Create issue ticket

461 Possible Causes for Dementia, Extremity Ataxia, Progressive Polyneuropathy

  • Vitamin B12 Deficiency

    peripheral neuropathy, and spinal degeneration.[ncbi.nlm.nih.gov] In later stages, spasticity, extensor plantar responses, greater loss of position and vibratory sensation in the lower extremities, and ataxia emerge.[merckmanuals.com] A clinical diagnosis of dementia with delirium was made.[doi.org]

  • Chronic Alcoholism

    Wernicke-Korsakoff syndrome (ataxia, confusion, ophthalmoplegia), amnesic problems, peripheral neuropathy and dementia.[patient.info] The concept of "structural plasticity" has emerged as a potential mechanism in neurodegenerative and psychiatric diseases such as drug abuse, depression, and dementia.[ncbi.nlm.nih.gov] NUTRITIONAL – of course, can lead to Thiamine deficiency -- Wernicke/Korsakoff -- Dry and Wet Beriberi, Niacin deficiency -- Pellagra (diarrhea, dementia, dermatitis), Folate[errolozdalga.com]

  • Paraneoplastic Syndrome

    Cerebellar symptoms : ataxia, unsteady gait, dysdiadochokinesia, intention tremor Note that symptoms often emerge months before the discovery of a primary tumor ![amboss.com] We report a fatal case of severe chronic progressive axonal polyradiculoneuropathy in association with this antibody.[doi.org] […] may include difficulty in walking or swallowing, loss of muscle tone, loss of fine motor coordination, slurred speech, memory loss, vision problems, sleep disturbances, dementia[ninds.nih.gov]

  • Pernicious Anemia

    We describe a case of a young black woman with gradually progressive lower extremity paresthesias, weakness, and ataxia as the primary presenting symptoms of pernicious anemia[ncbi.nlm.nih.gov] […] presentation mimicking a dementia of depression.[ncbi.nlm.nih.gov] ), ataxia and positive Babinski reflexes.[doi.org]

  • Subacute Combined Degeneration of Spinal Cord

    Case Presentation: A 28‐year‐old nursing student with a history of bipolar disorder presented to Tucson Medical Center with symptoms of ataxia and bilateral lower‐extremity[shmabstracts.com] He presented acutely with tremors, diaphoresis, insomnia, ataxia (progressive over the last three months), lower extremity paresthesias, decreased somatosensory perception[em-consulte.com] Mental changes range from mild forgetfulness to severe dementia or psychosis. Severe dementia is uncommon, but in some cases, it is the first symptom of the disorder.[nlm.nih.gov]

  • Thiamine Deficiency

    Nerve conduction studies were consistent with axonal, length-dependent polyneuropathy.[ncbi.nlm.nih.gov] […] found primarily in alcoholics are Wernicke’s encephalopathy (WE) and Korsakoff psychosis, which often combine as Wernicke-Korsakoff syndrome (WKS), ultimately leading to dementia[sovhealth.com] Alzheimer’s disease Scientists are studying the possibility that thiamin deficiency could affect the dementia of Alzheimer’s disease.[web.archive.org]

  • Autosomal Recessive Spinocerebellar Ataxia Type 17

    […] the extremities, truncal ataxia, increased reflexes in the lower extremities, and intellectual disability.[malacards.org] Clinical features Ataxia, chorea, and axonal polyneuropathy Cutaneous photosensitivity and multiple cancers Mental and motor retardation Microcephaly Sensorineural deafness[emedicine.medscape.com] It is characterized by a variable clinical picture which can include dementia, psychiatric disorders, parkinsonism, dystonia, chorea, spasticity, and epilepsy.[orpha.net]

  • Heavy Metal Poisoning

    In addition, non-inflammatory degenerative disease of the sensorimotor nerves (sensorimotor polyneuropathy) may advance to progressive deterioration (atrophy).[rarediseases.org] Local villagers ate the fish and began to exhibit signs of neurologic damage, such as visual loss, extremity numbness, hearing loss, and ataxia.[slideshare.net] We describe a patient who died of suspected heavy metal poisoning after a nine-month history of rapidly worsening dementia.[ncbi.nlm.nih.gov]

  • Familial Progressive Polyneuropathy

    Abstract The purpose of this study was to evaluate the clinical and pathological features in patients with progressive-type familial amyloidotic polyneuropathy (FAP) using[ncbi.nlm.nih.gov] […] with marked disturbances of sensation and ataxia of movement and caused by an interstitial hypertrophic neuritis that ascends with consecutive medullary [cord] lesions.[karger.com] The most prominent dementia is Alzheimer’s disease, but it has equally dreadful companions such as Frontotemporal dementia (FTD) and Dementia with Lewy bodies (DLB).[theneurologylounge.com]

  • Orthostatic Hypotension

    MSA is a progressive, adult-onset disorder characterized by a combination of autonomic dysfunction, parkinsonism, and ataxia.[emedicine.medscape.com] She had alternating Horner's syndrome, mild hypoalgesia of the right face, exaggerated deep tendon reflexes of the upper extremities, decreased deep sensation and ataxia of[ncbi.nlm.nih.gov] Abstract Regional cerebral blood flow was measured in 35 patients with organic dementia (Alzheimer's disease, n 13, vascular dementia, n 17, frontotemporal dementia, n 5)[ncbi.nlm.nih.gov]

Similar symptoms