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13 Possible Causes for Delayed Dentition, Wide Space Between the First and Second Toe

  • Down Syndrome

    A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] spacing, often with a deep plantar groove between the first and second toes.[doi.org] […] fissures, Brushfield spots, small mouth, small ears, excessive skin at the nape of the neck, single transverse palmar crease, and short fifth finger with clinodactyly and wide[doi.org]

  • Atelosteogenesis Type 2

    dentition, and hypomyelination, see Pol III-related leukodystrophy ataxia, fatal X-linked, with deafness and loss of vision, see Arts syndrome ataxia-deafness-optic atrophy[mygenomics.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] […] dehydrogenase deficiency ataxia with lactic acidosis, type II, see pyruvate carboxylase deficiency ataxia with oculomotor apraxia ataxia with vitamin E deficiency ataxia, delayed[mygenomics.com]

  • Kenny-Caffey Syndrome Type 1

    space between the first and second toes.[medcraveonline.com] Clinical features include cortical thickening and medullary stenosis of the tubular bones, delayed closure of fontanels, defective dentition, small eyes with hypermetropia[uniprot.org] […] deep-set eyes, upward-slanting palpebral fissures, beaked nose, thin lips with a long philtrum, micrognathia, small hands and feet, Single transverse palmar crease, and wide[medcraveonline.com]

  • Craniofrontonasal Dysplasia

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] […] until the age of 5-8 years old, after permanent dentition. [8] A bifid nose tip is only treated at the age of 18 years, when the patient's skeleton has fully matured. [8][mjdrdypu.org] Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first and second toes Widened gap 1st-2nd toes Widened gap first and[rarediseases.info.nih.gov]

  • Cutis Laxa

    Other reported osteoarticular features are: a wide space between the first and second toes; talipes equinovarus; metatarsus adductus; genu recurvatum or genu valgum; flat[scielo.br] Early development was normal, except language and dentition delayed. There was no family history.[panafrican-med-journal.com] Abnormal positioning of fingers and toes, including adducted thumbs, is frequent (Reisner et al. , 1971; Philip, 1978) and was observed in both of our patients.[scielo.br]

  • Seckel Syndrome

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] , and delayed eruption of the permanent dentition.[ncbi.nlm.nih.gov] Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first and second toes Widened gap 1st-2nd toes Widened gap first and[rarediseases.info.nih.gov]

  • Adactyly of Foot

    Synonyms:Anterior Polydactyly Replaces: Anterior Duplication of the Limb, Tibial Polydactyly Foot, Preaxial Polydactyly of Subjective: A widely spaced gap between the first[quizlet.com] Eczema Delayed eruption of teeth Abnormality of skin pigmentation Dry skin Malabsorption Telecanthus Recurrent infections Thrombocytopenia Neoplasm Vesicoureteral reflux[mendelian.co] toe (the great toe) and the second toe Comments:The term is a subjective one but should be used when the gap between the toes is as wide as the second toe is broad.[quizlet.com]

  • Nicolaides-Baraitser Syndrome

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Delayed tooth eruption is common, often requiring surgical extraction of primary dentition to allow secondary dentition to migrate into place.[ncbi.nlm.nih.gov] Dental eruption is delayed inonethird of cases, which may involveprimary dentition, but more frequentlyinvolved secondary dentition.[docslide.com.br]

  • Baraitser Syndrome

    […] acrodermatitis enteropathica, hyperpigmentation of the skin, very low insulin-like growth factor I levels with delayed bone age, relative hypolipidemia, initial camptodactyly[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Delayed tooth eruption is common, often requiring surgical extraction of primary dentition to allow secondary dentition to migrate into place.[ncbi.nlm.nih.gov]

  • Acrofacial Dysostosis Type Catania

    He had a wide space between the first and second toe of his feet and subungual fibroma on the second and third toe of the right foot and on the third toe of the left foot.[jmg.bmj.com] […] speech and language development Hyperactivity Gastroesophageal reflux Thickened skin Hoarse voice Abnormality of the dentition Polydactyly Anal atresia Short palm Postaxial[mendelian.co] There was cutaneous syndactyly of the second and third fingers of the left hand.[jmg.bmj.com]

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