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38 Possible Causes for Degeneration of Epidermal Basal Cells, Skin Plaque

  • Systemic Lupus Erythematosus

    Other skin problems that occur include large red, circular rashes (plaques), which may scar (called discoid lupus). Skin rashes are usually aggravated by sunlight.[my.clevelandclinic.org] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[medical-dictionary.thefreedictionary.com] Skin lesions begin as erythematous plaques and progress to atrophic scars. They cluster in light-exposed areas of the skin, such as the face, scalp, and ears.[merckmanuals.com]

  • Discoid Lupus Erythematosus

    It is characterized by the presence of discoid skin plaques showing varying degrees of edema, erythema, scaliness, follicular plugging, and skin atrophy.[sideeffects.embl.de] A skin biopsy from her cheek revealed hyperkeratosis, focal epidermal atrophy, basal cell degeneration and dilated follicular orifices filled with compact keratin.[ncbi.nlm.nih.gov] […] membrane (best demonstrated by periodic acid-Schiff staining) and vacuolar degeneration of the basal cells along with perivascular and peri-appendageal inflammatory cell[doi.org]

  • Cutaneous Amyloidosis

    Haemorrhagic blisters may form following skin trauma such as pinching The most characteristic skin lesions consist of waxy papules, nodules, or plaques.[pcds.org.uk] The major epidermal change observed was hyperkeratosis (90.90%), followed by acanthosis (72.71%), degeneration of basal cell layer (18.2%), elongated rete ridges (13.63%),[pigmentinternational.com] Lichen amyloidosis is the most common form of localised skin amyloid.[dermcoll.edu.au]

  • Lichen Simplex Chronicus

    Lichen Simplex Chronicus is characterized by lichenification of the affected skin, generating a thickened plaque with prominent skin markings.[pathwaymedicine.org] Moreover, basal cell degeneration is confined to tips of rete ridges and band like infiltration is conspicuously absent in HLP.[omicsonline.org] The skin lesions in both patients were symmetric hyperpigmented thickened plaques with prominent skin markings resembling lichen simplex chronicus.[ncbi.nlm.nih.gov]

  • Vasculitis

    Skin biopsy revealed leucocytoclastic vasculitis. Rash and symptoms resolved 10 days after initiating treatment with oral prednisone.[ncbi.nlm.nih.gov] There is sparse scattered lymphocytic infiltration centred around the basal layer /- vacuolar degeneration of the basal layer.[dermnetnz.org] […] of skin fibrosis Linear scleroderma: Bands of fibrosis; May be associated with facial hemiatrophy En coup de sabre Systemic sclerosis (Scleroderma): Subtypes Diffuse cutaneous[neuromuscular.wustl.edu]

  • Lichen Sclerosus

    From Wikidata Jump to navigation Jump to search A chronic inflammatory process affecting the skin.[wikidata.org] […] with hydropic degeneration of basal cell, flattening of rete ridges, pronounced edema, and homogenization of collagen in upper dermis with lymphocytic infiltrate in mid-dermis[ncbi.nlm.nih.gov] A chronic inflammatory process affecting the skin. It is characterized by the presence of white, indurated plaques, epidermal atrophy, and fibrosis of the upper dermis.[commons.wikimedia.org]

  • Lupus Erythematosus

    […] systemic signs are rare; characterized by the presence of discoid skin plaques showing varying degrees of edema, erythema, scaliness, follicular plugging, and skin atrophy[icd9data.com] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[medical-dictionary.thefreedictionary.com] Other skin problems that occur include large red, circular rashes (plaques), which may scar (called discoid lupus). Skin rashes are usually aggravated by sunlight.[my.clevelandclinic.org]

  • Bazex Syndrome

    […] and never of mesodermal origin, possible histopathological changes including the presence of necrotic foci, scattered vacuolar degeneration of basal cells, cytoplasmic eosinophilia[bmccancer.biomedcentral.com] A range of symmetrical dermatological manifestations, with a clear predilection to extremities, that encompasses erythematous squamous plaques, skin scaling and nail dystrophy[ncbi.nlm.nih.gov] […] on the skin of his palms, soles, ear lobes and apex of the nose.[ncbi.nlm.nih.gov]

  • Actinic Lichen Planus

    Actinic Lichen Planus THE KEY OF DIAGNOSIS ANNULAR LICHENOID PLAQUES LOCATED ON EXPOSED PARTS OF THE SKIN 3. ANNULAR LICHENOID PLAQUES 5.[slideshare.net] Histology classically demonstrates hyperkeratosis, epidermal thinning, vacuolar degeneration of the basal cell layer, lymphohistiocytic band-like infiltrate, variable Civatte[jcadonline.com] […] of the basal cell layer with pigment incontinence and keratinocyte apoptosis.[e-ijd.org]

  • Chilblain Lupus Erythematosus

    It is characterised by purple plaques/nodules and oedematous skin mainly around the acral regions of the body, which are most exposed to the cold.[ncbi.nlm.nih.gov] In particular, skin histopathology of DLE shows classical features: vacuolar degeneration of basal cell layer; thickened basement membrane; orthokeratosis with follicular[ped-rheum.biomedcentral.com] It is characterized by the presence of discoid skin plaques showing varying degrees of edema, erythema, scaliness, follicular plugging, and skin atrophy.[icdlist.com]

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