Delayed Gastric Emptying: Causes & Reasons

Possible Causes for Delayed Gastric Emptying

OBJECTIVES: Patients with autoimmune gastritis may have symptoms suggestive of delayed gastric emptying. [ncbi.nlm.nih.gov]

[…] affect delayed gastric emptying. [ncbi.nlm.nih.gov]

Gastroparesis cardinal symptom index has a high sensitivity and specificity in predicting both autonomic nerve function and delay in gastric emptying. [ncbi.nlm.nih.gov]

Diabetic Autonomic Neuropathy

Abstract Delayed gastric emptying secondary to diabetic autonomic neuropathy (DAN) is a recognized risk factor for aspiration pneumonitis. [ncbi.nlm.nih.gov]

Gastroenterological investigations showed delayed gastric emptying. RR ratio (respiration and standing) was abnormal. Resolution occurred after two years. [ncbi.nlm.nih.gov]

GENERAL ARTICLE: PDF Only Abstract Delayed gastric emptying secondary to diabetic autonomic neuropathy (DAN) is a recognized risk factor for aspiration pneumonitis. [pdfs.journals.lww.com]

Gastroesophageal Reflux Disease

An association between gastroesophageal reflux and delayed gastric emptying is recognized. This is more common in premature infants. [emedicine.medscape.com]

Delayed gastric emptying (DGE) is a major postoperative complication after pylorus-preserving pancreatoduodenectomy (PpPD) and sometimes causes reflux esophagitis. [ncbi.nlm.nih.gov]

gastric emptying; such disorders are considered functional problems and frequently do not have an identifiable anatomic or organic cause Transient lower esophageal sphincter [emedicine.medscape.com]

Functional Dyspepsia

Abstract Objective This study was performed to investigate impaired vagal activity to meal in patients with functional dyspepsia (FD) with delayed gastric emptying (GE). [ncbi.nlm.nih.gov]

gastric emptying group and the non-delayed gastric emptying group. [ncbi.nlm.nih.gov]

KEY MESSAGES: Gastroparesis is characterized by delayed gastric emptying in the absence of mechanical obstruction of the stomach. [ncbi.nlm.nih.gov]

Diabetes Mellitus

A documented delay in gastric emptying is required for the diagnosis of gastroparesis. [doi.org]

Its physiological effect includes weight loss, delayed gastric emptying, and a reduction in both postprandial glucose and glucagon. The primary side effect is nausea. [dx.doi.org]

GLP-1 RAs also delay gastric emptying, and it is reasonable to consider alternative therapies that do not delay gastric emptying. [doi.org]

Autonomic Nervous System Disorder

Oesophageal dysmotility, delayed gastric emptying and autonomic neuropathy correlate to disturbed glucose homeostasis. Diabetologia. 2006 Sep. 49(9):2010-4. [Medline]. [emedicine.medscape.com]

In addition to fainting and falling, other common and disabling conditions associated with autonomic disorders include impaired gastrointestinal motility (gastroparesis, cyclic [med.stanford.edu]

“As a consequence of this, Emily also has gastroparesis, in which the nerves in charge of the stomach don’t work,” Hedspeth said. [masslive.com]

Spinal Muscular Atrophy Type 1

Additional findings include atrophy and fasciculations of the tongue, gastrointestinal problems (gastroesophageal reflux, constipation, and delayed gastric emptying) bulbar [symptoma.com]

Specialty Collaborations & Other Services Gastro-Intestinal & Bowel Function Gastrointestinal problems such as reflux, delayed gastric emptying, and constipation are common [medicalhomeportal.org]

Gastroparesis

Such a phenomenon delays the gastric emptying giving rise to the condition known as gastroparesis. [symptoma.com]

Diabetic gastroparesis occurs when delayed gastric emptying affects individuals with diabetes. [chop.edu]

Gastroparesis—also known as gastric stasis or delayed gastric emptying—is a condition in which your stomach takes too long to empty itself of food. [nm.org]

Hereditary ATTR Amyloidosis

Symptoms include orthostatic hypotension, constipation alternating with diarrhea, nausea, vomiting, delayed gastric emptying, erectile dysfunction, anhydrosis, urinary retention [amyloidosis.co.nz]

[…] numbness and tingling, muscle weakness, impaired balance, difficulty walking) Autonomic dysfunction (e.g., nausea and vomiting, changes in GI motility [diarrhea, constipation, gastroparesis [invitae.com]

Diabetic Neuropathy

Impairment of excitatory pathways affects the contraction of the stomach, which may result in delayed gastric emptying and vomiting of retained food. [ncbi.nlm.nih.gov]

Gastroparesis Assessment Delayed gastric emptying may cause recurrent hypoglycaemia which is often post prandial. [nhshighland.scot.nhs.uk]

Gastroesophageal dysfunction manifests as gastroesophageal reflux disease (GERD) in roughly 30% of diabetes patients. [16,17] Delayed gastric emptying and gastric retention [medscape.com]

Systemic Amyloidosis

Autonomic nervous system involvement by AL amyloidosis can lead to orthostatic hypotension, early satiety as a result of delayed gastric emptying, erectile dysfunction, and [doi.org]

Automatic nervous system involvement is characterized by syncope, erectile dysfunction, gastroparesis, and diarrhea. [bloodjournal.org]

Amyloidosis

Autonomic nervous system involvement by AL amyloidosis can lead to orthostatic hypotension, early satiety as a result of delayed gastric emptying, erectile dysfunction, and [doi.org]

Gastroparesis in a patient with gastric AL amyloidosis. Case Rep Gastroenterol. 2018; 12(2): 317–321. Angiero F, Seramondi R, Magistro S, et al. [journals.viamedica.pl]

Spinal Muscular Atrophy

Chronic Granulomatous Disease

A barium meal showed delayed gastric emptying and luminal thinness of the antrum and pylorus (Figures 1A–D). [frontiersin.org]

Gallbladder cancer Gallbladder pain Gallbladder removal Gallstones Ganglion cyst Gangrene Gastrectomy Gastritis Gastro-oesophageal reflux disease (GORD) Gastroenteritis Gastroparesis [nhs.uk]

An abdominal ultrasound (US) revealed major thickening of the pylorus up to the antrum and the gastric body. [frontiersin.org]

Systemic Scleroderma

[…] on delayed gastric emptying in scleroderma. [ncbi.nlm.nih.gov]

Delayed gastric emptying 0002578 Hyperkeratosis 0000962 Lack of skin elasticity 0100679 Myalgia Muscle ache Muscle pain [ more ] 0003326 Nausea and vomiting 0002017 Skeletal [rarediseases.info.nih.gov]

Isabelle Marie, Guillaume Gourcerol, Anne‐Marie Leroi, Jean‐François Ménard, Hervé Levesque and Philippe Ducrotté, Delayed gastric emptying determined using the 13C–octanoic [doi.org]

Ehlers-Danlos Syndrome

[…] as delayed gastric emptying. [web.archive.org]

gastric emptying/irritable bowel syndrome Beta-blockers for progressive aortic enlargement Analgesics for chronic pain Pain-oriented counseling Exercise to improve muscle [symptoma.com]

Delayed gastric emptying, orthostatic hypotension (sometimes with associated syncope), and different kinds of headaches may be seen. [verywellhealth.com]

Diabetes Mellitus Type 2

(→ delayed gastric emptying, risk of postprandial hypoglycemia ): nausea, abdominal bloating, loss of appetite, early satiety Diarrhea, constipation, incontinence Treatment [amboss.com]

It also delays gastric emptying and suppresses appetite through central pathways. [clevelandclinicmeded.com]

Other Glucose-Lowering Pharmacologic Agents Pramlintide, an amylin analog, is an agent that delays gastric emptying, blunts pancreatic secretion of glucagon, and enhances [frontiersin.org]

Diabetes Mellitus Type 1

(→ delayed gastric emptying, risk of postprandial hypoglycemia): nausea, abdominal bloating, loss of appetite, early satiety Diarrhea, constipation, incontinence Treatment [amboss.com]

These include impotence, orthostatic hypotension, delayed gastric emptying, diarrhea or constipation, and asymptomatic retention of urine in the bladder. [medical-dictionary.thefreedictionary.com]

It is important that hypoglycemia be treated with a source of pure carbohydrate, as protein and fat ingestion slows gastric emptying which would delay the correction of hypoglycemia [clinicaladvisor.com]

Eating Disorder

BACKGROUND: Anorexia nervosa (AN) is a chronic disorder that can overlap with lower esophageal sphincter failure and delayed gastric emptying. [ncbi.nlm.nih.gov]

Crossref, PubMed, Google Scholar Hayes M.R, Moore R.L, Shah S.M& Covasa M. 2004 5-HT3 receptors participate in CCK-induced suppression of food intake by delaying gastric emptying [doi.org]

GASTROINTESTINAL SYSTEM Slowed digestion known as gastroparesis. [nationaleatingdisorders.org]

Parkinson Disease

Smoking delays gastric emptying of solids. Gut. 1989;30:50–3. PubMed PubMed Central View Article Google Scholar Scott AM, Kellow JE, Eckersley GM, Nolan JM, Jones MP. [doi.org]

Delayed gastric emptying and enteric nervous system dysfunction in the rotenone model of Parkinson’s disease. Exp Neurol 218(1):154-161 19409896. [dx.doi.org]

Delayed gastric emptying and enteric nervous system dysfunction in the rotenone model of Parkinson’s disease. [ncbi.nlm.nih.gov]

Diabetic Enteropathy

gastric emptying. [grantome.com]

gastric emptying, associated with diabetic enteropathy. [d-net.idf.org]

Gastric outlet obstruction and medication-induced gastroparesis should be ruled out as the cause of delayed gastric emptying. [consultant360.com]

Hypothyroidism

Kim PJ, Sachmechi I (2015) Levothyroxine malabsorption induced by diabetic gastroparesis exacerbated during pregnancies: effect of intramuscular levothyroxine injections and [dx.doi.org]

[…] pylori infection, inflammatory bowel disease (IBD), celiac disease, lactose intolerance, atrophic body gastritis (ABG), gastric bypass, biliary pancreatic diversion, and gastroparesis [dx.doi.org]

Cannabinoid Hyperemesis Syndrome

General Prevention Cannabis cessation or avoidance Commonly Associated Conditions Substance use disorders Delayed gastric emptying -- To view the remaining sections of this [unboundmedicine.com]

CB1 receptor activation reduces gastric motility and results in delayed gastric emptying in rat models [44,45]. [ncbi.nlm.nih.gov]

General Prevention Cannabis cessation or avoidance Commonly Associated Conditions Substance use disorders Delayed gastric emptying There's more to see -- the rest of this [unboundmedicine.com]

Autoimmune Pangastritis

emptying, a consistent delaying effect of these drugs on gastric emptying of solid meals has been shown. [32] Albeit the hypochlorhydria induced by proton pump inhibitors [journals.lww.com]

Previously, in atrophic gastritis, a role of gastric emptying has been investigated, showing a delayed emptying both in the autoimmune [28] and nonautoimmune atrophic gastritis [journals.lww.com]

[29] In addition, the reduced gastric acid secretion seems to be associated with the presence of dyspepsia [30] and more recently, a Japanese study conducted on dyspeptic [journals.lww.com]

Dyspepsia

Causes of Delayed Gastric Emptying [23]. 4. [intechopen.com]

Causes of Delayed Gastric Emptying [23]. Advertisement 4. [intechopen.com]

Another notable finding was the lack of efficacy in those with delayed gastric emptying suggesting different disease mechanisms may be in play in those with versus without [healio.com]

Partial Pyloric Obstruction

Some surgeons argue that prophylactic gastrojejunostomy may increase postoperative morbidity, primarily due to delayed gastric emptying. [emedicine.medscape.com]

A degree of pylorospasm is common in infancy and is responsible for some delay in gastric emptying. The pylorus, however, appears sonographically normal. [radiopaedia.org]

[…] by gastroparesis and coexisting diseases with delayed gastric emptying [ 3 ]. [academic.oup.com]

Pyloric Obstruction

Figure 5: Showing delayed gastric emptying after about 1 hour of contrast seen in the stomach. [scitechnol.com]

Some surgeons argue that prophylactic gastrojejunostomy may increase postoperative morbidity, primarily due to delayed gastric emptying. [emedicine.medscape.com]

gastric emptying. [aon.or.kr]

Aspiration of Gastric Contents

Pathology of the gastrointestinal tract delays gastric emptying, ensuring a ‘full stomach’, and impairs the function of the LOS. [ceaccp.oxfordjournals.org]

There is little evidence that trauma increases the risk of aspiration although a number of factors associated with trauma are known to delay gastric emptying. [cambridge.org]

Feeding Intolerance Patients at risk for delayed gastric emptying include those with gastroparesis, poorly controlled diabetes mellitus, gastric outlet obstruction, ileus, [todaysdietitian.com]

Postoperative Pancreatitis

gastric emptying compared with the patients without delayed gastric emptying. [scipers.com]

Surgical (9/12 vs. 5/27; P =0.001) but not medical complications occurred more often in the delayed gastric emptying group. [link.springer.com]

Postoperative pancreatic fistula, delayed gastric emptying, postpancreatectomy hemorrhage, biliary fistula, wound infection, postoperative pancreatitis. [clinicaltrials.gov]

Intestinal Hypomotility

23-26% of functional dyspeptic patients had delayed gastric emptying [ 20, 21 ]. [bmcgastroenterol.biomedcentral.com]

Intro / Digestion / Who gets GP / What happens / Symptoms / Dx / Mild forms / Tx Theories related to delayed gastric emptying: Gastroparesis is delayed gastric emptying (emptying [digestivedistress.com]

Most published literature describes gastroparesis as delayed gastric emptying without a mechanical obstruction. [chop.edu]