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24 Possible Causes for Delayed Wound Healing, Easy Bruising, Partial Thromboplastin Time Increased

  • Hemophilia A

    This is identified by an increased partial thromboplastin time in the context of a healthy prothrombin time and bleeding time.[] Affected individuals suffer hemorrhage into joints and muscles, easy bruising, and prolonged bleeding from wounds.[] Moderate to mild deficiency is associated with prolonged bleeding after tooth extractions, surgery, or injuries and recurrent or delayed wound healing.[]

  • Hemophilia B

    bruising, excessive bleeding after surgery, trauma, dental procedures or circumcision; epistaxis, poor wound healing, intracranial hemorrhage, scalp hematoma, development[] Moderate or mild deficiency is associated with prolonged bleeding after tooth extractions, surgery, or injuries and recurrent or delayed wound healing.[] Essentials Disorders of hemostasis can lead to delayed and defective wound healing.[]

  • Liver Failure

    Previous studies have found that binge drinking delays wound healing, increases blood loss and makes us more prone to pneumonia and other infections.[] partial thromboplastin time (PTT) become prolonged when plasma coagulation components are diluted to less than 30%, and abnormal bleeding occurs when they are less than 17%[] Kidney disease or failure Easy bruising and severe bleeding. This happens when the liver stops making proteins that are needed for your blood to clot. Type 2 diabetes.[]

  • Hemophilia

    Other symptoms include frequent episode of bleeding from gums, nose and mild cuts, and easy bruising.[] The main symptoms of hemophilia are excessive bleeding and easy bruising. Blood tests can tell if you have it.[] Other symptoms of hemophilia include easy bruising, prolonged nosebleeds or vomiting of blood.[]

  • Hereditary Dysfibrinogenemia

    wound healing.[] • Serial thrombotic episodes Laboratory abnormalities • Modestly increased prothrombin time in some patients • Shortened or lengthened partial thromboplastin time • Normal[] More than half of the probands had experienced one or more undue bleeding episode, easy bruising being by far the most common.[]

  • Congenital Afibrinogenemia

    bruising), or formation of blood clots The following article link will help you understand fibrinogen blood test: What are some Useful Resources for Additional Information[] Common signs and symptoms include: Delayed wound healing Rupture of surgical sutures Dead or dying skin (necrosis) In women, miscarriage, stillbirths, and excessive bleeding[] Afibrinogenemia Common Symptoms nosebleeds (epistaxis) easy bruising heavy or prolonged menstrual bleeding (menorrhagia) muscle bleeds bleeding into joints (hemarthrosis)[]

  • Hypofibrinogenemia

    Subsequently she developed coagulation disorders as substantiated by increased international normalized ratio (INR), prolonged partial thromboplastin time (aPTT), and severe[] bruising, nose and mouth bleeds, and soft tissue bleeds are also common; joint bleeding is relatively uncommon Women with afibinogenemia have an increased risk of spontaneous[] wound healing.[]

  • May-Hegglin Anomaly

    A full coagulation panel, including prothrombin time (PT, often increased proportionately to the severity of thrombocytopenia) and activated partial thromboplastin time (aPTT[] One of her children had easy bruising.[] On another line, none of the patients experienced complications related to delayed wound healing.[]

  • Acquired Factor XIII Deficiency

    Factor XIII deficiency should be considered when a patient with excessive bleeding has both normal protime (PT) and activated partial thromboplastin time (aPTT). 6 Congenital[] See Bleeding Symptoms of Rare Clotting Factor Deficiencies Common symptoms nosebleeds (epistaxis) easy bruising heavy or prolonged menstrual bleeding (menorrhagia) bleeding[] Other features included haematoma formation, easy bruising, post-traumatic bleeding, delayed wound healing, gastrointestinal bleeding and epistaxis.[]

  • Purpura

    (PT prothrombin time; aPTT activated partial thromboplastin time) Adapted with permission from Cohen AR. Rash—purpura. In: Fleisher GA, LudwigS, et al., eds.[] The history usually reveals no other abnormal bleeding, but easy bruising may be present in family members. Serious bleeding does not occur.[] .  Deficiency causes weakened collagen strands predisposing to capillary fragility and delayed wound healing.  History helpsPERIFOLLICULAR HEMORRHAGES IN 31.[]

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