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48 Possible Causes for Delayed Wound Healing, Easy Bruising, Hemarthrosis

  • Hemophilia B

    Moderate or mild deficiency is associated with prolonged bleeding after tooth extractions, surgery, or injuries and recurrent or delayed wound healing.[ltd.aruplab.com] […] less than 10 hemarthrosis was higher in hemophilia B (P 0.0001).[ncbi.nlm.nih.gov] bruising, excessive bleeding after surgery, trauma, dental procedures or circumcision; epistaxis, poor wound healing, intracranial hemorrhage, scalp hematoma, development[pathologyoutlines.com]

  • Hemophilia A

    , MD -6.60 (95% CI -9.32 to -3.88) (low quality evidence) and mean number of joints that had hemarthrosis, MD -0.90 (95% CI -1.36 to -0.44).[ncbi.nlm.nih.gov] Affected individuals suffer hemorrhage into joints and muscles, easy bruising, and prolonged bleeding from wounds.[medicinenet.com] Moderate to mild deficiency is associated with prolonged bleeding after tooth extractions, surgery, or injuries and recurrent or delayed wound healing.[ltd.aruplab.com]

  • Factor XIII Deficiency

    A 47-year-old man with congenital factor XIII deficiency developed recurrent hemarthrosis of the right ankle. He had radiologic evidence of permanent joint damage.[ncbi.nlm.nih.gov] They also had prolonged umbilical cord bleeding and history of delayed wound healing. Since childhood, they have been developing spontaneous ecchymotic spots.[ncbi.nlm.nih.gov] A review of the literature revealed that hemarthrosis is not a rare manifestation of factor XIII deficiency; however, destructive changes in the joints are relatively uncommon[ncbi.nlm.nih.gov]

  • Hemophilia

    , MD -6.60 (95% CI -9.32 to -3.88) (low quality evidence) and mean number of joints that had hemarthrosis, MD -0.90 (95% CI -1.36 to -0.44).[ncbi.nlm.nih.gov] Other symptoms include frequent episode of bleeding from gums, nose and mild cuts, and easy bruising.[symptoma.com] Biodistribution analysis revealed an initial temporary entrapment of the cells in the lungs, followed by homing to the liver and to a joint afflicted with hemarthrosis.[ncbi.nlm.nih.gov]

  • Scurvy

    Examination revealed hemarthrosis, skin findings characteristic of scurvy, and deficiency in vitamin C on laboratory analysis.[ncbi.nlm.nih.gov] The clinical manifestations of follicular hyperkeratosis, perifollicular petechiae, corkscrew hairs, and easy bruising are due to defective collagen synthesis and can be mistaken[ncbi.nlm.nih.gov] wound healing.[theconversation.com]

  • Infantile Scurvy

    The very important effect of vitamin C deficiency is delayed wound healing. There may be severe bleeding with later superimposed infection.[pathopedia-india.com] Differential diagnoses include traumatic injury, septic arthritis/osteomyelitis, hemophilic hemarthrosis, congenital syphilis, leukemic infiltration and other painful conditions[indianpediatrics.net] Skin changes with roughness, easy bruising and petechiae, gum disease, loosening of teeth, poor wound healing, and emotional changes occur.[medcaretips.com]

  • Congenital Afibrinogenemia

    Despite the absolute incoagulability of afibrinogenemic blood, this type of hemorrhagic diathesis is not accompanied by hemarthrosis.[pediatrics.aappublications.org] bruising), or formation of blood clots The following article link will help you understand fibrinogen blood test: What are some Useful Resources for Additional Information[dovemed.com] Common signs and symptoms include: Delayed wound healing Rupture of surgical sutures Dead or dying skin (necrosis) In women, miscarriage, stillbirths, and excessive bleeding[rarebleedingdisorders.com]

  • Hypofibrinogenemia

    So, in congenital hypofibrinogenemia, a joint swelling might be a resultant of an acute osteomyelitis, not mere hemarthrosis.[ncbi.nlm.nih.gov] bruising, nose and mouth bleeds, and soft tissue bleeds are also common; joint bleeding is relatively uncommon Women with afibinogenemia have an increased risk of spontaneous[ilbcdi.org] wound healing.[clinlabnavigator.com]

  • Hereditary Dysfibrinogenemia

    Bleeding into joint spaces (hemarthrosis) occasionally occurs.[icdlist.com] More than half of the probands had experienced one or more undue bleeding episode, easy bruising being by far the most common.[journals.lww.com] wound healing.[clinlabnavigator.com]

  • Purpura

    […] and duration Exposures to medications, drugs or chemicals Antecedent illnesses Associated symptoms Abdominal pain Hematochezia Arthralgias Fever Confusion Mucosal bleeding Hemarthrosis[clinicaladvisor.com] The history usually reveals no other abnormal bleeding, but easy bruising may be present in family members. Serious bleeding does not occur.[merckmanuals.com] .  Deficiency causes weakened collagen strands predisposing to capillary fragility and delayed wound healing.  History helpsPERIFOLLICULAR HEMORRHAGES IN 31.[slideshare.net]

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