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18 Possible Causes for Dementia, Hyperintensities in the Globus Pallidus (T2-Weighted), Pyramidal Tract Signs

Did you mean: Dementia, Hyperintensities in the Globus Pallidus (T2-Weighted, Pyramidal Tract Signs

  • Hallervorden-Spatz Syndrome

    Table-1: Diagnostic features of Hallervorden spatz disease [11] Obligate Features Collaborate Features Exclusion Features Onset during first two decades Pyramidal tract signs[medresearch.in] This virtually pathognomonic radiographic abnormality, called the eye-of-the-tiger sign, comprises hyperintensities within a hypointense medial globus pallidus on T2-weighted[ncbi.nlm.nih.gov] Serial assessments of a 29-year-old woman showed progressive dementia.[ncbi.nlm.nih.gov]

  • Binswanger Disease

    The bilateral cerebral white matter and globus pallidus appeared hyperintense on T2-weighted imaging (Figures 5 and 6). 5) Figure 5. CO poisoning(FLAIR image) Figure 6.[plaza.umin.ac.jp] Clinically, Lacunar Dementia presents with gait difficulties, urinary incontinence, parkinsonian features, pseudobulbar palsy, emotional incontinence and dementia.[ncbi.nlm.nih.gov] […] impact and features of the full range of cortical dementias.[books.google.ro]

  • Neurodegeneration with Brain Iron Accumulation

    . • Begins in childhood • Profound dystonia, dysarthria, spasticity and pyramidal tract signs • Pigmentary retinopathy, leading to night blindness and visual field constriction[slideshare.net] Even before the globus pallidus hypointensity developed, patients with mutations could be distinguished by the presence of isolated globus pallidus hyperintensity on T2-weighted[ncbi.nlm.nih.gov] We describe a case of late onset neurodegeneration with brain iron accumulation (NBIA) presenting as frontotemporal dementia (FTD) with amyotrophic lateral sclerosis (ALS)[ncbi.nlm.nih.gov]

  • Alexander Disease

    We report a case of genetically confirmed adult-onset AD with palatal myoclonus, pyramidal tract signs, cerebellar signs, and marked atrophy of the medulla oblongata and spinal[ncbi.nlm.nih.gov] In addition, there are symmetrical hyperintensity signals in the posterior part of the globus pallidus on T2-weighted images in the two symptomatic patients, which are rarely[ncbi.nlm.nih.gov] […] congenital disorder of nervous system Alexander's disease Alexander's disease (disorder) ALEXANDER DISEASE Megalencephaly in infancy accompanied by progressive spasticity and dementia[wikidata.org]

  • Central Pontine Myelinolysis

    In (CPM), the initial signs include dysarthria and dysphagia (secondary to corticobulbar fiber involvement), and flaccid quadriparesis (from pyramidal tract involvement) which[omicsonline.org] […] of Globus Pallidus (broad arrow), suggestive of Extrapontine myelinolysis.[ipfs.io] The complications of PCI were reported brain necrosis, seizure or dementia.[ncbi.nlm.nih.gov]

  • Neuroferritinopathy

    tract signs, and psychiatric symptoms.[ncbi.nlm.nih.gov] pallidus, on T2-weighted images.[emedicine.medscape.com] Speaker presentation Open Access Molecular Cytogenetics 2014 7 (Suppl 1) :I36 Burn; licensee BioMed Central Ltd. 2014 Published: 21 January 2014 Keywords Iron Dementia Blood[molecularcytogenetics.biomedcentral.com]

  • Creutzfeldt Jakob Disease

    Other neurologic findings may include cerebellar signs, pyramidal tract signs, extrapyramidal signs, corticla visual defects, abnormal extraocular movements, lower motor neuron[library.med.utah.edu] Extrapontine myelinolysis manifests predominantly as areas of bilateral FLAIR /T2-weighted imaging hyperintensity in the globus pallidus, putamen, and thalamus, which are[doi.org] Abstract Creutzfeldt-Jakob disease (CJD) is a rare prion disease that leads to a rapidly progressive dementia (RPD) and associated neurological features.[ncbi.nlm.nih.gov]

  • Mitochondrial Membrane Protein-Associated Neurodegeneration

    tract signs with heavy iron accumulation at the globus pallidum and the substantia nigra [ 1 , 2 ].[omicsonline.org] Key Diagnostic Features: Once the parkinsonian symptoms appear, brain MRI shows hypointensity in the region of substantia nigra (SN) and globus pallidus (GP) on T2-weighted[ajnr.org] Young onset dementias present significant diagnostic challenges.[ncbi.nlm.nih.gov]

  • Wilson Disease

    In Wilson disease, an abnormal striatum depicted on MR images correlated with pseudoparkinsonian signs, an abnormal dentatothalamic tract correlated with cerebellar signs,[pubs.rsna.org] On T1W images, these lesions are normal to hypointense but hyperintense lesions especially in globus pallidus may also be seen [ 2 ].[omcr.oxfordjournals.org] […] of Wilson’s disease in the United Kingdom Spastic pseudosclerosis (cortico-pallido-spinal degeneration), by Charles Davison (New York), Brain 1932: 55; 247–264 and Severe dementia[doi.org]

  • Beta-Propeller Protein-Associated Neurodegeneration

    . • Ataxia follows, and dysarthria and progressive spastic quadriparesis with pyramidal tract signs develop.[slideshare.net] Key Diagnostic Features: Once the parkinsonian symptoms appear, brain MRI shows hypointensity in the region of substantia nigra (SN) and globus pallidus (GP) on T2-weighted[ajnr.org] […] characterized by seizures and developmental delay or intellectual disability until adolescence or early adulthood, followed by severe dystonia, parkinsonism, and progressive dementia[ncbi.nlm.nih.gov]

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