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19 Possible Causes for Degeneration of Epidermal Basal Cells, Joint Swelling

  • Lupus Erythematosus

    […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[medical-dictionary.thefreedictionary.com] […] hip pain (osteonecrosis) Physical exam butterfly malar rash large joint swelling and synovitis hand and wrist manifestation are common (90%) swelling and synovitis of PIPs[orthobullets.com] Common symptoms include: severe fatigue joint pain joint swelling headaches a rash on the cheeks and nose, which is called a “butterfly rash” hair loss anemia blood-clotting[healthline.com]

  • Systemic Lupus Erythematosus

    […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[medical-dictionary.thefreedictionary.com] While denying a history of any rash, photosensitivity, oral ulcers, or seizures, his physical examination did reveal metacarpal phalangeal joint swelling along with noted[ncbi.nlm.nih.gov] […] hip pain (osteonecrosis) Physical exam butterfly malar rash large joint swelling and synovitis hand and wrist manifestation are common (90%) swelling and synovitis of PIPs[orthobullets.com]

  • Vasculitis

    There is sparse scattered lymphocytic infiltration centred around the basal layer /- vacuolar degeneration of the basal layer.[dermnetnz.org] Joints - pain and swelling in joints.[home.bt.com] swelling, warmth, painful range of motion Polyarteritis, Wegener's granulomatosis, Churg-Strauss vasculitis Skin lesions Livedo reticularis, necrotic lesions, ulcers, nodules[aafp.org]

  • Discoid Lupus Erythematosus

    A skin biopsy from her cheek revealed hyperkeratosis, focal epidermal atrophy, basal cell degeneration and dilated follicular orifices filled with compact keratin.[ncbi.nlm.nih.gov] They may sometime have symptoms of joint pain and joint swelling.[steadyhealth.com] […] membrane (best demonstrated by periodic acid-Schiff staining) and vacuolar degeneration of the basal cells along with perivascular and peri-appendageal inflammatory cell[doi.org]

  • Erythema Multiforme

    Pathologic findings include liquefactive degeneration of the basal epidermal cells, necrotic keratinocytes, and exocytosis of lymphocytes.[onlinelibrary.wiley.com] Sometimes there is arthralgia or even joint swelling.[ncbi.nlm.nih.gov] […] pain and swelling painful lesions if mucus is present Most erythema multiforme lesions are not painful, although some people may experience a burning sensation.[medicalnewstoday.com]

  • Rare Cutaneous Lichen Planus

    There is a T-cell infiltrate at the dermo-epidermal junction, with vacuolar or liquefactive degeneration of the basal cells of the epidermis.[news-medical.net] (inflammation) and painful joints antimalarial tablets – these help to treat and prevent malaria (a tropical disease spread by infected mosquitoes) Diagnosis Lichen planus[your.md] […] example: gold injections – these are disease-modifying anti-rheumatic drugs (DMARDs) which are sometimes injected into the muscles of people with arthritis to help reduce swelling[your.md]

  • Epidermolysis Bullosa Simplex

    epidermal cells.[ncbi.nlm.nih.gov] Traditionally, oral diacerein is used to treat arthritis to help manage pain and swelling of joints and has been shown to have effects in eczema, rash and itch because of[debra.org.uk] […] layer caused by degeneration of individual epidermal cells Dystrophic EB: pretibial lesion Electron microscopy description Electron microscopy images Images hosted on other[pathologyoutlines.com]

  • Chilblain Lupus Erythematosus

    In particular, skin histopathology of DLE shows classical features: vacuolar degeneration of basal cell layer; thickened basement membrane; orthokeratosis with follicular[ped-rheum.biomedcentral.com] […] with swelling, tenderness, or an effusion; rarely deforming (normal x-ray ) Serositis Pleuritis according to a history of pleuritic pain or a pleuritic rub during auscultation[amboss.com] The most common symptoms and signs of lupus include: - Fatigue - Joint pain and swelling - Sun sensitivity - Fingers or toes turn white and/or blue in the cold ( Raynaud's[rxlist.com]

  • Actinic Lichen Planus

    Histology classically demonstrates hyperkeratosis, epidermal thinning, vacuolar degeneration of the basal cell layer, lymphohistiocytic band-like infiltrate, variable Civatte[jcadonline.com] […] the medication pain, burning, numbness, or tingling of the treated skin muscle, joint, or back pain headache Some side effects can be serious.[medlineplus.gov] […] of the basal cell layer with pigment incontinence and keratinocyte apoptosis.[e-ijd.org]

  • Photosensitivity Disorder

    Microscopic evaluation revealed epidermal erosion and ulceration, with severe epidermal basal cell degeneration and necrosis, and superficial dermatitis (python and skink)[ncbi.nlm.nih.gov] Joint Pain and Swelling Up to 90 percent of people with lupus will have arthritis which is defined as inflammation or swelling of the joint lining.[lupusresearch.org] Nearly every SLE patient experiences swelling and joint pain and some develop additional arthritis – especially in the hands, wrists, fingers, and knees.[oncosec.com]

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