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1,683 Possible Causes for degradation, envelope, meiotic, nuclear

Did you mean: degradation, envelope, miotic, nuclear

  • Osteoporosis

    […] if in studies using individual randomisation allocation concealment was described as by central allocation (telephone, web‐based, or sequentially numbered, opaque, sealed envelopes[] Most of the interest is focused on cathepsins S and K, which display selective expression in cells of the immune system and cells capable to efficiently degrade extracellular[] Compared with GWLSs, GWASs can capitalize on all meiotic recombination events in a population, rather than only those in the families studied, and thus have higher statistical[] Author information 1 From the Department of Nuclear Medicine, Peking University People's Hospital, Beijing, China.[]

  • Autosomal Recessive Ataxia Type Beauce

    A mutation in the synaptic nuclear envelope protein 1 (SYNE1) gene that is located on chromosome 6p25 results in premature termination of the protein.[] This protein binds directly to cyclin E and probably targets cyclin E for ubiquitin-mediated degradation.[] […] recombination (S. cerevisiae) 11 homolog A MRE11 homolog A, double strand break repair nuclease MRE11 meiotic recombination 11 homolog A (S. cerevisiae) MRE11 MRE11A 600814[] envelope spectrin repeat protein 1 , synaptic nuclear envelope 1 , spectrin repeat containing, nuclear envelope 1 , chromosome 6 open reading frame 98 , nesprin-1-like Did[]

  • Emery-Dreifuss Muscular Dystrophy

    KEYWORDS: Emery–Dreifuss muscular dystrophy; Muscle biopsy; Nuclear envelope; Nuclear envelope transmembrane protein[] […] the transmembrane domain responsible for nuclear membrane targeting, so its incorrect localization and lack of function could be due to abnormal folding resulting in rapid degradation[] To more precisely define the functions of LB3T in nuclear assembly, we have expressed subdomains of LB3T and determined their effects on nuclear assembly in Xenopus extracts[] The lower molecular weight bands in (b) are emerin degradation products.[]

    Missing: meiotic
  • Influenza

    Morphology Virions consist of an envelope, a matrix protein, a nucleoprotein complex, a nucleocapsid, and a polymerase complex. Virus capsid is enveloped.[] Another substance, neuroaminidase, present in the virus is an enzyme that degrades the protective layer of mucus in the respiratory tract.[] To insure efficient transport across the nuclear membrane, these viruses use nuclear import and export signals exposed on the vRNPs.[] These IFN-stimulated genes inhibit viral replication by many different mechanisms, including binding to viral nucleocapsids, translation inhibition, RNA degradation, RNA editing[]

    Missing: meiotic
  • Triple A Syndrome

    Microscopic analysis of cells from a triple A patient revealed no morphological abnormalities of the nuclei, nuclear envelopes, or NPCs.[] In our cohort after the first decade of life, there does not appear to be any degradation of adrenal function over time.[] We then analyzed ALADIN’s localization throughout meiotic progression.[] Immunoblotting showed that fibroblasts from triple A patients (with known AAAS mutations) lack nuclear FTH1, suggesting that the nuclear translocation of FTH1 is defective[]

  • Progeria

    This phenotype is associated with ultrastructural perturbations to the nuclear envelope.[] We also evaluated the effect of associating rapamycin, which induces autophagic degradation of progerin and prelamin A.[] Our analysis indicated that MB treatment not only alleviated the mitochondrial defects but also rescued the hallmark nuclear abnormalities in HGPS cells.[] Treatment with rapamycin abolished nuclear blebbing, delayed the onset of cellular senescence, and enhanced the degradation of progerin in HGPS cells.[]

    Missing: meiotic
  • Polyploidy

    ) Offspring size increases throughout the day ( b ) until they fill the mother-cell cytoplasm ( c ). ( d ) Finally, “mature” offspring cells emerge from the mother-cell envelope[] Importantly, we have discovered that E6 mutants defective in p53 degradation also induce polyploidy, although with lower efficiency.[] The fertility of early generation polyploids increases rapidly, owing largely to selection against meiotic configurations that generate unbalanced gametes.[] In this study, we show how Ras activation causes aberrant nuclear localization of phosphorylated mitogen-activated protein (MAP)/extracellular signal-regulated kinase (ERK[]

  • Herpes Simplex Virus 1

    Herpes simplex virus 1 (HSV-1) envelope glycoprotein D (gD) plays an essential role in viral entry.[] (iii) The ICP0 C terminus is dispensable for PML I degradation.[] Nuclear egress of herpesviruses is accompanied by changes in the architecture of the nuclear membrane and nuclear lamina that are thought to facilitate capsid access to the[] IMPORTANCE HSV-1 glycoprotein B (gB) functions in the fusion of the viral envelope with cellular membranes during virus entry.[]

    Missing: meiotic
  • Oculopharyngeal Muscular Dystrophy

    Lentiviral production was performed using a DNA/CaCl 2 transfection mix of a combination of the lentiviral vector, packaging plasmids and an envelope expressing plasmid.[] Continuous myofiber remodeling most likely requires upregulation of genes involved in cell cycling, and in protein degradation and synthesis.[] As OPMD is usually transmitted as an autosomal-dominant meiotically stable trait, this case allows us to suggest that putative de novo OPMD mutations might occur more frequently[] Abstract Nuclear speckles are essential nuclear compartments involved in the assembly, delivery and recycling of pre-mRNA processing factors, and in the post-transcriptional[]

  • Urinary Tract Infection

    13/150 (8.7%) Unclear Yes Stothers 2002 Parallel 12 months Voided 10(8)/L Symptoms present (undefined) Yes, sealed envelopes 2/150 (1.3%) Participants, investigators Yes[] […] conserved process in which acidic double-membraned vacuoles sequester intracellular contents (such as damaged organelles and intracellular pathogens) and target them for degradation[] Author information 1 Department of Nuclear Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China. 2 Department of Nuclear Medicine[] Anne, Toulon, France. 3 Center for Microbial Ecology, Nocardiosis French Observatory, School of Pharmacy, University Claude Bernard Lyon 1, Lyon, France. 4 Department of Nuclear[]

    Missing: meiotic