[] Histologic Features: Basal cell hydropic degeneration, which may be severe enough to result in the formation of subepidermal clefts or vesicles Apoptosis of keratinocytes,[]

  • Graft-versus-Host-Disease

    Skin biopsies were consistent with GVHD, showing vacuolar degeneration of the basal layer of the epithelium, epidermal infiltration by lymphocytes and necrotic eosinophilic[] The clinical findings mainly include high fever, cytopenia, splenomegaly, phagocytosis, and proliferation of histiocytes in lymphoreticular tissue.[] Two weeks after surgery she presented with complaints of fever, nausea, vomiting, upper abdominal discomfort, diarrhea, skin rash and petechie all over the body.[]

  • Lupus Erythematosus

    PATIENT CONCERNS: We report a 62-year-old Chinese man presented with recurrent erythematous facial plaques for 1 year and a low-grade fever for 1 week.[] […] of basal cells; 4) a predominantly lymphocytic infiltrate along the dermal-epidermal junction, around the fair follicles and eccrine ducts, in an interstitial pattern; 14[] Therefore, any unexpected fever should be reported and evaluated.[]

  • Rickettsialpox

    References Old-World Spotted Fevers: Global Status includes separate sections on African tick bite fever, Astrakhan fever, Israeli spotted fever, Rickettsia sibirica mongolotimonae[] There may be dermal and epidermal necrosis, perivascular inflammation, red blood cell extravasation and vacuolar degeneration in the basal cell layers.[] The recognition of the eschar preceded onset of fever by 0–4 days.[]

  • Erythema Annulare Centrifugum

    EAC is one of the figurate or gyrate erythemas, others being erythema marginatum (transiently seen in acute rheumatic fever), erythema migrans (rash of localized Lyme disease[] Histopathology demonstrates epidermal atrophy, basal cell degeneration, and mononuclear cell infiltrate in the dermis.[] There may be symptoms - such as night sweats, fever and chills - of underlying diseases (eg, Hodgkin's lymphoma or TB).[]

  • Pityriasis Circinata

    Sometimes, before the symptoms appear, people experience preliminary sensations including fever, malaise, sore throat, or headache.[] Besides, histology shows epidermal atrophy and basal layer degeneration.[] The rash may be accompanied by low-grade fever, headache, nausea and fatigue.[]

  • Erythema Marginatum

    However, the recent resurgence of rheumatic fever in middle-class families in the U. S.[] Histopathology demonstrates epidermal atrophy, basal cell degeneration, and mononuclear cell infiltrate in the dermis.[] The former group displayed inflammatory changes such as spongiosis and exocytosis, and focal liquefactive degeneration of the basal cell zone of the epidermis; while the latter[]

  • Chronic Lichenoid Pityriasis

    PLEVA may be associated with low-grade fever, malaise, headache, and arthralgia.[] Epidermal changes include spongiosis and, characteristically, vacuolar degeneration of stratum basale. [22] Lymphocytic exocytosis into the epidermis is seen in EM as also[] […] lichenoides et varioliformis acuta—PLEVA) to small, scaly, benign-appearing papules (pityriasis lichenoides chronica), to a rare febrile ulceronecrotic variant of PLEVA with high fever[]

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