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997 Possible Causes for Dementia with Lewy Bodies, Mutation in the Prion Protein Gene, Progressive Action Tremor

  • Fatal Familial Insomnia

    He consequently developed excessive sweating, bilateral action tremors, and restlessness.[karger.com] […] to be due to dementia with Lewy bodies.[ncbi.nlm.nih.gov] Genetic investigation confirmed diagnosis of fatal familial insomnia (D178N mutation of the prion protein gene and Val/Met polymorphism on position 129 of the mutated allele[ncbi.nlm.nih.gov]

  • Creutzfeldt Jakob Disease

    FDG PET with 3D-SSP disclosed that the hypometabolic pattern mimicked that of dementia with Lewy bodies.[ncbi.nlm.nih.gov] We report a Japanese patient with Creutzfeldt-Jakob disease (CJD) with a V203I homozygous mutation of the prion protein gene (PRNP).[ncbi.nlm.nih.gov] This comprehensively described case illustrates that dementia with Lewy bodies can occur in young patients with atypical clinical presentation.[ncbi.nlm.nih.gov]

    Missing: Progressive Action Tremor
  • Parkinson's Disease

    […] reduction in speed and amplitude of repetitive actions) and at least one of the following: (i) muscular rigidity, (ii) 4–6 Hz rest tremor and (iii) postural instability not[doi.org] […] disease dementia (PDD), together known as the Lewy body dementias.[ncbi.nlm.nih.gov] (hand, leg or jaw; low frequency [4–5 Hz], asymmetric, disappears with action) - Excellent response to levodopa (70%–100%) - Progressive disorder - Severe levodopa-induced[dx.doi.org]

    Missing: Mutation in the Prion Protein Gene
  • Alzheimer Disease

    Dementia with Lewy bodies (DLB) is the second most common cause of dementia.[ncbi.nlm.nih.gov] Fatal familial insomnia, a prion disease with a mutation at codon 178 of the prion protein gene.[ncbi.nlm.nih.gov] […] with Lewy bodies.[ncbi.nlm.nih.gov]

    Missing: Progressive Action Tremor
  • Posterior Cortical Atrophy

    Posterior cortical atrophy (PCA) and dementia with Lewy bodies (DLB) have both been associated with occipital lobe hypometabolism on 18 F-FDG PET, whereas relative sparing[ncbi.nlm.nih.gov] […] of the prion protein gene.[ncbi.nlm.nih.gov] Dementia with Lewy bodies (DLB) is associated with less temporal lobe atrophy than AD, though posterior cortical atrophy may be greater.[ncbi.nlm.nih.gov]

    Missing: Progressive Action Tremor
  • Vascular Dementia

    Dementia with Lewy bodies (DLB) is similar to and often co-occurs with Parkinson's Disease .[disabilitysecrets.com] A minority of prion diseases is caused by mutation in the prion protein gene, PRNP.[jnnp.bmj.com] People with vascular dementia often have another type of dementia as well, such as Alzheimer’s disease or dementia with Lewy bodies.[slam.nhs.uk]

    Missing: Progressive Action Tremor
  • Dementia with Lewy Bodies

    Read more about getting a dementia diagnosis . Tests for dementia with Lewy bodies There's no single test for dementia with Lewy bodies.[nhs.uk] Abstract The authors describe a patient who had a point mutation at codon 232 of the prion protein gene, resulting in the substitution of methionine for arginine (M232R).[ncbi.nlm.nih.gov] Dementia with Lewy bodies might be the second most common form of degenerative dementia in the elderly.[ncbi.nlm.nih.gov]

    Missing: Progressive Action Tremor
  • Multi-Infarct Dementia

    Cerebrovascular disease is the third most common cause of dementia in old age after Alzheimer's disease and Lewy Body Dementia (1), accounting for 20% of cases compared to[gpnotebook.co.uk] A minority of prion diseases is caused by mutation in the prion protein gene, PRNP.[doi.org] The Lewy Body Society The Lewy Body Society is a registered charity whose purpose is to fund research into Dementia with Lewy Bodies (DLB).[ucl.ac.uk]

    Missing: Progressive Action Tremor
  • Senile Chorea

    It is an action tremor occurring during activity and is of greater amplitude when reaching for a target.[academic.sun.ac.za] Prevention and AD References Introduction Vascular Cognitive ImpairmentVascular Dementia Lewy Body Disease Dementia with Lewy Bodies Progressive Supranuclear Palsy Corticobasal[books.google.com] A 192-nucleotide insertion in the region of the prion protein gene ( PRNP ) encoding an octapeptide repeat in the prion protein, was found in a single family with HD phenotype[clinicalgate.com]

  • Neurodegenerative Disorder

    tremor, myoclonus, hyper-reflexia, and focal limb dystonia.[aao.org] Emerging diagnoses (37.4%) were dementia with Lewy bodies (DLB) in 29 subjects, Parkinson disease (PD) in 22, multiple system atrophy (MSA) in two, and mild cognitive impairment[ncbi.nlm.nih.gov] Emerging disorders were Parkinson's disease in nine patients, dementia with Lewy bodies in six, multiple system atrophy with predominant cerebellar syndrome in one, and mild[ncbi.nlm.nih.gov]

    Missing: Mutation in the Prion Protein Gene

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