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328 Possible Causes for Delayed Ossification

  • Cleidocranial Dysplasia

    It is characterised by macrocephaly with persistently open sutures, absent or hypoplastic clavicles, dental anomalies, and delayed ossification of the pubic bones.[ncbi.nlm.nih.gov] At week 13 6, a 2D ultrasound examination revealed a fetus with severely delayed ossification of the vertebral spine.[ncbi.nlm.nih.gov] Cleidocranial dysplasia is a hereditary congenital disorder that results in delayed ossification of midline structures, and is caused by mutations in the RunX2 (runt-related[ncbi.nlm.nih.gov]

  • Scoliosis

    Calcein staining revealed that mapk7-knockdown delayed the ossification of the vertebrae.[ncbi.nlm.nih.gov]

  • Pregnancy

    […] fetal growth, osteopenia, impaired fetal bone ossification, craniotabes, hypocalcemia, tetany, heart disease, enamel hypoplasia and decreased statural growth velocity. 25[doi.org] […] of vitamin D deficiency include rickets, osteomalacia and osteoporosis. 24, 25 Additionally, low vitamin D during the fetal and neonatal period has been associated with delayed[doi.org]

  • Spondylocarpotarsal Synostosis

    ossification of many epiphyses as well as in carpal ossification Lordosis Odontoid hypoplasia Show images Pes planus Show images Scoliosis Show images Thorax The thoracic[datagenno.com] Unlike other documented cases, radiographs of our patient at 5(1/2) years of age show delay in ossification of many of the epiphyses in addition to delay in carpal ossification[ncbi.nlm.nih.gov] […] lunate-triquetrum Decreased range of motion at elbows Postaxial polydactyly Show images Tarsal synostosis Ocular Ocular hypertelorism Show images Oral Cleft palate Show images Skeletal Delayed[datagenno.com]

  • Hand-Foot-Genital Syndrome

    ossification of wrist bones.[ncbi.nlm.nih.gov] Limb anomalies include short first metacarpals of normal thickness, small distal phalanges of the thumbs, short middle phalanges of the fifth fingers, and fusion or delayed[ncbi.nlm.nih.gov]

  • Multiple Epiphyseal Dysplasia

    ossification of femoral epiphyses.[ncbi.nlm.nih.gov] Introduction A form of dwarfism characterized by irregular, delayed ossification at multiple epiphyses spectrum of disorders with a spectrum of phenotypes Epidemiology prevalence[orthobullets.com] There is a mild version (‘ribbing’) and a more typical, severe, form (‘Fairbanks’) Pathophysiology Irregular, delayed, ossification of multiple epiphyses.[slideshare.net]

  • Spondyloepiphyseal Dysplasia

    […] of the pubis wide Y cartilage coxa vara of varying severity delayed ossification of the femoral head MRI indications cervical instability symptoms of myelopathy findings[orthobullets.com] […] is determined by the degree of abnormality), 6) normal hands and feet although delayed appearance of the ossification centers, and 7) moderate kyphoscoliosis and lumbar lordosis[advancedradteaching.com] ossification of the femoral heads with degenerative changes).[orpha.net]

  • Moderate and Severe Traumatic Brain Injury

    Heterotopic ossification may result in functional impairment, and patients may require surgical excision.[emedicine.medscape.com] The risks and benefits of these drugs in managing established heterotopic ossification should be assessed.[emedicine.medscape.com] To minimize risk of recurrence, surgical excision has traditionally been delayed 12-18 months to allow the heterotopic bone to mature.[emedicine.medscape.com]

  • Spondyloepiphyseal Dysplasia Congenita

    ossification of the femoral heads with degenerative changes).[orpha.net] Delayed ossification in the epiphyses and the os pubis is common.[disorders.eyes.arizona.edu] […] of capital femoral epiphysis is delayed & often does not appear until age 5 years; - combination of delayed ossification, high riding femur, and limited abduction often gives[wheelessonline.com]

  • Kniest Dysplasia

    Fetal MRI findings included enlarged hyaline cartilaginous structures with abnormally high T2 signal intensity, delayed ossification of the pubic and ischial bones, and platyspondyly[ncbi.nlm.nih.gov] General Described features include non-ossified epiphyses absent ossification of the pubic bones delayed ossification of the femoral heads flatted ovoid vertebral bodies [radiopaedia.org]

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