Create issue ticket

15 Possible Causes for Degeneration of Epidermal Basal Cells, Raynaud's Disease

  • Vasculitis

    Some of the most common types of vasculitis are: Raynaud’s disease (Raynaud's phenomenon) Buerger’s disease (thromboangitis obliterans) Takayasu’s arteritis The UC Davis Vascular[ucdmc.ucdavis.edu] There is sparse scattered lymphocytic infiltration centred around the basal layer /- vacuolar degeneration of the basal layer.[dermnetnz.org] Vasculitis may be associated with other systemic diseases, like arthritis, lupus erythematosus and other diseases of the immune system, as well as collagen vascular or connective[ucdmc.ucdavis.edu]

  • Systemic Lupus Erythematosus

    Some patients with SLE have Raynaud's phenomenon.[web.archive.org] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[medical-dictionary.thefreedictionary.com] phenomenon, pulmonary, hematological, gastrointestinal, ocular.[web.archive.org]

  • Lupus Erythematosus

    […] is most common cause of mortality hip osteonecrosis is common in patients taking glucocorticoids Raynaud's phenomenon Presentation Symptoms fever pain in multiple joints[orthobullets.com] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[medical-dictionary.thefreedictionary.com] The patient was a male aged 74 years old with gastric cancer characterized by the following symptoms: Raynaud phenomenon, polyarthralgia, and swollen parotid glands on both[ncbi.nlm.nih.gov]

  • Chilblain Lupus Erythematosus

    Low body mass index may predispose to pernio. 2 Dysproteinemias Macroglobulinemia Cryoglobulinemia, cryofibrinogenemia, cold agglutinins Antiphospholipid antibody syndrome Raynaud[dermaamin.com] In particular, skin histopathology of DLE shows classical features: vacuolar degeneration of basal cell layer; thickened basement membrane; orthokeratosis with follicular[ped-rheum.biomedcentral.com] Comments Case I was diagnosed as a case of CLE as she had Raynaud's phenomenon, chilblains, progressive disease with only partial improvement in summer, tapering of fingers[ijdvl.com]

  • Discoid Lupus Erythematosus

    The presence of Raynaud's phenomenon, swollen fingers, a high anti-nuclear antibody titer, and the results of a biopsy revealed limited-type systemic sclerosis (lSSc).[ncbi.nlm.nih.gov] A skin biopsy from her cheek revealed hyperkeratosis, focal epidermal atrophy, basal cell degeneration and dilated follicular orifices filled with compact keratin.[ncbi.nlm.nih.gov] Raynaud's phenomenon. Sun sensitivity. Joint pain . Itching and swelling on the skin. Pale or blue lips. Fast heart rate. Rapid breathing. Chest pain .[epainassist.com]

  • Zinc-Responsive Necrolytic Acral Erythema

    disease and phenomenon 722 216 Reactive arthritis 726 217 Regional pain and complex regional pain 730 218 Relapsing polychondritis 733 219 Rhinophyma 737 220 Rocky Mountain[books.google.com] However, the focal nature of epidermal dyskeratosis and pallor, along with basal cell vacuolar degeneration can be useful in distinguishing NAE from other clinical mimickers[dermatologyadvisor.com] 209 Pseudoxanthoma elasticum 695 210 Psoriasis 697 211 Psychogenic excoriation 708 212 Pyoderma gangrenosum 711 213 Pyogenic granuloma 716 214 Radiation dermatitis 719 215 Raynaud[books.google.com]

  • Rare Cutaneous Lichen Planus

    I learned an awful lot about Raynaud's phenomenon the day I typed "cold mouse hand" into Google and hit return.[theguardian.com] There is a T-cell infiltrate at the dermo-epidermal junction, with vacuolar or liquefactive degeneration of the basal cells of the epidermis.[news-medical.net] "Cold mouse hand" – a symptom that instantly returned once I started thinking about it again – did flag up Raynaud's phenomenon, but also paramyotonia congenita of Von Eulenburg[theguardian.com]

  • Bazex Syndrome

    […] scleroderma-like skin changes with Raynaud's phenomenon and osteolysis of distal phalanges.[ijmpo.org] […] and never of mesodermal origin, possible histopathological changes including the presence of necrotic foci, scattered vacuolar degeneration of basal cells, cytoplasmic eosinophilia[bmccancer.biomedcentral.com] Chronic arsenic toxicity causes diffuse or spotty rain drop pigmentation, hypopigmented macules, punctuate palmoplantar keratosis, Bowen's disease, etc., vinyl chloride causes[ijmpo.org]

  • Familial Primary Localized Cutaneous Amyloidosis

    The major epidermal change observed was hyperkeratosis (90.90%), followed by acanthosis (72.71%), degeneration of basal cell layer (18.2%), elongated rete ridges (13.63%),[pigmentinternational.com] phenomenon クワシオルコル症候群 Kwashiorkor syndrome 劇症肝炎 fulminant hepatitis 亜急性型 subacute type 急性型 acute type 劇症肝不全 fulminant hepatic failure 結核腫 tuberculoma 血性胆汁 hemobilia 血清病 serum[jsge.or.jp] phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia syndrome), primary biliary cirrhosis, rheumatoid arthritis, and systemic lupus erythematosus. [11] Other[emedicine.medscape.com]

  • Photosensitivity Disorder

    For doctors who manage those diseases, primarily lupus, scleroderma and Raynaud's phenomenon, the challenges of educating their patients about sun avoidance become greater[nytimes.com] Microscopic evaluation revealed epidermal erosion and ulceration, with severe epidermal basal cell degeneration and necrosis, and superficial dermatitis (python and skink)[ncbi.nlm.nih.gov] Ulcers, nodules, hemorrhagic blisters, or Raynaud’s disease may also be present, and additional organ systems may be involved. 5 DIV may occur 7 to 21 days after initial drug[uspharmacist.com]

Further symptoms

Similar symptoms