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89 Possible Causes for Depigmented Skin Patch

  • Vitiligo

    The typical presentation is well-demarcated depigmented skin patches.[] People with dark skin may notice a loss of color inside their mouths. Will the Depigmented Patches Spread?[] Abstract Vitiligo is an asymptomatic but cosmetically disfiguring disorder that results in the formation of depigmented patches on skin and/or mucosae.[]

  • Systemic Scleroderma

    History Systemic sclerosis can have many different presentations. It involves the skin and many internal organs. Therefore, the presenting symptoms may differ among patients. Cutaneous pruritus is common. Raynaud phenomenon, or whitening of the hands on exposure to cold, is a common finding. Pain in the affected[…][]

  • Systemic Lupus Erythematosus

    WHAT IS KNOWN AND OBJECTIVES: Different population pharmacokinetics (PPK) models of tacrolimus have been established in various populations. However, the tacrolimus PPK model in paediatric systemic lupus erythematosus (PSLE) is still undefined. This study aimed to establish the tacrolimus PPK model in Chinese PSLE.[…][]

  • Acute Hepatic Porphyria

    Summary Epidemiology In the majority of European countries, the prevalence of acute hepatic porphyrias is around 1/75,000. In 80% of cases the patients are female, with the majority aged between 20 to 45 years. Clinical description All acute hepatic porphyrias can be accompanied by neuro-visceral attacks that[…][]

  • Cutaneous T-Cell Lymphoma

    Primary cutaneous T-cell lymphomas: a review Konstantinos G Sidiropoulos 1, M Estela Martinez-Escala 2, Oriol Yelamos 2, Joan Guitart 2, Michael Sidiropoulos 1, 3, 4 1 Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada 2 Department of Dermatology, Northwestern University,[…][]

  • Variegate Porphyria

    Variegate porphyria is an autosomal dominant genetic disease of heme metabolism in which partial or total protoporphyrin oxidase deficiency leads to cutaneous and neurological symptoms in childhood. The diagnosis is made by measuring the levels of this enzyme in feces, blood, or urine, while genetic testing is used for[…][]

  • Porphyria Cutanea Tarda

    A 53-year-old woman with blistering on the hands was diagnosed with porphyria cutanea tarda (PCT). At that time, she was treated with interferon for liver metastasis of a pancreas tumor since 7 years. Although apparently rare, PCT has been described as possible cutaneous manifestation both of hepatic tumors[…][]

  • Tinea Versicolor

    In dark-skinned people the lesions may be depigmented. The fungus fluoresces under Wood's light and may be easily identified in scrapings viewed under a microscope.[] The lesions of progressive macular hypomelanosis are not scaly, and the patches of vitiligo are depigmented rather than hypopigmented, differentiating them from those of tinea[] […] corneum with minimal inflammatory reaction. tinea versicolor a fungal infection of the skin caused by Malassezia furfur and characterized by finely desquamating, pale tan patches[]

  • Pityriasis Alba

    The patches in pityriasis alba are not totally depigmented as they are in vitiligo.[] The two diseases can be distinguished visually, as the rash of vitiligo has a very distinct border with a sharp line between normal and lighter-colored skin.[]

  • Pallister-Killian Syndrome

    A prenatally detected case of a rare mosaic tetrasomy 12p/trisomy 12p is reported, presenting as the well-known accessory isochromosome 12p and a supernumerary single 12p marker in 17/24 and 6/24 clones of cultured amniotic fluid cells, respectively. The chromosomal nature of both marker chromosomes was[…][]

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