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13 Possible Causes for Delayed Dentition, Poor Feeding, Wide Space Between the First and Second Toe

  • Down Syndrome

    Marked hypotonia or other feeding difficulties should prompt a radiographic swallowing assessment.[patient.info] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] Tachypnea, feeding difficulties, and poor weight gain may indicate heart failure.[dx.doi.org]

  • Atelosteogenesis Type 2

    Surgical intervention is indicated for articulation problems and also for feeding difficulties (poor suckling), dental problems (spreading of the lower incisor teeth), or[oralmaxillo-facialsurgery.blogspot.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] dentition, and hypomyelination, see Pol III-related leukodystrophy ataxia, fatal X-linked, with deafness and loss of vision, see Arts syndrome ataxia-deafness-optic atrophy[mygenomics.com]

  • Kenny-Caffey Syndrome Type 1

    difficulties Lethargy Hypoglycemia Hypotonia Liver problems After infancy include: Hypotonia Muscle pain Breakdown of muscle tissue Peripheral neuropathy Infants with mitochondrial[wikidoc.org] space between the first and second toes.[medcraveonline.com] Clinical features include cortical thickening and medullary stenosis of the tubular bones, delayed closure of fontanels, defective dentition, small eyes with hypermetropia[uniprot.org]

  • Craniofrontonasal Dysplasia

    difficulty.[mjdrdypu.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] […] until the age of 5-8 years old, after permanent dentition. [8] A bifid nose tip is only treated at the age of 18 years, when the patient's skeleton has fully matured. [8][mjdrdypu.org]

  • Seckel Syndrome

    A 1-day-old female newborn was admitted with dysmorphic features and feeding difficulties. The parents were consanguineous.[pediatricneurologybriefs.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] , and delayed eruption of the permanent dentition.[ncbi.nlm.nih.gov]

  • Cutis Laxa

    Initial poor feeding improved spontaneously after a week and the baby was discharged.[jmg.bmj.com] Other reported osteoarticular features are: a wide space between the first and second toes; talipes equinovarus; metatarsus adductus; genu recurvatum or genu valgum; flat[scielo.br] Early development was normal, except language and dentition delayed. There was no family history.[panafrican-med-journal.com]

  • Adactyly of Foot

    difficulties Sensorineural hearing impairment Hypogonadism Transverse vaginal septum Nail pits Dacryocystitis Sparse pubic hair Blepharitis Xerostomia Sparse axillary hair[mendelian.co] Synonyms:Anterior Polydactyly Replaces: Anterior Duplication of the Limb, Tibial Polydactyly Foot, Preaxial Polydactyly of Subjective: A widely spaced gap between the first[quizlet.com] Eczema Delayed eruption of teeth Abnormality of skin pigmentation Dry skin Malabsorption Telecanthus Recurrent infections Thrombocytopenia Neoplasm Vesicoureteral reflux[mendelian.co]

  • Nicolaides-Baraitser Syndrome

    difficulties, muscular hypotonia, sandal gaps neonatal mild feeding difficulties, sandal gaps fetal finger pads, super-numerary interphalangeal creases, short lingual frenum[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Delayed tooth eruption is common, often requiring surgical extraction of primary dentition to allow secondary dentition to migrate into place.[ncbi.nlm.nih.gov]

  • Acrofacial Dysostosis Type Catania

    difficulties in infancy Intrauterine growth retardation Low-set, posteriorly rotated ears Preauricular pit Occasionally present symptoms in 5-29% of the cases: Clinodactyly[dovemed.com] He had a wide space between the first and second toe of his feet and subungual fibroma on the second and third toe of the right foot and on the third toe of the left foot.[jmg.bmj.com] […] speech and language development Hyperactivity Gastroesophageal reflux Thickened skin Hoarse voice Abnormality of the dentition Polydactyly Anal atresia Short palm Postaxial[mendelian.co]

  • Baraitser Syndrome

    difficulties in infancy Abnormal heart morphology Patent ductus arteriosus Inguinal hernia Atrial septal defect Low-set ears Low-set, posteriorly rotated ears Hydronephrosis[mendelian.co] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] […] acrodermatitis enteropathica, hyperpigmentation of the skin, very low insulin-like growth factor I levels with delayed bone age, relative hypolipidemia, initial camptodactyly[ncbi.nlm.nih.gov]

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