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11 Possible Causes for Delayed Bone Age, Malocclusion, Wide Space Between the First and Second Toe

  • Dubowitz Syndrome

    Significant clinical correlation includes: smaU stature, microcephaly, abnormal ears, ptosis, hypertelorism, wide nasal bridge, dental malocclusion, eczema, and mental retardation[healio.com] Analysis of approximately 30 cases reveals prevalence of growth failure and delayed bone age, mild microcephaly, broad forehead with sparse frontal hair, telecanthus, blepharophimosis[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Seckel Syndrome

    Dental findings include hypodontia, enamel hypoplasia, crowding, and Class II malocclusion.[ncbi.nlm.nih.gov] bone age, hip dysplasia, and elbow dislocation (Faivre et al. 2002).[preventiongenetics.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Russell-Silver Syndrome

    Though orthodontic treatment may be performed for the malocclusion caused by growth disturbance and right - left asymmetry of viscerocranium, cleft palate is rarely complicated[ci.nii.ac.jp] However, in each child with RSS, a particular attention should be given to a decreased height velocity, a severely delayed bone age as well as a history of major perinatal[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Seckel Syndrome Type 2

    0010230 Cryptorchidism Undescended testes Undescended testis [ more ] 0000028 Dental crowding Crowded teeth Dental overcrowding Overcrowding of teeth [ more ] 0000678 Dental malocclusion[rarediseases.info.nih.gov] bone age, hip dysplasia, and elbow dislocation (Faivre et al. 2002).[preventiongenetics.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Cutis Laxa

    . , 1998), malocclusion, crossbite, dental crowding and diminished height of the alveolar bone (Lustmann et al. , 1993).[scielo.br] Radiological investigation of the hand wrist bone showed a markedly delayed bone age.[karger.com] . 1 An advanced bone age is often considered a prerequisite for the diagnosis. 2 3 The disorder is dominantly transmitted with most cases being isolated instances within kindreds[jmg.bmj.com]

  • Nicolaides-Baraitser Syndrome

    Hypogonadism with Mental Retardation and Skeletal Anomalies Male Pseudohermaphroditism/Mental Retardation Syndrome, Verloes Type Malignant Carcinoid Syndrome Mallory-Weiss Syndrome Malocclusion[rgd.mcw.edu] Bone age can be variable: 16 children with delayed bone age and two with advanced bone age have been reported.[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Baraitser Syndrome

    […] amenorrhea Hand polydactyly Ventricular hypertrophy Abnormal palate morphology Pancytopenia Low posterior hairline Bone marrow hypocellularity Amenorrhea Retinal dysplasia Dental malocclusion[mendelian.co] bone age, relative hypolipidemia, initial camptodactyly/joint contracture, progressive kyphoscoliosis, osteoporosis with loose joints, ventriculomegaly, and generalized organic[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Mild Dysmorphic Features

    .- ) cyclopia ( Q87.0 ) dentofacial anomalies [including malocclusion] ( M26.- ) malformation syndromes affecting facial appearance ( Q87.0 ) persistent thyroglossal duct[icd10data.com] , downslanting palpebral fissures, prominent nasal root, bulbous nasal tip, low-set ears, short fingers and toes with hypoplastic nails, and delayed bone age (Bonaglia et[unboundmedicine.com] , fourth, and fifth fingers; feet held in eversion, prominent heels; wide space between the first and second toes; proximally placed fifth toes; hypotonia; increased skin[ssmc-tl.com]

  • Macrocephaly-Developmental Delay Syndrome

    She also had joints with lax ligaments, a high arched palate, and dental malocclusion (upper front teeth extending over her lower front teeth).[chginc.org] Hand X-ray showed delayed bone age.[molecularcytogenetics.biomedcentral.com] space between first and second toes (sandal toes) clinodactyly of the fifth finger All of these are found in individuals without DS.[medicalhomeportal.org]

  • Short Stature - Wormian Bones - Dextrocardia Syndrome

    Management of the jaw deformity and malocclusion in adolescence (13–18 years). 45. Five levels of Tessier’s craniofacial framework. Level A, cranial vault.[slideshare.net] bone age, facial dysmorphisms, and expressive language delays, indicative to a specific set of signs, symptoms or other health indicators, associated with short stature with[wellnessadvocate.com] Wide spacing between first and second toes ( Matthews and Robin, 2011 ). 3. Skin. a. Short neck with excess nuchal skin. C. Associated findings. 1. Prematurity. 2.[nursekey.com]

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