Delayed Acquisition of Motor Skills: Causes & Reasons

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Possible Causes for Delayed Acquisition of Motor Skills

Déjerine-Sottas Disease

acquisition of motor skills Mild loss of hearing Limitation in eye movements Reduced muscle tone This condition can be diagnosed from the symptoms as well as your child’s [kidbones.net]

[…] in acquisition of motor skills in childhood occasionally, limitation of eye movements or other eye problems occasionally, mild hearing loss How does Dejerine-Sottas Disease [mda.org.au]

Occasionally there could be vision problems, hearing loss and delay in acquisition of motor skills in children. Treatment for this condition is symptomatic. [turmericforhealth.com]

Congenital Muscular Dystrophy with Integrin Alpha-7 Deficiency

Since delay of motor skill acquisition may be a presenting symptom of CMD, onset of manifestations before age two years may be a reasonable diagnostic criterion, although [invitae.com]

Since delay of motor skill acquisition may be a presenting symptom of CMD, onset of manifestations before age two years may be a reasonable diagnostic criterion. [ncbi.nlm.nih.gov]

delay and mild or moderate limb-girdle involvement during childhood. [invitae.com]

Barth Syndrome

[…] the acquisition of gross motor skills Exercise intolerance Muscle weakness Easily fatigued Chronic or recurrent diarrhea Feeding problems in infancy, "picky eating" in children [verywellhealth.com]

[…] of gross motor skills. [medium.com]

These symptoms can include: Heart conditions such as arrhythmias, heart failure, and cardiomyopathy Failure to thrive Delays in meeting developmental milestones Delays in [verywellhealth.com]

Mowat-Wilson Syndrome

The mental retardation, usually severe, was constant; the delay in the acquisition of motor skills was more variable (table 2). [jmg.bmjjournals.com]

Congenital Muscular Dystrophy due to LMNA Mutation

Since delay of motor skill acquisition may be a presenting symptom of CMD, onset of manifestations before age two years may be a reasonable diagnostic criterion, although [invitae.com]

delay and mild or moderate limb-girdle involvement during childhood. [invitae.com]

[…] variable within a spectrum and ranges from severe infantile onset hypotonia with feeding and respiratory complications and structural brain and eye abnormalities to moderate motor [invitae.com]

Pitt-Hopkins Syndrome

They also have severly imparied motor skills, including delayed acquisition of walking capability. [news-medical.net]

Rigid Spine Syndrome

Since delay of motor skill acquisition may be a presenting symptom of CMD, onset of manifestations before age two years may be a reasonable diagnostic criterion. [ncbi.nlm.nih.gov]

Poor or decreased motor abilities, delay or arrest of motor milestones, and joint or spinal deformities are often the presenting features of CMD. [ncbi.nlm.nih.gov]

Muscular Dystrophy-Dystroglycanopathy Type B6

Since delay of motor skill acquisition may be a presenting symptom of CMD, onset of manifestations before age two years may be a reasonable diagnostic criterion. [ncbi.nlm.nih.gov]

Poor or decreased motor abilities, delay or arrest of motor milestones, and joint or spinal deformities are often the presenting features of CMD. [ncbi.nlm.nih.gov]

Muscular Dystrophy-Dystroglycanopathy Type B5

Since delay of motor skill acquisition may be a presenting symptom of CMD, onset of manifestations before age two years may be a reasonable diagnostic criterion. [ncbi.nlm.nih.gov]

Poor or decreased motor abilities, delay or arrest of motor milestones, and joint or spinal deformities are often the presenting features of CMD. [ncbi.nlm.nih.gov]

Congenital Muscular Dystrophy Type Ullrich

Since delay of motor skill acquisition may be a presenting symptom of CMD, onset of manifestations before age two years may be a reasonable diagnostic criterion, although [invitae.com]

delay and mild or moderate limb-girdle involvement during childhood. [invitae.com]

Autosomal Recessive Cutis Laxa Type 2A

Muscle hypotonia can lead to secondary delay in motor skill acquisition. [nature.com]

In view of the frequent occurrence of microcephaly, the mild–moderate developmental delay is most likely central in origin. [nature.com]

Infantile-Onset Ascending Hereditary Spastic Paralysis

Abstract We studied 15 patients, from 10 families, who presented with severe spastic paralysis with an infantile onset and an ascending progression. Spastic paraplegia began during the first 2 years of life and extended to upper limbs within the next few years. During the first decade of life, the disease progressed[…] [ncbi.nlm.nih.gov]

MELAS Syndrome

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the[…] [grantome.com]

Limb-Girdle Muscular Dystrophy Type 2Q

Autosomal recessive limb-girdle muscular dystrophy-17 is characterized by early childhood onset of proximal muscle weakness and atrophy without skin involvement. One family has shown rapid progression of the disorder in adolescence (summary by Gundesli et al., 2010). For a discussion of genetic heterogeneity of[…] [ncbi.nlm.nih.gov]

Muscular Dystrophy-Dystroglycanopathy Type C2

Primary Outcome Measures : MRI scan for qualitative analysis of muscle involvement [ Time Frame: One MRI scan per subject (exam lasts approximately 60 min.) ] The MRI protocol include T1-weighted brain and whole body examination. Four cross-sectional slices at shoulder, lumbar back, thigh and calf are chosen for[…] [clinicaltrials.gov]

Muscular Dystrophy-Dystroglycanopathy Type C4

August 2017 ; 3 (4) Clinical/Scientific Notes Open Access Mateja Smogavec, Jana Zschüntzsch, Wolfram Kress, Julia Mohr, Peter Hellen, Barbara Zoll, Silke Pauli, Jens Schmidt First published July 10, 2017, DOI: https://doi.org/10.1212/NXG.0000000000000167 Limb-girdle muscular dystrophies (LGMDs) are a heterogeneous group[…] [ng.neurology.org]

Muscular Dystrophy-Dystroglycanopathy Type C1

Limb-girdle muscular dystrophy autosomal recessive type 2K (POMT1) DNA Test Leave Message Reporting Time: 5 Week Test Cost: 30000.00 /- Rs Sample Type: EDTA blood or DNA Limb-girdle muscular dystrophy autosomal recessive type 2K (POMT1) Test Description Limb-girdle muscular dystrophy autosomal recessive type[…] [dnalabsindia.com]

Hypomyelinating Leukodystrophy Type 5

Biancheri, R., Zara, F., Bruno, C., Gazzerro, E., Rossi, A., Knaap, M., & Minetti, C. (2015). Hypomyelination and Congenital Cataract. In R. A. Pagon, M. P. Adam, & H. H. Ardinger (Eds.), GeneReviews® [internet] Seattle (WA): University of Washington. Biancheri, R. ; Zara, F. ; Bruno, C. ; Gazzerro, E. ; Rossi, A. ; Knaap, M. ;[…] [research.vu.nl]

Spinocerebellar Ataxia Type 13

Spinocerebellar ataxia type 13 (SCA13) is a rare autosomal dominant disorder, which, like other types of SCA, is characterized by dysarthria, nystagmus, and ataxia of gait, stance and the limbs due to cerebellar dysfunction. Patients with SCA13 also tend to present with epilepsy, an inability to run, and increased[…] [en.wikipedia.org]

Aromatic L-Amino Acid Decarboxylase Deficiency

OBJECTIVE/CONTEXT: Long-fasting hypoglycemia in children may be induced by neurotransmitter disorders. A 5-year-old girl with a medical history of chronic diarrhea presented three episodes of severe hypoglycemia (20 mg/dL) between ages 3 and 5 years. She became pale and sweaty with hypothermia (33.5°C),[…] [ncbi.nlm.nih.gov]

Pompe Disease

Pompe disease is an inherited disorder caused by the buildup of a complex sugar called glycogen in the body's cells. The accumulation of glycogen in certain organs and tissues, especially muscles, impairs their ability to function normally. Researchers have described three types of Pompe disease, which differ in[…] [ghr.nlm.nih.gov]

Hereditary Areflexic Dystasia

C. Haubrich T. Krings J. Senderek S. Züchner J. Schröder J. Noth R. Töpper Diagnostic Neuroradiology Abstract. Hypertrophic radiculopathy is a rare feature of neuropathies. Single cases of enlarged nerve roots have been described in hereditary motor sensory neuropathies (HMSN) and chronic inflammatory[…] [doi.org]

Delta Aminolevulinate Dehydrase Deficiency

Gut. 1994 Aug;35(8):1112-5. Author information 1 University Department of Medicine and Therapeutics, Western Infirmary, Glasgow. Abstract Patients with acute hepatic porphyria are denied essential operations because of concern that general anaesthesia and surgery will precipitate a life threatening porphyric crisis.[…] [ncbi.nlm.nih.gov]

Moebius Syndrome

Möbius syndrome undoubtedly results from a variety of disorders affecting central or peripheral portions of appropriate cranial nerves or their target muscles. Pathological alterations observed in cranial nuclei are most often viewed as aplastic or dysplastic lesions. Two patients with Möbius syndrome with[…] [ncbi.nlm.nih.gov]

Scapuloperoneal Spinal Muscular Atrophy

Abstract Scapuloperoneal (SP) syndromes are heterogeneous neuromuscular disorders which are characterized by weakness in the distribution of shoulder girdle and peroneal muscles. SP syndromes can resemble facioscapulohumeral muscular dystrophy (FSH) due to scapular weakness or Charcot-Marie-Tooth disease[…] [ncbi.nlm.nih.gov]

Central Core Disease

Central core disease (CCD), also known as central core myopathy, is an autosomal dominant congenital myopathy (inborn muscle disorder). It was first described by Shy and Magee in 1956. It is characterized by the appearance of the myofibril under the microscope. The symptoms of CCD are variable, but usually involve[…] [en.wikipedia.org]

Congenital Myopathy with Excess of Thin Filaments

[…] de Winter, J. M., Buck, D., Hidalgo, C., Jasper, J. R., Malik, F. I., Clarke, N. F., ... Granzier, H. (2013). Troponin activator augments muscle force in nemaline myopathy patients with nebulin mutations. Journal of Medical Genetics, 50 (6), 383-392. https://doi.org/10.1136/jmedgenet-2012-101470 de Winter, J.M. ; Buck, D. ; Hidalgo,[…] [research.vu.nl]

Congenital Muscular Dystrophy Type 1A

Merosin-deficient congenital muscular dystrophy type 1A (MDC1A) is the most common form of congenital muscular dystrophy. MDC1A is caused by mutation of the laminin alpha-2 gene (LAMA2), localized to chromosome 6q22-23. The diagnosis of merosin-deficient CMD is based on the clinical findings of severe congenital[…] [ncbi.nlm.nih.gov]

Autosomal Recessive Centronuclear Myopathy

Centronuclear myopathies (CNM) describe a group of rare muscle diseases typically presenting an abnormal positioning of nuclei in muscle fibers. To date, three genes are known to be associated to a classical CNM phenotype. The X-linked neonatal form (XLCNM) is due to mutations in MTM1 and involves a severe and[…] [ncbi.nlm.nih.gov]

Achondroplasia

Achondroplasia is a common type of dwarfism. Achondroplasia is present at birth and is seen as disproportionately short-limbs, and specific facial features due to abnormal bone growth. Infants with achondroplasia suffer a high rate of apnea and sudden death in the neonatal period. The principle features of[…] [symptoma.com]