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93 Possible Causes for Delayed Wound Healing, Easy Bruising, Intracranial Hemorrhage

  • Hemophilia A

    Affected individuals suffer hemorrhage into joints and muscles, easy bruising, and prolonged bleeding from wounds.[] Moderate to mild deficiency is associated with prolonged bleeding after tooth extractions, surgery, or injuries and recurrent or delayed wound healing.[] Untreated patients are at risk for developing joint deterioration, disability, and intracranial hemorrhage.[]

  • Hemophilia B

    bruising, excessive bleeding after surgery, trauma, dental procedures or circumcision; epistaxis, poor wound healing, intracranial hemorrhage, scalp hematoma, development[] Moderate or mild deficiency is associated with prolonged bleeding after tooth extractions, surgery, or injuries and recurrent or delayed wound healing.[] Even if bleeding occurs, it rarely becomes life-threatening, such as in intracranial hemorrhage (ICH).[]

  • Hemophilia

    Other symptoms include frequent episode of bleeding from gums, nose and mild cuts, and easy bruising.[] However, as he suffered from intracranial hemorrhage at the age of 1 year, he underwent first ITI at the age of 1 year.[] Patients bleed into tissues (eg, hemarthroses, muscle hematomas, retroperitoneal hemorrhage) following minimal trauma; fatal intracranial hemorrhage may occur.[]

  • Ehlers Danlos Syndrome

    bruising, arterial, intestinal, and/or uterine fragility.[] wound healing.[] Severe complications included mainly hematomas (53%), frequently reported in musculocontractural and classical-like EDS; intracranial hemorrhages (18%), with a high risk in[]

  • Ehlers-Danlos Syndrome Type 4

    bruising, bruising without trauma, and fragile arteries, intestine, and/or uterus.[] The oral manifestations include increased mucosal fragility, delayed wound healing, early onset generalized periodontitis and temporomandibular joint hypermobility.[] wound healing Kyphoscoliotic EDS Kyphoscoliotic EDS (kEDS) is rare.[]

  • Factor XIII Deficiency

    They also had prolonged umbilical cord bleeding and history of delayed wound healing. Since childhood, they have been developing spontaneous ecchymotic spots.[] We report an infant with Factor XIII deficiency who had 2 seemingly spontaneous intracranial hemorrhages.[] Intracranial hemorrhage (ICH) is one of the most severe and life-threatening manifestations occurring in the patients with factor XIII (F XIII) deficiency.[]

  • Pseudoxanthoma Elasticum

    […] susceptibility Bruise easily Easy bruisability Easy bruising Once the ABCC6 mutations that cause PXE in a family are identified, unaffected relatives may be tested for the[] Intracranial hemorrhage can occur in the absence of aneurysm, and gastrointestinal hemorrhage is common.[] […] aneurysm formation. - Intracranial hemorrhage can occur in the absence of aneurysm. - Peripheral arterial vascular disease can lead to intermittent leg claudication. 8.[]

  • Congenital Afibrinogenemia

    bruising), or formation of blood clots The following article link will help you understand fibrinogen blood test: What are some Useful Resources for Additional Information[] Common signs and symptoms include: Delayed wound healing Rupture of surgical sutures Dead or dying skin (necrosis) In women, miscarriage, stillbirths, and excessive bleeding[] Although congenital afibrinogenemia can commonly present with hemorrhage from the umbilical cord at birth, or with spontaneous mucosal or intracranial hemorrhage in the neonatal[]

  • Loeys Dietz Syndrome Type 1

    bruising Dystrophic FIGURE 38-3 Thin, translucent skin with large scars in a patient with Loeys Dietz syndrome (LDS).[] These patients have velvety and translucent skin with easy bruising and delayed wound healing.[] , 3 had hydrocephalus, 4 had dural ectasia, 2 had a Chiari malformation, and 1 had intracranial hemorrhage as a complication of vascular dissection.[]

  • May-Hegglin Anomaly

    One of her children had easy bruising.[] On another line, none of the patients experienced complications related to delayed wound healing.[] The fetuses of such patients run the risk of intracranial hemorrhage in utero and during the early neonatal period following vaginal delivery.[]

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