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14 Possible Causes for Degeneration of Epidermal Basal Cells, Polyarteritis Nodosa, Syphilis

  • Vasculitis

    A biopsy of subcutaneous nodes finds an anatomopathologic lesion of polyarteritis nodosa.[ncbi.nlm.nih.gov] […] vasculitic workup assists in determining the organ systems involved and may include urinalysis, C-reactive protein, urea nitrogen/creatinine, CBC, ANCA and ANA testing, syphilis[arupconsult.com] There is sparse scattered lymphocytic infiltration centred around the basal layer /- vacuolar degeneration of the basal layer.[dermnetnz.org]

  • Systemic Lupus Erythematosus

    Nodosa Classification Polymyalgia Rheumatica Classification Rheumatoid Arthritis Classification 2010 ACR/EULAR RA Classification Criteria Excerpt Tree Format Complete Article[rheumatology.org] […] with lupus tested positive for syphilis.[hopkinslupus.org] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[medical-dictionary.thefreedictionary.com]

  • Erythema Multiforme

    Secondary syphilis, the hematogenous spread of Treponema pallidum, usually occurs 4-10 weeks after initial exposure.[ncbi.nlm.nih.gov] Pathologic findings include liquefactive degeneration of the basal epidermal cells, necrotic keratinocytes, and exocytosis of lymphocytes.[onlinelibrary.wiley.com] Tertiary syphilis may presents as neuro-syphilis, cardiovascular syphilis or late benign syphilis.[ejcrim.com]

  • Lupus Erythematosus

    nodosa, • Scleroderma • Dermatomyositis 9.[slideshare.net] We subsequently reported structures analogous to iSALT in human secondary syphilis, suggesting that iSALT can also exist in humans.[ncbi.nlm.nih.gov] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[medical-dictionary.thefreedictionary.com]

  • Chronic Lichenoid Pityriasis

    Subcutaneous polyarteritis nodosa Pagetoid Bowen's disease vs. Extramammary Paget's disease Pale-cell acanthoma vs.[derm101.com] A few, such as secondary syphilis and viral-associated lesions, also can be excluded based on serologic tests.[dermaamin.com] Epidermal changes include spongiosis and, characteristically, vacuolar degeneration of stratum basale. [22] Lymphocytic exocytosis into the epidermis is seen in EM as also[e-ijd.org]

  • Tuberculid

    Histology of nodular tuberculid may be identical or very similar to polyarteritis nodosa.[6med-pdf.com] In our case, the condition mimicked secondary syphilis because of the involvement of palms and soles.[e-ijd.org] The earlobe biopsy showed epidermal hyperkeratosis and parakeratosis, liquefaction degeneration of the basal cells, and follicular keratotic plugging, and the blood vessels[cmj.yiigle.com]

  • Erythema Annulare Centrifugum

    nodosa 血栓性静脈炎 thrombophlebitis 5 海綿状態を呈する・血管周囲のみ炎症細胞浸潤がある炎症性疾患 多形慢性痒疹 prurigo chronica multiformis アトピー性皮膚炎 atopic dermatitis 6 乾癬様パターンをとる炎症性疾患 尋常性乾癬,遷延性病変(掻破による修飾) psoriasis[igaku-shoin.co.jp] Diagnosis: atypical secondary syphilis. Treatment: 0.8 million units of procaine penicillin i.m. per day 20 day.[academic.oup.com] Histopathology demonstrates epidermal atrophy, basal cell degeneration, and mononuclear cell infiltrate in the dermis.[ijpd.in]

  • Discoid Lupus Erythematosus

    nodosa, • Scleroderma • Dermatomyositis 9.[slideshare.net] Perioral dermatitis and rosacea Sarcoidosis Lichen planus Lichen planopilaris Dermatomyositis Syphilis (see secondary syphilis ) Porphyria (see erythropoietic protoporphyria[visualdx.com] A skin biopsy from her cheek revealed hyperkeratosis, focal epidermal atrophy, basal cell degeneration and dilated follicular orifices filled with compact keratin.[ncbi.nlm.nih.gov]

  • Familial Primary Localized Cutaneous Amyloidosis

    nodosa 血栓症 thrombosis 限局性結節性過形成 focal nodular hyperplasia 原発性肝癌 primary liver cancer 原発性硬化性胆管炎 primary sclerosing cholangitis 原発性胆汁性肝硬変 primary biliary cirrhosis 症候性原発性胆汁性肝硬変[jsge.or.jp] […] described by Fontanus (Fonteyn) in 1639, but Rokitansky is credited with identifying a lardaceous or waxy amyloid-like degradation in tissue in association with tuberculosis, syphilis[plasticsurgerykey.com] The major epidermal change observed was hyperkeratosis (90.90%), followed by acanthosis (72.71%), degeneration of basal cell layer (18.2%), elongated rete ridges (13.63%),[pigmentinternational.com]

  • Zinc-Responsive Necrolytic Acral Erythema

    Finger clubbing, aphthous ulcers of the mouth, 338 cutaneous polyarteritis nodosa, 339. and 340. psoriasis, 341 pyostomatitis vegetans, 342. 343. and 344. erythema multiforme[plasticsurgerykey.com] Striae 794 235 Subacute cutaneous lupus erythematosus 797 236 Subcorneal pustular dermatosis 802 237 Subcutaneous fat necrosis of the newborn 805 238 Sweet syndrome 807 239 Syphilis[books.google.com] However, the focal nature of epidermal dyskeratosis and pallor, along with basal cell vacuolar degeneration can be useful in distinguishing NAE from other clinical mimickers[dermatologyadvisor.com]

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