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14 Possible Causes for Degeneration of Epidermal Basal Cells, Rash of the Nose

  • Systemic Lupus Erythematosus

    Lupus is diagnosed when four of the following 11 criteria are present in a patient: Malar “butterfly” rash across the nose and cheeks Rash consisting of raised red patches[emedicinehealth.com] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[medical-dictionary.thefreedictionary.com] SLE also causes a characteristic butterfly shaped rash on the nose and cheeks called malar rash with exposure to the sun.[rheumatologyspecialistcare.com.au]

  • Discoid Lupus Erythematosus

    This rash is over the cheeks and across the bridge of the nose. There is no known cure for discoid lupus.[empowher.com] A skin biopsy from her cheek revealed hyperkeratosis, focal epidermal atrophy, basal cell degeneration and dilated follicular orifices filled with compact keratin.[ncbi.nlm.nih.gov] […] membrane (best demonstrated by periodic acid-Schiff staining) and vacuolar degeneration of the basal cells along with perivascular and peri-appendageal inflammatory cell[doi.org]

  • Lupus Erythematosus

    Lupus is diagnosed when four of the following 11 criteria are present in a patient: Malar “butterfly” rash across the nose and cheeks Rash consisting of raised red patches[emedicinehealth.com] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[medical-dictionary.thefreedictionary.com] rash" or "malar rash" Hair loss Mouth and nose ulcers Red sore dry eyes Body systems and organs sometimes affected by lupus include: Heart and lungs Inflammation of the outer[southerncross.co.nz]

  • Vasculitis

    Skin Joints Lungs Kidneys Gastrointestinal tract Blood Sinuses, nose, and ears Eyes Brain Nerve Skin A variety of rashes, the most classic of which is "palpable purpura" –[web.archive.org] There is sparse scattered lymphocytic infiltration centred around the basal layer /- vacuolar degeneration of the basal layer.[dermnetnz.org] It can lead to bulging eyes, shortness of breath, pain in the joints or muscles, rashes, and fatigue.[nyulangone.org]

  • Chilblain Lupus Erythematosus

    A: Across the nose and cheeks. Also called the "malar rash," the "butterfly rash" typically seen in lupus appears across the nose and cheeks in a butterfly-shape.[rxlist.com] In particular, skin histopathology of DLE shows classical features: vacuolar degeneration of basal cell layer; thickened basement membrane; orthokeratosis with follicular[ped-rheum.biomedcentral.com] See a GP if you often get: joint pain and stiffness extreme tiredness that won't go away no matter how much you rest skin rashes – often over the nose and cheeks As well as[nhs.uk]

  • Actinic Lichen Planus

    When someone has a rosacea-style rash on the nose, cheeks, chin, or forehead, it’s just a garden variety of eczema that happens to appear on t..[medicalmedium.com] Histology classically demonstrates hyperkeratosis, epidermal thinning, vacuolar degeneration of the basal cell layer, lymphohistiocytic band-like infiltrate, variable Civatte[jcadonline.com] […] of the basal cell layer with pigment incontinence and keratinocyte apoptosis.[e-ijd.org]

  • Photosensitivity Disorder

    A few things may alert or confirm that you that you may be photosensitive: Rashes may develop across the nose and cheeks after sun exposure; this is known as the butterfly[mollysfund.org] Microscopic evaluation revealed epidermal erosion and ulceration, with severe epidermal basal cell degeneration and necrosis, and superficial dermatitis (python and skink)[ncbi.nlm.nih.gov] This rash is typically seen on the nose and cheeks, called a malar rash, and is considered one of the hallmarks of lupus.[medicinenet.com]

  • Tuberculid

    .  These can be: nettle rash-like skin rash, Swells in the face and in the neck, Breathlessness, Circulatory failure. 9 a insect bit 10 common symptoms of allergy  Nose:[slideplayer.com] The earlobe biopsy showed epidermal hyperkeratosis and parakeratosis, liquefaction degeneration of the basal cells, and follicular keratotic plugging, and the blood vessels[cmj.yiigle.com] Focal lymphocytic infiltrate and focal vacuolar degeneration of the basal cell layer were seen at the dermal-epidermal junction.[cyberleninka.org]

  • Transient Bullous Dermolysis of the Newborn

    […] affecting his cheeks, nose and ears.[documents.tips] PAS-positive inclusions were present in the cytoplasm of a few basal cells. Examination by electron microscopy showed degeneration of the collagen and anchoring fibrils.[ncbi.nlm.nih.gov] In a freshly induced blister from transient bullous dermolysis of the newborn, we found in epidermal basal cells structures similar to anchoring fibrils and lamina densa,[ncbi.nlm.nih.gov]

  • Rickettsialpox

    Other symptoms may include: Discomfort in bright light ( photophobia ) Fever and chills Headache Muscle pain Rash that looks like chickenpox Sweating Runny nose Sore throat[medlineplus.gov] There may be dermal and epidermal necrosis, perivascular inflammation, red blood cell extravasation and vacuolar degeneration in the basal cell layers.[symptoma.com] Cough Enlarged lymph nodes Loss of appetite Nausea or vomiting The rash is not painful and usually clears within a week.[medlineplus.gov]

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