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1,586 Possible Causes for Delayed Development of Motor Skills, Short Stature in Children, Wide Space Between the First and Second Toe

  • Down Syndrome

    Poor oral motor control may impact the development of language skills.[dseinternational.org] Short stature as the major manifestation of celiac disease in older children. Clin Pediatr 1986; 25:13–6. 12. Rossi TM, Kumar V, Lerner A, et al.[journals.lww.com] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org]

  • Russell-Silver Syndrome

    motor skills and early puberty 55.[doi.org] Russell-Silver syndrome (RSS) is characterized by slow growth both in utero and after birth, short stature, and specific facial features.[gemssforschools.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Mucopolysaccharidosis

    During the first stage, early mental and motor skill development may be somewhat delayed.[en.wikipedia.org] Only 2 pathogenic variants have been reported for the HYAL1 gene: Missense mutation c.802G A; p.E268K reported in association with short stature phenotype 35 Small deletion[centogene.com] Affected children may also have an abnormally large head (macrocephaly), a short neck and broad chest, delayed tooth eruption, progressive hearing loss, and enlargement of[rarediseases.org]

    Missing: Wide Space Between the First and Second Toe
  • SHORT Syndrome

    They can take time to develop after the child acquires gross motor skills.[medicalnewstoday.com] Short Stature in Children Symptoms Short parents tend to have short children.[emedicinehealth.com] Gross motor skills like crawling and walking can be slow to mature and fine motor skills may take time to develop.[medicinenet.com]

    Missing: Wide Space Between the First and Second Toe
  • Niemann-Pick Disease

    […] of fine motor skills.[clapway.com] stature and eye abnormalities Type C Symptoms of the type C form of Niemann-Pick disease usually begin to appear in children around 5 years old.[healthline.com] NPC has been initially diagnosed as a learning disability, mild retardation, “clumsiness,” and delayed development of fine motor skills.[nnpdf.org]

    Missing: Wide Space Between the First and Second Toe
  • Gaucher Disease

    Children with massive splenomegaly may be short in stature because of the energy expenditure required by the enlarged organ.[emedicine.medscape.com] [ncbi.nlm.nih.gov] Children with massive splenomegaly may be short in stature because of the energy expenditure required by the enlarged organ.[symptoma.com]

    Missing: Wide Space Between the First and Second Toe
  • Secondary Malnutrition

    In addition, infants and young children who have malnutrition frequently demonstrate developmental delay in delayed achievement of motor skills, delayed mental development[emedicine.medscape.com] Health and physical consequences of prolonged states of malnourishment among children are: delay in their physical growth and motor development; lower intellectual quotient[bmcpublichealth.biomedcentral.com] (IQ), greater behavioural problems and deficient social skills; susceptibility to contracting diseases .[bmcpublichealth.biomedcentral.com]

    Missing: Wide Space Between the First and Second Toe
  • Prader-Willi Syndrome

    In addition, children with PWS might experience speech and sleep disorders, as well as scoliosis and delayed motor skill development.[penfieldbuildingblocks.org] Short stature and short hands and feet are typical of PWS. Growth retardation is common and such children fail to thrive.[symptoma.com] Motor and language development are significantly delayed, and there are difficulties with gross motor skills, coordination and balance, voice problems (primarily hypernasality[web.archive.org]

    Missing: Wide Space Between the First and Second Toe
  • Fucosidosis

    People with this condition often have delayed development of motor skills such as walking; the skills they do acquire deteriorate over time.[ghr.nlm.nih.gov] People with this condition often have delayed development of motor skills such as walking, and the skills they do acquire often deteriorate over time.[diseaseinfosearch.org] Affected individuals have intellectual disability that worsens with age, and many develop dementia later in life.[ghr.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Septo-Optic Dysplasia

    Compared to other children referred for evaluation of short stature, children with SOD were younger (mean age 3.7 /- 3.6 vs 8.6 /- 4.9 years), had less severe short stature[ncbi.nlm.nih.gov] We report 5 children with SOD, originally referred to be evaluated due to short stature, who also presented bilateral optic nerve hypoplasia, nystagmus and development delay[ncbi.nlm.nih.gov] stature.[scielo.br]

    Missing: Wide Space Between the First and Second Toe