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12 Possible Causes for Delayed Dentition, Hyperactivity, Wide Space Between the First and Second Toe

  • Down Syndrome

    Behavior suggestive of attention-deficit/hyperactivity disorder is often seen in childhood.[merckmanuals.com] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] In more rare cases, Down syndrome patients may be affected with hyperthyroidism, symptoms of which include breathing and sleeping difficulties, and hyperactivity.[symptoma.com]

  • Seckel Syndrome

    Most children with Seckel syndrome are "friendly and pleasant" but "often hyperkinetic (hyperactive) and easily distracted." This disease is genetic.[medicinenet.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] , and delayed eruption of the permanent dentition.[ncbi.nlm.nih.gov]

  • Atelosteogenesis Type 2

    Ethylmalonic Aciduria Excessive Daytime Sleepiness Exostoses, Multiple, Type II Extrapyramidal Movement Disorder Fabry Disease Faciogenital Dysplasia with Attention Deficit Hyperactivity[sequencing.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] dentition, and hypomyelination, see Pol III-related leukodystrophy ataxia, fatal X-linked, with deafness and loss of vision, see Arts syndrome ataxia-deafness-optic atrophy[mygenomics.com]

  • Kenny-Caffey Syndrome Type 1

    The endocrine glands that are hyperactive in the McCune–Albright syndrome have autonomous function. 4 5 6 7 8 9 One explanation for the manifestations of the disease is that[nejm.org] space between the first and second toes.[medcraveonline.com] Clinical features include cortical thickening and medullary stenosis of the tubular bones, delayed closure of fontanels, defective dentition, small eyes with hypermetropia[uniprot.org]

  • Craniofrontonasal Dysplasia

    […] or malfunction, or hormonalHP:0001852Sandal gapMP:0020157abnormal behavioral response to alcoholany anomaly in the behavioral response induced by alcohol, such as induced hyperactivity[pediascape.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] […] until the age of 5-8 years old, after permanent dentition. [8] A bifid nose tip is only treated at the age of 18 years, when the patient's skeleton has fully matured. [8][mjdrdypu.org]

  • Cutis Laxa

    Hyperactivity has also been reported in GO patients (Lisker et al. , 1979).[scielo.br] Early development was normal, except language and dentition delayed. There was no family history.[panafrican-med-journal.com] Other reported osteoarticular features are: a wide space between the first and second toes; talipes equinovarus; metatarsus adductus; genu recurvatum or genu valgum; flat[scielo.br]

  • Adactyly of Foot

    […] updated and includes new chapters on botanicals, genetics and nutritional aspects of birth defects, vegetarianism, obesity/eating disorders, autism, and attention deficit-hyperactivity[books.google.es] Synonyms:Anterior Polydactyly Replaces: Anterior Duplication of the Limb, Tibial Polydactyly Foot, Preaxial Polydactyly of Subjective: A widely spaced gap between the first[quizlet.com] Eczema Delayed eruption of teeth Abnormality of skin pigmentation Dry skin Malabsorption Telecanthus Recurrent infections Thrombocytopenia Neoplasm Vesicoureteral reflux[mendelian.co]

  • Baraitser Syndrome

    The child was found to be hyperactive, hyperkinetic, inattentive, most of the type happy and hyper sociable, being able to go away with complete strangers.[ijpd.in] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] […] acrodermatitis enteropathica, hyperpigmentation of the skin, very low insulin-like growth factor I levels with delayed bone age, relative hypolipidemia, initial camptodactyly[ncbi.nlm.nih.gov]

  • Nicolaides-Baraitser Syndrome

    The child was found to be hyperactive, hyperkinetic, inattentive, most of the type happy and hyper sociable, being able to go away with complete strangers.[ijpd.in] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Delayed tooth eruption is common, often requiring surgical extraction of primary dentition to allow secondary dentition to migrate into place.[ncbi.nlm.nih.gov]

  • Acrofacial Dysostosis Type Catania

    608905 Attention Deficit-Hyperactivity Disorder, Susceptibility to, 3 OMIM:608906 Attention Deficit-Hyperactivity Disorder, Susceptibility to, 4 OMIM:612311 Attention Deficit-Hyperactivity[informatics.jax.org] He had a wide space between the first and second toe of his feet and subungual fibroma on the second and third toe of the right foot and on the third toe of the left foot.[jmg.bmj.com] […] speech and language development Hyperactivity Gastroesophageal reflux Thickened skin Hoarse voice Abnormality of the dentition Polydactyly Anal atresia Short palm Postaxial[mendelian.co]

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