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244 Possible Causes for degradation, phosphatidylethanolamine

  • Hypoalphalipoproteinemia

    Interestingly, apoA-I(FIN) was degraded in the plasma, and the extent of proteolysis correlated with the most significant reductions in murine apoA-I concentrations.[] Analysis of his EM lipids revealed normal cholesterol and phospholipid content but a marked increase in phosphatidylcholine with concomitant decreases in phosphatidylethanolamine[]

  • Vinyl Ether

    Abstract Fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (FDVE) is a fluorinated alkene formed by degradation of the volatile anesthetic sevoflurane in anesthesia[] Recently, we constructed a new smart nanoassembly (SNA) with multifunctional components that was composed of a condensed core of pDNA with protamine sulfate (PS) and a dioleoyl phosphatidylethanolamine[] Abstract The volatile anesthetic sevoflurane is degraded to fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether (FDVE), a potent rat nephrotoxin.[]

  • Newcastle Disease

    However, PP1 was degraded at late infection times, functionally counteracting the upregulation of GADD34.[] GFP-microtubule-associated protein 1 light chain 3 (GFP-LC3) puncta, formation of double-membrane vesicles and conversion of the nonlipidated form of LC3 (LC3-I) to the phosphatidylethanolamine-conjugated[] Furthermore, treatment with an ubiquitin E1 inhibitor PYR-41 demonstrated that phospho-STAT1 reduction was caused by degradation, but not de-phosphorylation.[]

  • Propantheline

    A novel strategy for the online monitoring of PB degradation kinetics catalysed by hydroxyl ions is presented.[] […] prodrugs ) Acetyl-coA Adafenoxate Choline ( lecithin ) Citicoline Cyprodenate Dimethylethanolamine Glycerophosphocholine Meclofenoxate (centrophenoxine) Phosphatidylcholine Phosphatidylethanolamine[] KEYWORDS: Activation energy; Calixarene; Degradation kinetics; Ion-selective electrode; On-line monitoring; Propantheline bromide[]

  • Osteosarcoma

    We further revealed that SETD2 upregulates H3K36me3 modification in GSK3B loci and promotes its transcription, which lead to β-catenin degradation.[] […] contained N -[1-(2,3-dioleoyloxy)propyl]- N , N , N -trimethylammonium methyl-sulfate (DOTAP), cholesterol, 1,2-dipalmitoyl- sn -glycero-3-phosphocholine (DPPC), and distearoyl-phosphatidylethanolamine-methyl-poly[] As examined by Edman degradation, the amino acid sequence of VACP1 is AQKWLKYWKADKVKGFGRKIKKIWFG. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assays[]

  • Spinal and Bulbar Muscular Atrophy

    This review illustrates the mechanisms at the basis of ARpolyQ degradation via the proteasomal and autophagic systems. Copyright 2010 Elsevier Inc. All rights reserved.[] Mass spectrometry analysis revealed an increase of phosphatidylethanolamines and phosphatidylserines in mitochondria isolated from SBMA muscles, as well as a 50% depletion[] Our results demonstrate that p62 provides two different therapeutic targets in SBMA pathogenesis: (1) autophagy-dependent degradation and (2) benevolent inclusion formation[]

  • Bile Salt

    In conclusion, our data suggest that ubiquitination facilitates clathrin-mediated endocytosis of BSEP and the degradation of internalized MRP2, leading to the degradation[] The expression of ABCB4, but not ABCB1, led to significant increases in the phosphatidylcholine (PC), phosphatidylethanolamine (PE), and sphingomyelin (SM) contents in nonraft[] Both NCTP and ASBT undergo post-translational regulations that involve phosphorylation/dephosphorylation, translocation to and retrieval from the plasma membrane and degradation[]

  • Ezetimibe

    Yet, the existence and importance of cholesterol degradation pathways in humans is a matter of debate.[] Mice lacking phosphatidylethanolamine N -methyltransferase (PEMT) are protected from high-fat diet (HFD)-induced obesity and insulin resistance.[] Degradation behaviour: HPLC studies on ezetimibe under different stress conditions suggested the following degradation behaviour.[]

  • Tangier Disease

    Thus, we have studied the potential of this abnormal lipoprotein to degrade PAF.[] To test this hypothesis we established an assay that measures the activity of plasma, cells, and cell culture media to transfer radiolabeled phosphatidylcholine (PC), phosphatidylethanolamine[] However, further degradation of neutral lipid or its transport away from Schwann cells appears to be retarded.[]

  • Vinblastine

    Preparative-scale recycling HPLC was used to purify the hydrolysis degradation products. All compounds were tested in eight different cancer cell lines and Vero cells.[] We showed that cobalamin-induced increase in cell phosphatidylcholine production was phosphatidylethanolamine-methyltransferase-dependent.[] Degraders chew up worn-out proteins, recyclers wrap up damaged organelles, and-most importantly-DNA repair crews restitch anything that resembles a broken chromosome.[]

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