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108 Possible Causes for Depigmented Skin Patch, Progressive Peripapillary Chorioretinal Atrophy

  • Porphyria Cutanea Tarda

    Bilateral, geographic, peripapillary chorioretinal atrophy is evident and shows progression over a significant period despite improving the PCT.[]

  • Vitiligo

    The typical presentation is well-demarcated depigmented skin patches.[] People with dark skin may notice a loss of color inside their mouths. Will the Depigmented Patches Spread?[] Abstract Vitiligo is an asymptomatic but cosmetically disfiguring disorder that results in the formation of depigmented patches on skin and/or mucosae.[]

    Missing: Progressive Peripapillary Chorioretinal Atrophy
  • Systemic Scleroderma

    Systemic Scleroderma (SSc) is an autoimmune disease that affects connective tissue, resulting in hardening skin, reduced vascular perfusion, gingival fibrosis, enlarged periodontal ligament, xerostomia, and trigeminal neuralgia. Secondary effects, including reduced oral opening and reduced manual dexterity may[…][]

    Missing: Progressive Peripapillary Chorioretinal Atrophy
  • Systemic Lupus Erythematosus

    Gain of function (GOF) mutations in PIK3CD gene encoding PI3K p110δ were recently associated with a novel combined immune deficiency characterized by recurrent sinopulmonary infections, CD4 lymphopenia, reduced class-switched memory B cells, lymphadenopathy, cytomegalovirus and/or epstein-Barr virus (EBV) viremia,[…][]

    Missing: Progressive Peripapillary Chorioretinal Atrophy
  • Acute Hepatic Porphyria

    Gut. 1994 Aug;35(8):1112-5. Author information 1 University Department of Medicine and Therapeutics, Western Infirmary, Glasgow. Abstract Patients with acute hepatic porphyria are denied essential operations because of concern that general anaesthesia and surgery will precipitate a life threatening porphyric crisis.[…][]

    Missing: Progressive Peripapillary Chorioretinal Atrophy
  • Cutaneous T-Cell Lymphoma

    Cutaneous T-cell lymphomas (CTCL) are characterized by an infiltration of the skin with malignant T cells. Curative treatments for aggressive entities such as Sézary syndrome have not been identified yet. Arsenic trioxide (AsO3) is used for the treatment of acute promyelocytic leukemia in combination with retinoids.[…][]

    Missing: Progressive Peripapillary Chorioretinal Atrophy
  • Variegate Porphyria

    The acute hepatic porphyrias can cause life-threatening attacks of neurovisceral symptoms that mimic other acute medical conditions. Variegate porphyria caused by mutations in the protoporphyrinogen oxidase (PPOX) gene is a latent disorder characterized by exacerbations induced by fasting, alcohol consumption or[…][]

    Missing: Progressive Peripapillary Chorioretinal Atrophy
  • Tinea Versicolor

    In dark-skinned people the lesions may be depigmented. The fungus fluoresces under Wood's light and may be easily identified in scrapings viewed under a microscope.[] The lesions of progressive macular hypomelanosis are not scaly, and the patches of vitiligo are depigmented rather than hypopigmented, differentiating them from those of tinea[] […] corneum with minimal inflammatory reaction. tinea versicolor a fungal infection of the skin caused by Malassezia furfur and characterized by finely desquamating, pale tan patches[]

    Missing: Progressive Peripapillary Chorioretinal Atrophy
  • Pityriasis Alba

    The patches in pityriasis alba are not totally depigmented as they are in vitiligo.[] The two diseases can be distinguished visually, as the rash of vitiligo has a very distinct border with a sharp line between normal and lighter-colored skin.[]

    Missing: Progressive Peripapillary Chorioretinal Atrophy
  • Pallister-Killian Syndrome

    Pallister-Killian syndrome (PKS) is a rare disorder characterized by a specific combination of anomalies, mental retardation and mosaic presence of a supernumerary isochromosome 12p which is tissue-limited. We report an atypical case of PKS with a mild phenotype. Flourescence in situ hybridization (FISH) was used to[…][]

    Missing: Progressive Peripapillary Chorioretinal Atrophy

Further symptoms