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41 Possible Causes for Degeneration of Epidermal Basal Cells, Scarring Alopecia

  • Discoid Lupus Erythematosus

    […] hydropic degeneration of the basal cell layer, thickening of the basement membrane zone, telangiectasia, superficial and deep perivascular and periadnexal lymphocytic inflammatory[] […] with primary scarring alopecia.[] A skin biopsy from her cheek revealed hyperkeratosis, focal epidermal atrophy, basal cell degeneration and dilated follicular orifices filled with compact keratin.[]

  • Systemic Lupus Erythematosus

    […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[] alopecia, anti-dsDNA, and anti-Sm antibodies), (2) any other autoimmune connective tissue disease, and/or (3) antinuclear antibodies 1/320.[] It is erythematous, well demarcated and associated with scaling: Discoid lupus Other manifestations include livedo reticularis, diffuse or patchy non-scarring alopecia and[]

  • Pseudopelade of Brocq

    A clinicopathologic study of scarring alopecia due to lichen planus: comparison with scarring alopecia in discoid lupus erythematosus and pseudopelade.[] Characteristic histological findingsincluded hyperkeratosis, epidermal atrophy, vacuolar degeneration of epidermal basal cells, follicular plugging, fibrous tract replacing[] Pseudopelade of brocq- scarring alopecia Asked for Male, 25 Years I have this problem for last 12 years. Now it has turned to a very noticeable stage.[]

  • Actinic Lichen Planus

    Lichen pigmentosus with scarring alopecia and circulating antinuclear antibodies. Int J Dermatol 1990;29:227-8. [ PUBMED ] 21.[] Histology classically demonstrates hyperkeratosis, epidermal thinning, vacuolar degeneration of the basal cell layer, lymphohistiocytic band-like infiltrate, variable Civatte[] […] had scarring alopecia on scalp. patients with non-scarring alopecia were having alopecia areata, while one patient with scarring alopecia had pseudopelade of Brocq.[]

  • Rare Cutaneous Lichen Planus

    GLPLS is characterised by three distinctive features – scarring alopecia on the scalp, non-scarring alopecia in the armpit and groin and widespread scaly or keratotic lichenoid[] There is a T-cell infiltrate at the dermo-epidermal junction, with vacuolar or liquefactive degeneration of the basal cells of the epidermis.[] : close-up Inflammation and scarring Download Figure: 5 Frontal fibrosing alopecia Frontal alopecia with erythema and scaling.[]

  • Cutaneous Lupus Erythematosus

    Patients with chronic cutaneous lupus erythematosus must be treated aggressively to prevent permanent scarring and scarring alopecia, and it may be noted that the acute or[] […] of basal cells; 4) a predominantly lymphocytic infiltrate along the dermal-epidermal junction, around the fair follicles and eccrine ducts, in an interstitial pattern; 14[] BACKGROUND: Chronic cutaneous lupus erythematosus (CCLE) often affects the scalp resulting in scarring alopecia.[]

  • Bullous Lichen Planus

    The combination of follicular LP with scarring alopecia of scalp and non-scarring alopecia of axilla and pubis or other areas is known as Graham-Little syndrome. [7] LP can[] Degeneration of basal epidermal cells leads to exposure of the basement membrane antigens.[] The extensive vacuolation of basal cells led to the appearance of a dermo-epidermal cleft [Figure 3] .[]

  • Lupus Erythematosus

    Alopecia Diffuse thinning or hair fragility with visibly broken hairs, in the absence of other causes such as alopecia areata, drugs, iron deficiency, and androgenic alopecia[] […] of basal cells; 4) a predominantly lymphocytic infiltrate along the dermal-epidermal junction, around the fair follicles and eccrine ducts, in an interstitial pattern; 14[] Cicatricial (scarring) alopecia can be permanent.[]

  • Epidermolysis Bullosa Pruriginosa

    During her 50s, however, the patient developed new abnormalities with patchy scarring alopecia and perifollicular inflammation.[] […] layer caused by degeneration of individual epidermal cells Dystrophic EB: pretibial lesion Electron microscopy description Electron microscopy images Images hosted on other[] Folliculitis decalvans (FD) is a primary neutrophilic scarring alopecia of unclear etiology affecting the scalp of young adults [ 3 ].[]

  • Chilblain Lupus Erythematosus

    Diffuse non-scarring alopecia Alopecia often presents with generalized hair loss without signs of inflammation on the scalp.[] […] area and areas of cribriform scarring Other cutaneous features Wide follicular pits arise in the concha of the ears Eyebrows may be sparse and erythematous Scarring alopecia[] DLE… Tendency for scarring 56.  Prominent involvement of the adnexa o Follicular plugging o Scarring alopecia (Irreversible) 57.[]

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