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12 Possible Causes for Dementia, Involuntary Tongue Protrusion, Prominent Psychiatric Symptoms

  • Huntington Disease-Like 1

    It may resemble HD with prominent personality change, psychiatric symptoms and cognitive decline, chorea, rigidity, and dysarthria.[movementdisorders.org] […] aggressiveness, manias, anxiety and/or depression in conjunction with rapidly progressive cognitive decline (presenting with dysarthria, apraxia, aphasia, and eventually leading to dementia[orpha.net] Gerstmann-Straussler disease (sequence analysis of PRNP gene) Insomnia, fatal familial (sequence analysis of PRNP gene) Hereditary chorea (WES based NGS panel for 14 genes) Frontotemporal dementia[cgcgenetics.com]

  • Huntington Disease-Like 2

    Patients have prominent psychiatric symptoms, including becoming irritable and impulsive and sometimes aggressive.[burlingtonfreepress.com] However, clinical characteristics such as dystonia with prominent orofacial involvement with tongue protrusion, involuntary tongue- and lip-biting, head thrusts, and rubber[movementdisorders.org] Abstract Huntington disease-like 2 (HDL2) is an autosomal dominant disorder characterized by adult-onset, progressive motor abnormalities, psychiatric disturbances, and dementia[ncbi.nlm.nih.gov]

  • Huntington Disease-Like 3

    It may resemble HD with prominent personality change, psychiatric symptoms and cognitive decline, chorea, rigidity, and dysarthria.[movementdisorders.org] Like Huntington's disease (HD), it is an adult onset, progressive, neurodegenerative autosomal dominant disorder clinically characterized by abnormal movements, dementia,[jhu.pure.elsevier.com] Advanced Dementia Dementia is an impairment in the capacity for higher intellectual functions such as learning, reasoning, planning, social perception and adaptation.[livestrong.com]

  • Autosomal Recessive Spinocerebellar Ataxia Type 17

    It may resemble HD with prominent personality change, psychiatric symptoms and cognitive decline, chorea, rigidity, and dysarthria.[movementdisorders.org] It is characterized by a variable clinical picture which can include dementia, psychiatric disorders, parkinsonism, dystonia, chorea, spasticity, and epilepsy.[orpha.net] Dementia HRQL Instruments Not Optimized Although a number of HRQL instruments for dementia are available, their use to date may not be optimized, researchers have concluded[practicalneurology.com]

  • McLeod Neuroacanthocytosis Syndrome

    Patients with atypical disease who had PANK2 mutations were more likely to have prominent speech-related and psychiatric symptoms than patients with classic disease or mutation-negative[scienceopen.com] These symptoms may be referred to as orofacial and lingual dyskinesia and include protrusion of the tongue, grimacing, and abnormal jaw movements.[rarediseases.org] . • A variety of other neurologic symptoms may accompany neuroacanthocytosis, including seizures, motor neuron disease, and dementia.[medlink.com]

  • Spinocerebellar Ataxia Type 6

    Hattori, Homozygous Machado–Joseph disease presenting as REM sleep behaviour disorder and prominent psychiatric symptoms, European Journal of Neurology, 9, 1, (97-100), (2002[doi.org] They consisted of jaw-opening dystonia with almost rhythmic tongue protrusion, consistent with the dystonic tremor of the tongue (see Video 2, part IIIb).[movementdisorders.org] During this period, eye movement becomes slower down and some patient also has dementia in the latter stage of life.[healthsaline.com]

  • Familial Dyskinesia and Facial Myokymia

    It may resemble HD with prominent personality change, psychiatric symptoms and cognitive decline, chorea, rigidity, and dysarthria.[movementdisorders.org] No pyramidal, dementia or extrapyramidal findings occur. Patients are non-ambulatory within 20 years after onset.[neuroweb.us] Dear Readers, We invite you to read the following article recommendations, prepared for you by our Scientific Panels: Dementia and cognitive disorders, Higher cortical functions[eanpages.org]

  • Kleine-Levin Syndrome

    The common core symptoms of these syndromes are hypersomnolence and sleep drunkenness, with periodic hypersomnolence and hyperphagia being the prominent symptoms of KLS.[ncbi.nlm.nih.gov] Cataplexy in children is slightly different and a variety of symptoms and movements including tongue protrusion and involuntary arm movements have been described.[evelinalondon.nhs.uk] The types of stroke reported were a multi-infarct dementia ( Drake, 1987 ), a thalamic ischaemic stroke ( McGilchrist et al., 1993 ) and traumatic haemorrhages of the right[doi.org]

  • Quetiapine

    The most common sleep dysfunction is insomnia, which is a primary symptom in 30% to 90% of psychiatric disorders.[doi.org] TD's also include repetitive stereotypical movements of the face, tongue and limb such as sucking and smacking of the lips, lateral jaw movements and protrusions of the tongue[google.com] Method Participants were all people with dementia living in care facilities in Newcastle.[bmj.com]

  • Idiopathic Childhood-Onset Basal Ganglia Calcification

    It may resemble HD with prominent personality change, psychiatric symptoms and cognitive decline, chorea, rigidity, and dysarthria.[movementdisorders.org] Also, the typical presentation of so-called childhood-onset Huntington’s disease, characterized by rigidity instead of chorea, cerebellar signs, and rapidly progressive dementia[checkorphan.org] Other sites such as the vasculature or parenchyma are more often found in the context of clinical manifestations such as parkinsonism, dementia, psychosis and mood disorders[demneuropsy.com.br]

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