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14 Possible Causes for Degeneration of Epidermal Basal Cells, Raynaud's Disease, Syphilis

  • Vasculitis

    Some of the most common types of vasculitis are: Raynaud’s disease (Raynaud's phenomenon) Buerger’s disease (thromboangitis obliterans) Takayasu’s arteritis The UC Davis Vascular[ucdmc.ucdavis.edu] […] vasculitic workup assists in determining the organ systems involved and may include urinalysis, C-reactive protein, urea nitrogen/creatinine, CBC, ANCA and ANA testing, syphilis[arupconsult.com] There is sparse scattered lymphocytic infiltration centred around the basal layer /- vacuolar degeneration of the basal layer.[dermnetnz.org]

  • Systemic Lupus Erythematosus

    Some patients with SLE have Raynaud's phenomenon.[web.archive.org] […] with lupus tested positive for syphilis.[hopkinslupus.org] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[medical-dictionary.thefreedictionary.com]

  • Discoid Lupus Erythematosus

    The presence of Raynaud's phenomenon, swollen fingers, a high anti-nuclear antibody titer, and the results of a biopsy revealed limited-type systemic sclerosis (lSSc).[ncbi.nlm.nih.gov] Perioral dermatitis and rosacea Sarcoidosis Lichen planus Lichen planopilaris Dermatomyositis Syphilis (see secondary syphilis ) Porphyria (see erythropoietic protoporphyria[visualdx.com] A skin biopsy from her cheek revealed hyperkeratosis, focal epidermal atrophy, basal cell degeneration and dilated follicular orifices filled with compact keratin.[ncbi.nlm.nih.gov]

  • Lupus Erythematosus

    […] is most common cause of mortality hip osteonecrosis is common in patients taking glucocorticoids Raynaud's phenomenon Presentation Symptoms fever pain in multiple joints[orthobullets.com] We subsequently reported structures analogous to iSALT in human secondary syphilis, suggesting that iSALT can also exist in humans.[ncbi.nlm.nih.gov] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[medical-dictionary.thefreedictionary.com]

  • Chilblain Lupus Erythematosus

    Low body mass index may predispose to pernio. 2 Dysproteinemias Macroglobulinemia Cryoglobulinemia, cryofibrinogenemia, cold agglutinins Antiphospholipid antibody syndrome Raynaud[dermaamin.com] Benign appendageal tumors Plaques Psoriasis Lichen planus Nummular eczema Discoid lupus erythematosus Granuloma annulare Cutaneous T-cell lymphoma Kaposi's sarcoma Secondary syphilis[aafp.org] In particular, skin histopathology of DLE shows classical features: vacuolar degeneration of basal cell layer; thickened basement membrane; orthokeratosis with follicular[ped-rheum.biomedcentral.com]

  • Erythema Annulare Centrifugum

    Diagnosis: atypical secondary syphilis. Treatment: 0.8 million units of procaine penicillin i.m. per day 20 day.[academic.oup.com] Histopathology demonstrates epidermal atrophy, basal cell degeneration, and mononuclear cell infiltrate in the dermis.[ijpd.in] disease and phenomenon 722 216 Reactive arthritis 726 217 Regional pain and complex regional pain 730 218 Relapsing polychondritis 733 219 Rhinophyma 737 220 Rocky Mountain[books.google.de]

  • Zinc-Responsive Necrolytic Acral Erythema

    disease and phenomenon 722 216 Reactive arthritis 726 217 Regional pain and complex regional pain 730 218 Relapsing polychondritis 733 219 Rhinophyma 737 220 Rocky Mountain[books.google.com] However, the focal nature of epidermal dyskeratosis and pallor, along with basal cell vacuolar degeneration can be useful in distinguishing NAE from other clinical mimickers[dermatologyadvisor.com] Striae 794 235 Subacute cutaneous lupus erythematosus 797 236 Subcorneal pustular dermatosis 802 237 Subcutaneous fat necrosis of the newborn 805 238 Sweet syndrome 807 239 Syphilis[books.google.com]

  • Rare Cutaneous Lichen Planus

    Differential Diagnosis (Other conditions with similar appearance) Graft versus host disease Psoriasis, Guttate Lichen Nitidus Psoriasis, Plaque Lichen Simplex Chronicus Syphilis[ozarkderm.com] There is a T-cell infiltrate at the dermo-epidermal junction, with vacuolar or liquefactive degeneration of the basal cells of the epidermis.[news-medical.net] I learned an awful lot about Raynaud's phenomenon the day I typed "cold mouse hand" into Google and hit return.[theguardian.com]

  • Pseudopelade of Brocq

    Hapalonychia may also be attributed to myxedema, rheumatoid arthritis, anorexia, bulimia, Hansens disease, Raynaud phenomenon, oral retinoid therapy, or radiodermatitis 6.[wikivisually.com] Screen for syphilis with rapid plasma reagin (RPR) or venereal disease research laboratory (VDRL) serologic tests.[visualdx.com] Characteristic histological findingsincluded hyperkeratosis, epidermal atrophy, vacuolar degeneration of epidermal basal cells, follicular plugging, fibrous tract replacing[article.sapub.org]

  • Bazex Syndrome

    Gamborg-Nielsen palmar and plantar keratoderma. 8 Other non-hereditary diseases that may cause constricting bands with or without hyperkeratosis include: leprosy, tertiary syphilis[scielo.br] […] and never of mesodermal origin, possible histopathological changes including the presence of necrotic foci, scattered vacuolar degeneration of basal cells, cytoplasmic eosinophilia[bmccancer.biomedcentral.com] […] scleroderma-like skin changes with Raynaud's phenomenon and osteolysis of distal phalanges.[ijmpo.org]

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