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2,675 Possible Causes for Delayed Development of Motor Skills, Multiple Congenital Anomalies, Wide Space Between the First and Second Toe

  • Down Syndrome

    Poor oral motor control may impact the development of language skills.[dseinternational.org] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] spacing, often with a deep plantar groove between the first and second toes.[dx.doi.org]

  • Russell-Silver Syndrome

    motor skills and early puberty 55.[doi.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] congenital anomalies/dysmorphic syndrome-variable intellectual disability syndrome, malformation syndrome with short stature, polymalformative genetic syndrome with increased[commons.wikimedia.org]

  • Mucopolysaccharidosis

    During the first stage, early mental and motor skill development may be somewhat delayed.[en.wikipedia.org]

    Missing: Wide Space Between the First and Second Toe
  • Prader-Willi Syndrome

    In addition, children with PWS might experience speech and sleep disorders, as well as scoliosis and delayed motor skill development.[penfieldbuildingblocks.org] Birth defects are also called congenital anomalies.[en.wikipedia.org] Motor and language development are significantly delayed, and there are difficulties with gross motor skills, coordination and balance, voice problems (primarily hypernasality[web.archive.org]

    Missing: Wide Space Between the First and Second Toe
  • Mowat-Wilson Syndrome

    development and motor skills.[medicinenet.com] Recently mutations in the gene ZFHX1B (SIP1) were shown in patients with "syndromic Hirschsprung disease" with mental retardation (MR) and multiple congenital anomalies (MCA[ncbi.nlm.nih.gov] We report a two-year-old boy with multiple congenital anomalies. He had peripupillary atrophy and gingival hypertrophy different from the literature.[ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Dubowitz Syndrome

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] This group will include 50% with chromosomal disorders congenital anomaly syndromes, especially recognizable by performing a karyotype, the details about their features and[books.google.com] The Dubowitz syndrome is a rare autosomal recessive multiple congenital anomaly/mental retardation syndrome.[ncbi.nlm.nih.gov]

    Missing: Delayed Development of Motor Skills
  • Trisomy X Syndrome

    […] speech, deficient language skills, and delayed development of motor skills.[susans.org] development of motor skills such as language and speech Learning difficulties like dyslexia Proportionately smaller head size or microcephaly Introvert Enamel Hypoplasia[syndromespedia.com] […] speech and language development, and difficulty reading Delayed motor skills, such as sitting and walking Problems processing sound Behavioral and emotional problems, including[everydayhealth.com]

    Missing: Wide Space Between the First and Second Toe
  • Trisomy 10p

    Signs and symptoms that can be present in a person with a 10p duplication may include delay of development, motor skills, or growth; short stature ; low muscle tone ( hypotonia[rarediseases.info.nih.gov] spaced, inverted nipples, mild pectus excavatum; and a sandal gap between the first and second toes.[jmg.bmj.com] congenital anomalies.[ncbi.nlm.nih.gov]

  • Patau Syndrome

    There can also be delayed motor skills - sitting, crawling and walking in infancy, and delayed cognitive skills such as speech and language acquisition and in short-term memory[mothers35plus.co.uk] Trisomy 13 or Patau syndrome (PS) is a chromosomal disorder characterized by a well known presentation of multiple congenital anomalies.[ncbi.nlm.nih.gov] congenital anomalies.[genome.jp]

    Missing: Wide Space Between the First and Second Toe
  • Atelosteogenesis Type 2

    As a result of their orthopedic abnormalities, they also have delayed development of motor skills such as standing and walking.[ghr.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Kabuki syndrome (KS) is a multiple congenital anomaly syndrome characterized by typical facial features, skeletal anomalies, mild to moderate intellectual disability and postnatal[blueprintgenetics.com]