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1,433 Possible Causes for Delayed Speech Development, Profound Psychomotor Developmental Delay

  • Mental Retardation

    Three siblings in a consanguineous Pakistani family presented with profound developmental delay, severe ID, no speech, psychomotor delay, and postnatal microcephaly.[ncbi.nlm.nih.gov] In addition to eye abnormalities, affected individuals may also have neurological abnormalities including diminished muscle tone (hypotonia), delays in speech development,[rarediseases.org] Children who are moderately retarded show noticeable delays in developing speech and motor skills.[humanillnesses.com]

  • Congenital Deafness

    This results in delayed speech/language development, social problems and academic difficulties.[pamf.org] Parental concerns about possible hearing loss or observed delays in speech development require auditory screening in any child.[ncbi.nlm.nih.gov] If they have a hearing loss that is undetected and untreated, they can miss much of the speech and language around them.[pamf.org]

    Missing: Profound Psychomotor Developmental Delay
  • Mucopolysaccharidosis

    […] in speech development may occur in conjunction with cognitive decline in severely affected children, and many patients never learn to speak in full sentences. 9,14 Patients[touchneurology.com] The patient developed normally until the age of 2 years when he was referred to a paediatric neurologist for suspected motor and speech delay.[ncbi.nlm.nih.gov] Otitis prone children are at risk of developing delayed speech and language development due to conductive hearing loss caused by recurrent AOM with effusion [34].[smw.ch]

    Missing: Profound Psychomotor Developmental Delay
  • MELAS Syndrome

    Medical records showed that significantly more often than controls, carriers had delayed motor or speech development and reading or learning problems.[journals.lww.com]

    Missing: Profound Psychomotor Developmental Delay
  • Mucopolysaccharidosis 2

    […] in speech development may occur in conjunction with cognitive decline in severely affected children, and many patients never learn to speak in full sentences. 9,14 Patients[touchneurology.com] Coarse facial features, hepatomegaly, hearing difficulties and delayed speech development are common. Life expectancy in attenuated forms may be limited to Figure 4b ).[touchophthalmology.com] The parents and the pediatrician had agreed to delay subspecialty referral until the effect of restored hearing on the boy’s speech development could be assessed.[consultant360.com]

    Missing: Profound Psychomotor Developmental Delay
  • Down Syndrome

    , particularly those with the greatest delays in speech and language development.[dseinternational.org] Most children and adults with Down syndrome continue to develop good social skills and appropriate social behaviour, though a significant minority may develop difficult behaviours[web.archive.org] Apart from hearing problems, children with DS have delayed speech development [ 21 ].[ncbi.nlm.nih.gov]

    Missing: Profound Psychomotor Developmental Delay
  • SHORT Syndrome

    We describe a boy with the manifestations of the SHORT syndrome: lipoatrophy, delayed speech development, minor facial anomalies, clinodactyly, and short stature.[ncbi.nlm.nih.gov] […] in speech development and in dental eruption.[ncbi.nlm.nih.gov] Mild cognitive disorders have been described as well as delayed speech development can occur in childhood [ 1, 2, 3, 5, 6 ].[ijponline.biomedcentral.com]

    Missing: Profound Psychomotor Developmental Delay
  • Mucopolysaccharidosis 3

    At this time, developmental abnormalities begin to manifest in the form of delayed speech development or autistic behaviour patterns.[socialstyrelsen.se] At diagnosis, speech development is generally much more delayed than motor development.[oapublishinglondon.com] After a period of normal development, phase 1 is marked by an early childhood presentation of speech and psychomotor delays with or without behavioral problems.[invitae.com]

    Missing: Profound Psychomotor Developmental Delay
  • Pallister W Syndrome

    speech development or no speech Abnormal skin pigmentation (see photos) Repetitive behaviors (stereotypy) Difficulties with walking Feeding difficulties Impaired vision Hearing[forgottendiseases.org] Hearing loss, lack of speech development Issues related to the face and skull: Sparse scalp hair, eyebrows and eyelashes Coarse facial features Large forehead Pronounced[dovemed.com] All had delayed psychomotor development with limited speech, dysarthria, and poor somatic growth.[findzebra.com]

    Missing: Profound Psychomotor Developmental Delay
  • Histidinemia

    Symptoms include organic acids in urine, mental retardation, and delayed speech development. Treatment includes a low-histamine diet.[smpdb.ca] Decrease in hearing is sometimes noted what in a nek-swarm of degree the delay of intellectual development and defects of the speech can be connected with.[bigmed.info]

    Missing: Profound Psychomotor Developmental Delay

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