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17 Possible Causes for Delayed Wound Healing, Easy Bruising, Partial Thromboplastin Time Increased

  • Hemophilia

    Plasma concentrations of emicizumab increased in a dose-dependent manner. Activated partial-thromboplastin times remained short throughout the study.[doi.org] The main symptoms of hemophilia are excessive bleeding and easy bruising. Blood tests can tell if you have it.[nlm.nih.gov] The major signs and symptoms of hemophilia are excessive bleeding and easy bruising. Excessive Bleeding The extent of bleeding depends on how severe the hemophilia is.[web.archive.org]

  • Liver Failure

    Kidney disease or failure Easy bruising and severe bleeding. This happens when the liver stops making proteins that are needed for your blood to clot. Type 2 diabetes.[hopkinsmedicine.org] Previous studies have found that binge drinking delays wound healing, increases blood loss and makes us more prone to pneumonia and other infections.[dailymail.co.uk] bruising and abnormal bleeding Confusion or problems thinking Pale or clay-colored stools Your health care provider will do a physical exam to look for: An enlarged liver[nlm.nih.gov]

  • Hemophilia A

    This is identified by an increased partial thromboplastin time in the context of a healthy prothrombin time and bleeding time.[news-medical.net] Affected individuals suffer hemorrhage into joints and muscles, easy bruising, and prolonged bleeding from wounds.[medicinenet.com] Moderate to mild deficiency is associated with prolonged bleeding after tooth extractions, surgery, or injuries and recurrent or delayed wound healing.[ltd.aruplab.com]

  • Hemophilia B

    Symptoms include easy bruising, urinary tract bleeding (hematuria), nosebleeds (epistaxis), and bleeding into joints (hemarthrosis).[en.wikipedia.org] Moderate or mild deficiency is associated with prolonged bleeding after tooth extractions, surgery, or injuries and recurrent or delayed wound healing.[ltd.aruplab.com] Essentials Disorders of hemostasis can lead to delayed and defective wound healing.[ncbi.nlm.nih.gov]

  • Alcoholic Hepatitis

    […] deficiency) Endocrine Gynaecomastia Testicular atrophy Loss of body hair Signs of ‘pseudo- Cushings ’ (red face, hump, striae) Face /skin Parotid enlargement Spider naevi Easy[almostadoctor.co.uk] Recurrent hepatic encephalopathy was only seen in group I (pentoxifylline), while oral thrush, worsening of ascites, impaired glucose tolerance, delayed wound healing and[wjgnet.com] bruising and abnormal bleeding Confusion or problems thinking Pale or clay-colored stools Your health care provider will do a physical exam to look for: An enlarged liver[nlm.nih.gov]

  • Hereditary Coagulopathy

    Antiphospholipid syndrome Antiphospholipid syndrome (lupus anticoagulant) [6, 7] screening tests are as follows: Activated partial thromboplastin time (aPTT) Prothrombin time[emedicine.medscape.com] Easy bruising and abnormal bleeding are common symptoms in the primary care setting that may present as excessive bruising when injured, or as epistaxis, menorrhagia, or prolonged[aafp.org] wound.[scielo.br]

  • Hereditary Dysfibrinogenemia

    More than half of the probands had experienced one or more undue bleeding episode, easy bruising being by far the most common.[journals.lww.com] wound healing.[clinlabnavigator.com] Factor X deficiency commonly causes nosebleeds, easy bruising, bleeding under the skin, bleeding of the gums, blood in the urine (hematuria), and prolonged or excessive bleeding[icdlist.com]

  • Congenital Afibrinogenemia

    Aside from the fact that women have similar symptoms to men with bleeding disorders (recurrent nosebleeds, easy bruising, bleeding from the digestive or urinary tract and[rarediseases.info.nih.gov] Common signs and symptoms include: Delayed wound healing Rupture of surgical sutures Dead or dying skin (necrosis) In women, miscarriage, stillbirths, and excessive bleeding[rarebleedingdisorders.com] Afibrinogenemia Common Symptoms nosebleeds (epistaxis) easy bruising heavy or prolonged menstrual bleeding (menorrhagia) muscle bleeds bleeding into joints (hemarthrosis)[wfh.org]

  • Acquired Factor XIII Deficiency

    Factor XIII deficiency should be considered when a patient with excessive bleeding has both normal protime (PT) and activated partial thromboplastin time (aPTT). 6 Congenital[beta.labcorp.com] See Bleeding Symptoms of Rare Clotting Factor Deficiencies Common symptoms nosebleeds (epistaxis) easy bruising heavy or prolonged menstrual bleeding (menorrhagia) bleeding[wfh.org] Other features included haematoma formation, easy bruising, post-traumatic bleeding, delayed wound healing, gastrointestinal bleeding and epistaxis.[jpma.org.pk]

  • Purpura

    (PT prothrombin time; aPTT activated partial thromboplastin time) Adapted with permission from Cohen AR. Rash—purpura. In: Fleisher GA, LudwigS, et al., eds.[aafp.org] The history usually reveals no other abnormal bleeding, but easy bruising may be present in family members. Serious bleeding does not occur.[merckmanuals.com] .  Deficiency causes weakened collagen strands predisposing to capillary fragility and delayed wound healing.  History helpsPERIFOLLICULAR HEMORRHAGES IN 31.[slideshare.net]

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