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1,978 Possible Causes for Delayed Bone Age, Hyperuricemia, Supraclavicular Fat Pads

  • Iatrogenic Cushing's Disease

    S257 - 8 ) 3 Cushing's syndrome caused by topical steroid therapy for psoriasis , Neth J Med , 2002 , vol. 60 (pg. 148 - 50 ) 4 Erythrodermic psoriasis associated with hyperuricemia[academic.oup.com] The indica ted treatment was topical with hydrocortisone acetate and delayed bone age (BA) (6 months BA for 1 year 3 months in chronological age).[scielo.conicyt.cl] Common: centripetal obesity with dorsocervical and supraclavicular fat pads, facial plethora and "moon face," fatigue, hyperglycemia, hypertension, mood lability, easy bruisability[hopkinsguides.com]

  • Cushing's Disease

    Individuals with Cushing syndrome can develop moon facies, facial plethora, supraclavicular fat pads, buffalo hump, truncal obesity, and purple striae, as shown in the image[emedicine.medscape.com] fat pads (buffalo hump) Usually, very slender distal extremities and fingers Muscle wasting and weakness are present.[merckmanuals.com] At baseline and at months 6 and 12, a reviewer at each site assessed patients for signs of hypercortisolism (facial rubor and supraclavicular and dorsal fat pads) by scoring[nejm.org]

  • Adrenal Cortex Hormone

    Cortisol and its synthetic analogs have been in widespread clinical use for the treatment of a variety of disorders for more than 50 years. Since their first clinical application, intensive research has expanded our understanding of the physiology, biochemistry, and pharmacology of steroids and has led to a large[…][ncbi.nlm.nih.gov]

  • Obesity

    Shadick NAKim RWeiss SLiang MHSparrow DHu H Effect of low level lead exposure on hyperuricemia and gout among middle aged and elderly men: the Normative Aging Study.[doi.org] Chuang SY, Lee SC, Hsieh YT, Pan WH (2011) Trends in hyperuricemia and gout prevalence: nutrition and Health Survey in Taiwan from 1993-1996 to 2005-2008.[doi.org] Campion EWGlynn RJDeLabry LO Asymptomatic hyperuricemia: risks and consequences in the Normative Aging Study. Am J Med 1987;82421- 426 PubMed Google Scholar Crossref 4.[doi.org]

    Missing: Delayed Bone Age
  • Morbid Obesity

    She presented high levels of blood urea, creatinine and aminotransferases, in addition to hyperkalemia and hyperuricemia.[ncbi.nlm.nih.gov] Weight loss programs may sometime lead to complications like cardiac arrhythmia, electrolyte derangements, hyperuricemia, cholelithiasis, and psychological conditions like[symptoma.com] The findings of morbid obesity, anasarca, self-injury, hyperuricemia and hypoxemia in Prader-Willi syndrome are emphasized.[ncbi.nlm.nih.gov]

    Missing: Delayed Bone Age
  • Sickle Cell Disease

    A 54-year-old Afro-Caribbean woman had a delayed diagnosis of homozygous sickle cell disease at 7 years of age by hemoglobin electrophoresis.[ncbi.nlm.nih.gov] The complications of sickle cell disease she experienced included bone pain, a chronic right leg ulcer, avascular necrosis of her left hip, and symptomatic cholelithiasis.[ncbi.nlm.nih.gov]

    Missing: Supraclavicular Fat Pads
  • Hypertension

    Epidemiological and experimental studies suggest a linkage between hyperuricemia and hypertension. Hyperuricemia affects 25-40 % of patients with untreated hypertension.[ncbi.nlm.nih.gov] fat pads, wide (1-cm) violaceous striae, hirsutism Overnight 1-mg dexamethasone suppression test 24-h urinary free cortisol excretion (preferably multiple); midnight salivary[dx.doi.org] ’s syndrome S5.4-12 Rapid weight gain, especially with central distribution; proximal muscle weakness; depression; hyperglycemia Central obesity, “moon” face, dorsal and supraclavicular[doi.org]

    Missing: Delayed Bone Age
  • Myelodysplasia

    Increased production and breakdown of blood cells can lead to hyperuricemia and hypermetabolism.[clevelandclinicmeded.com] Other features include short stature, hepatomegaly, recurrent infections, and bone abnormalities such as bone age delay, metaphyseal chondrodysplasia, and generalized osteopenia[preventiongenetics.com] Hypermetabolism caused by increased blood cell turnover can lead to hyperuricemia, gout, stomach ulcers, weight loss, and kidney stones.[clevelandclinicmeded.com]

    Missing: Supraclavicular Fat Pads
  • Thalassemia

    Splenectomy is a risk factor for developing hyperuricemia and nephrolithiasis in patients with thalassemia intermedia:a retrospective study. Blood cells Mol Dis.[emedicine.medscape.com] In those investigated, the most common findings were delayed bone age and coxa valga. Short stature was seen in two-thirds of cases.[ojrd.com] Occasionally, gout due to hyperuricemia, as well as kidney stones, are seen more frequently as patients with thalassemia major are living longer.[emedicine.medscape.com]

    Missing: Supraclavicular Fat Pads
  • Lipoid Nephrosis

    - uric acid strong association with hyperuricemia (eg, gout); often seen as a result of diseases with cell proliferation and turnover, such as leukemia & myeloproliferative[ome.umaryland.edu]

    Missing: Supraclavicular Fat Pads

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