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35 Possible Causes for Delayed Wound Healing, Easy Bruising, Hemarthrosis

  • Hemophilia

    , MD -6.60 (95% CI -9.32 to -3.88) (low quality evidence) and mean number of joints that had hemarthrosis, MD -0.90 (95% CI -1.36 to -0.44).[ncbi.nlm.nih.gov] The main symptoms of hemophilia are excessive bleeding and easy bruising. Blood tests can tell if you have it.[nlm.nih.gov] The major signs and symptoms of hemophilia are excessive bleeding and easy bruising. Excessive Bleeding The extent of bleeding depends on how severe the hemophilia is.[web.archive.org]

  • Factor XIII Deficiency

    A 47-year-old man with congenital factor XIII deficiency developed recurrent hemarthrosis of the right ankle. He had radiologic evidence of permanent joint damage.[ncbi.nlm.nih.gov] Other signs and symptoms of inherited factor XIII deficiency include nosebleeds, bleeding of the gums, easy bruising, problems with wound healing, bleeding after surgery,[ghr.nlm.nih.gov] They also had prolonged umbilical cord bleeding and history of delayed wound healing. Since childhood, they have been developing spontaneous ecchymotic spots.[ncbi.nlm.nih.gov]

  • Hemophilia B

    The percentage of patients with either 10-50 or more than 50 hemarthrosis was greater in hemophilia A than in hemophilia B (P Copyright Ferrata Storti Foundation.[ncbi.nlm.nih.gov] Symptoms include easy bruising, urinary tract bleeding (hematuria), nosebleeds (epistaxis), and bleeding into joints (hemarthrosis).[en.wikipedia.org] Moderate or mild deficiency is associated with prolonged bleeding after tooth extractions, surgery, or injuries and recurrent or delayed wound healing.[ltd.aruplab.com]

  • Hemophilia A

    , MD -6.60 (95% CI -9.32 to -3.88) (low quality evidence) and mean number of joints that had hemarthrosis, MD -0.90 (95% CI -1.36 to -0.44).[ncbi.nlm.nih.gov] Affected individuals suffer hemorrhage into joints and muscles, easy bruising, and prolonged bleeding from wounds.[medicinenet.com] Moderate to mild deficiency is associated with prolonged bleeding after tooth extractions, surgery, or injuries and recurrent or delayed wound healing.[ltd.aruplab.com]

  • Hereditary Factor XIII A Subunit Deficiency

    Bleeding into joint spaces (hemarthrosis) occasionally occurs.[icdlist.com] Other features included haematoma formation, easy bruising, post-traumatic bleeding, delayed wound healing, gastrointestinal bleeding and epistaxis.[jpma.org.pk] Hemarthrosis is not common. Pregnant women with this disorder commonly have miscarriages.[clinicaladvisor.com]

  • Ehlers Danlos Syndrome

    Soft tissue findings multiple ovoid calcifications ( ectopic ossification 2 Skeletal findings hemarthrosis (especially knees) recurrent dislocation: including spontaneous[radiopaedia.org] Skin hyperextensibility, easy bruising, tissue fragility, atrophic scars, loss of muscle tone, Kyphoscoliosis, and osteopenia (bones which are less dense than normal) are[rarediseases.about.com] wound healing.[symptoma.com]

  • Scurvy

    Examination revealed hemarthrosis, skin findings characteristic of scurvy, and deficiency in vitamin C on laboratory analysis.[ncbi.nlm.nih.gov] The clinical manifestations of follicular hyperkeratosis, perifollicular petechiae, corkscrew hairs, and easy bruising are due to defective collagen synthesis and can be mistaken[ncbi.nlm.nih.gov] wound healing.[theconversation.com]

  • Infantile Scurvy

    Differential diagnoses include traumatic injury, septic arthritis/osteomyelitis, hemophilic hemarthrosis, congenital syphilis, leukemic infiltration and other painful conditions[indianpediatrics.net] Perifollicular petechiae and easy bruising. J Fam Pract. 2016 Dec. 65 (12):927-930. [Medline]. [Full Text]. Ragunatha S, Inamadar AC, Palit A, et al.[emedicine.medscape.com] The very important effect of vitamin C deficiency is delayed wound healing. There may be severe bleeding with later superimposed infection.[pathopedia-india.com]

  • Anemia

    Purpura and petechiae suggest platelet disorders, and hemarthrosis may be due to hemophilia.[emedicine.com] bruising Milky nipple discharge (called galactorrhea ) Early puberty (mostly seen in children with severe, longstanding disease) Delayed puberty (often the first obvious[verywell.com] […] growth and development Impaired wound and tissue healing The symptoms of anemia may resemble other blood disorders or medical problems.[chop.edu]

  • Congenital Factor II Deficiency

    Symptoms of Rare Clotting Factor Deficiencies Common symptoms nosebleeds (epistaxis) easy bruising heavy or prolonged menstrual bleeding (menorrhagia) bleeding into joints (hemarthrosis[wfh.org] Common clinical signs include epistaxis, menorrhagia, oral cavity bleedings, mucosal bleeding, soft tissue bleeding, hemarthroses, easy bruising, and prolonged bleeding after[orpha.net] The impaired cross-linking of extracellular matrix proteins at sites of wound healing or placental implantation can lead to abnormalities in these processes, resulting in[emedicine.medscape.com]

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