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994 Possible Causes for Degeneration of Epidermal Basal Cells, Immunoglobulin G Increased, Mononeuritis Multiplex

  • Systemic Lupus Erythematosus

    multiplex, myelitis, peripheral neuropathy Blood: reduced numbers of red cells, white cells and platelets How is systemic lupus erythematosus diagnosed?[dermnetnz.org] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[medical-dictionary.thefreedictionary.com] Previously, we found increased immunoglobulin (Ig)G levels against varicella-zoster virus (VZV) in SLE patients compared to controls, while antibody levels against diphtheria[ncbi.nlm.nih.gov]

  • Rheumatoid Arthritis

    Neurological: peripheral nerve entrapment, Atlanto-axial subluxation, polyneuropathy, mononeuritis multiplex.[patient.info] multiplex) or progressive scleritis is typical of rheumatoid vasculitis.[hopkinsarthritis.org] The most common clinical manifestations of vasculitis are small digital infarcts along the nailbeds. ( see picture below ) The abrupt onset of an ischemic mononeuropathy (mononeuritis[hopkinsarthritis.org]

    Missing: Degeneration of Epidermal Basal Cells
  • Sjögren Syndrome

    multiplex [ 13 ].[patient.info] There is also evidence for increased intrathecal immunoglobulin G (IgG) synthesis.[epilepsy.com] multiplex, is a well established feature of the disease, occurring in approximately a quarter of patients. 2 However, involvement of the central nervous system (CNS) in patients[ard.bmj.com]

    Missing: Degeneration of Epidermal Basal Cells
  • Granulomatosis with Polyangiitis

    His hospital course was complicated by ischaemic stroke and a diagnosis of mononeuritis multiplex in his lower extremities.[ncbi.nlm.nih.gov] Nervous system involvement may be seen in approximately one-third of patients with peripheral neuropathies, the most common being mononeuritis multiplex; less frequently observed[aao.org] multiplex, cranial nerve abnormalities, central nervous system mass lesions, external ophthalmoplegia, hearing loss.[slideshare.net]

    Missing: Degeneration of Epidermal Basal Cells
  • Sarcoidosis

    Sarcoid neuropathy may present as sensorineural neuropathy, mononeuritis multiplex, or chronic inflammatory demyelinating neuropathy [ Vital et al. 2008 ].[doi.org]

    Missing: Degeneration of Epidermal Basal Cells
  • Rheumatoid Arteritis

    S ir , Peripheral nerve involvement is frequent in systemic vasculitis, typically either mononeuritis multiplex or sensorimotor peripheral polyneuropathy.[rheumatology.oxfordjournals.org] Nerves Mononeuritis multiplex/neuropathy. Kidneys Glomerulonephritis.[thecurbsiders.com] Mononeuritis multiplex predicts the need for immunosuppressive or immunomodulatory drugs for EGPA, PAN and MPA patients without poor-prognosis factors .[rheumatology.oxfordjournals.org]

    Missing: Degeneration of Epidermal Basal Cells
  • Diffuse Scleroderma

    Chest. 1983 Nov;84(5):546-50. Abstract The pulmonary function and chest roentgenograms were evaluated in 88 patients with the CREST syndrome variant of progressive systemic sclerosis (PSS or scleroderma). Seventy-two percent of the patients had abnormal pulmonary function. An isolated decrease in diffusing[…][ncbi.nlm.nih.gov]

    Missing: Degeneration of Epidermal Basal Cells
  • Cryoimmunoglobulinemic Syndrome

    multiplex in 19-44% of cases), kidney disease (primarily membranoproliferative glomerulonephritis (30%), joint pain (28%), and, less commonly, dry eye syndrome, Raynaud phenomenon[en.wikipedia.org] […] areas of necrosis occur in 69-89% of these mixed disease cases (see attached photograph); less common findings include painful peripheral neuropathy (often manifesting as mononeuritis[en.wikipedia.org]

    Missing: Degeneration of Epidermal Basal Cells
  • Systemic Amyloidosis

    In Figure 2 A, generally stable, low ( 1.5 g/dL) monoclonal immunoglobulin (M-Ig) levels are present for years before diagnosis, with a gradual increase resulting in a subsequent[doi.org] […] diagnostic M-Ig level of greater than 3 g/dL.[doi.org]

    Missing: Degeneration of Epidermal Basal Cells
  • Amyloidosis

    Int J Surg Pathol. 2018 May;26(3):271-275. doi: 10.1177/1066896917735893. Epub 2017 Oct 11. Abstract Amyloidosis caused by deposition of leukocyte cell-derived chemotaxin-2 amyloidosis (ALECT2) is the most recently described form of systemic amyloidosis and has quickly emerged as a common and possibly underdiagnosed[…][ncbi.nlm.nih.gov]

    Missing: Degeneration of Epidermal Basal Cells

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